Citation: Peng Zhan, Xinyong Liu. Construction of an Integrated Teaching Case Library for Pharmaceutical Education: A Case Study on the Development of Anti-SARS-Cov-2 Drugs[J]. University Chemistry, ;2023, 38(12): 10-17. doi: 10.3866/PKU.DXHX202308077 shu

Construction of an Integrated Teaching Case Library for Pharmaceutical Education: A Case Study on the Development of Anti-SARS-Cov-2 Drugs

Peng Zhan ^, ,
Xinyong Liu

School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China

Corresponding author: Peng Zhan, zhanpeng1982@sdu.edu.cn
Received Date: 21 August 2023

The integration of research and teaching in pharmaceutical education provides valuable teaching materials for cultivating innovative pharmaceutical talents. The development of drugs against COVID-19 represents a concentrated embodiment of new strategies and technologies in the field of pharmacy, reflecting the high-level intelligence of pharmaceutical researchers. This article takes the development of anti-SARS-CoV-2 drugs as an example to explore and summarize the methods of constructing an integrated teaching case library for pharmaceutical education.
- Case teaching,
- Antiviral drugs,
- SARS-CoV-2,
- Pharmacy major,
- Teaching method
1. [1]
2. [2]
3. [3]
4. [4]
5. [5]
6. [6]
7. [7]
8. [8]
9. [9]
10. [10]
11. [11]
12. [12]
13. [13]
14. [14]
15. [15]
16. [16]
17. [17]
18. [18]
19. [19]
20. [20]
21. [21]
22. [22]
23. [23]
  ]. https://www.nsfc.gov.cn/publish/portal0/tab442/info89421.htm
24. [24]
25. [25]
26. [26]
27. [27]
  von Delft, A.; Hall, M. D.; Kwong, A. D.; Purcell, L. A.; Saikatendu, K. S.; Schmitz, U.; Tallarico, J. A.; Lee, A. A. Nat. Rev. Drug Discov. 2023, 22 (7), 585.
28. [28]
  Gao, S.; Huang, T.; Song, L.; Xu, S.; Cheng, Y.; Cherukupalli, S.; Kang, D.; Zhao, T.; Sun, L.; Zhang, J.; et al. Acta Pharm. Sin. B 2022, 12 (2), 581.
29. [29]
  Huang, T.; Sun, L.; Kang, D.; Poongavanam, V.; Liu, X.; Zhan, P.; Menéndez-Arias, L. Adv. Exp. Med. Biol. 2021, 1322, 219.
30. [30]
  Melidis, L.; Hill, H. J.; Coltman, N. J.; Davies, S. P.; Winczura, K.; Chauhan, T.; Craig, J. S.; Garai, A.; Hooper, C. A. J.; Egan, R. T.; et al. Angew. Chem. Int. Ed. 2021, 60 (33), 18144.
31. [31]
  Melidis, L.; Styles, I. B.; Hannon, M. J. Chem. Sci. 2021, 12 (20), 7174.
32. [32]
  Gao, S.; Song, L.; Claff, T.; Woodson, M.; Sylvester, K.; Jing, L.; Weiße, R. H.; Cheng, Y.; Sträter, N.; Schäkel, L.; et al. J. Med. Chem. 2022, 65 (24), 16902.
33. [33]
  Gao, S.; Sylvester, K.; Song, L.; Claff, T.; Jing, L.; Woodson, M.; Weiße, R. H.; Cheng, Y.; Schäkel, L.; Petry, M.; et al. J. Med. Chem. 2022, 65 (19), 13343.
34. [34]
35. [35]
36. [36]
  Drayman, N.; DeMarco, J. K.; Jones, K. A.; Azizi, S. A.; Froggatt, H. M.; Tan, K.; Maltseva, N. I.; Chen, S.; Nicolaescu, V.; Dvorkin, S.; et al. Science 2021, 373 (6557), 931.
37. [37]
38. [38]
39. [39]
  Chamakuri, S.; Lu, S.; Ucisik, M. N.; Bohren, K. M.; Chen, Y. C.; Du, H. C.; Faver, J. C.; Jimmidi, R.; Li, F.; Li, J. Y.; et al. Proc. Natl. Acad. Sci. USA 2021, 118 (36), e2111172118.
40. [40]
  Chaudhary, N.; Weissman, D.; Whitehead, K. A. Nat. Rev. Drug Discov. 2021, 20 (11), 817.
41. [41]
42. [42]
43. [43]
  Xue, S.; Xu, W.; Wang, L.; Wang, X.; Duan, Q.; Calcul, L.; Wang, S.; Liu, W.; Sun, X.; Lu, L.; et al. ACS Cent. Sci. 2023, 9 (5), 1046.
44. [44]
  Yu, B.; Li, S.; Tabata, T.; Wang, N.; Cao, L.; Kumar, G. R.; Sun, W.; Liu, J.; Ott, M.; Wang, L. Chem 2022, 8 (10), 2766.
45. [45]
  Li, Q.; Chen, Q.; Klauser, P. C.; Li, M.; Zheng, F.; Wang, N.; Li, X.; Zhang, Q.; Fu, X.; Wang, Q.; et al. Cell 2020, 182 (1), 85.
46. [46]
47. [47]
48. [48]
49. [49]
50. [50]
51. [51]
52. [52]
53. [53]
54. [54]
55. [55]
56. [56]
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