Citation: Yiming Li, Benhua Wang, Baosheng Wei, Xiangzhi Song, Yiming Luo, Guipeng Yu. Design, Multi-Path Synthesis and Characterization of Stellate Polyschiff Base: A Chemistry Scientific Training Experiment[J]. University Chemistry, ;2023, 38(12): 61-66. doi: 10.3866/PKU.DXHX202304090 shu

Design, Multi-Path Synthesis and Characterization of Stellate Polyschiff Base: A Chemistry Scientific Training Experiment

College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China

Corresponding author: Guipeng Yu, gilbertyu@csu.edu.cn
Received Date: 26 April 2023

The Comprehensive Science Training Experiment is a crucial component in the cultivation of top-notch talents in the field of scientific innovation. This article introduces a comprehensive experiment on the synthesis and characterization of a star-shaped polyamine in the organic chemistry science training course. Through this experiment, students can gain an understanding of the cutting-edge research and advancements in polyamine chemistry, apply their theoretical knowledge to design synthetic routes for target products, deepen their understanding of the basic principles and experimental methods of diazotization, Schiff base reaction, and Suzuki coupling reaction, master the techniques of monitoring reactions using thin-layer chromatography and separating products through column chromatography, and learn to characterize and identify compound structures using modern analytical methods such as nuclear magnetic resonance and infrared spectroscopy. This experiment not only cultivates students’ rigorous scientific attitude and research innovation consciousness but also trains their practical research skills. Furthermore, through diversified experimental approaches, it fosters students’ teamwork abilities, stimulates their enthusiasm, initiative, and creativity, and enhances their problem-analysis-and-solving capabilities.
- Schiff base,
- Suzuki coupling reaction,
- Comprehensive innovation experiment
1. [1]
  Anson, C. W.; Ghosh, S.; Hammes-Schiffer, S.; Stahl, S. S. J. Am. Chem. Soc. 2016, 138 (12), 4186.
2. [2]
3. [3]
4. [4]
  Elemans, J. A.; Wezenberg, S. J.; Coenen, M. J.; Escudero-Adan, E. C.; Benet-Buchholz, J.; den Boer, D.; Speller, S.; Kleij, A. W.; De Feyter, S. Chem. Commun. 2010, 46 (15), 2548.
5. [5]
  Li, L. H.; Feng, X. L.; Cui, X. H.; Ma, Y. X.; Ding, S. Y.; Wang, W. J. Am. Chem. Soc. 2017, 139 (17), 6042.
6. [6]
  Selvaraj, M.; Assiri, M. A. Dalton Trans. 2019, 48 (10), 3291.
7. [7]
8. [8]
9. [9]
1. [1]
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2. [2]
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3. [3]
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4. [4]
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5. [5]
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6. [6]
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7. [7]
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8. [8]
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10. [10]
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11. [11]
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12. [12]
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16. [16]
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17. [17]
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18. [18]
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19. [19]
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20. [20]
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