Citation: Kexing Ma, Xiao Zhang, Xin-Ping Hui, Quan-Xiang Wu. Advancements in Oral Antihypertensive Medication Research[J]. University Chemistry, ;2023, 38(12): 106-113. doi: 10.3866/PKU.DXHX202306030 shu

Advancements in Oral Antihypertensive Medication Research

1.
College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China;
2.
School of Public Health, Lanzhou University, Lanzhou 730000, China

Corresponding author: Xin-Ping Hui, Quan-Xiang Wu,
Received Date: 13 June 2023

This article reviews research on antihypertensive medications including vasodilators, β-blockers, and angiotensin II receptor antagonists that have been approved by the FDA (Food and Drug Administration) since 2011. It covers the discovery of lead compounds, mechanisms of action, structural modifications, structure-activity relationships, and synthesis methods, aiming to serve as a reference for the development of antihypertensive drugs.
- Antihypertensive drugs,
- Lead compounds,
- Structural modification,
- Structure-activity relationship
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沈阳化工大学材料科学与工程学院沈阳 110142