Citation: Manle Jiang,  Dang Zhang,  Jian Zhang,  Ping Xu,  Lei Wang. Micro/nanorobots: An “Ingenious Shocking Military” towards Cancer Treatment[J]. University Chemistry, ;2023, 38(11): 142-147. doi: 10.3866/PKU.DXHX202304034 shu

Micro/nanorobots: An “Ingenious Shocking Military” towards Cancer Treatment

  • In recent decades, an escalating incidence of tumors has been observed, necessitating more precise and less side-effect-prone therapies. Micro/nanorobots have been successfully engineered to address this challenge. These minute intelligent machines are capable of navigating to, and even infiltrating, tumor cells or tissues under external control. This enables targeted drug delivery and precise tumor therapy. To elucidate this sophisticated technology to a general audience, this paper adopts a personification style. Utilizing an engaging "battle narrative between micro/nanorobots and tumor cells", we briefly outline the design, fabrication, propulsion mechanisms, and therapeutic principles for a wider readership.
    1. [1]

    2. [2]

    3. [3]

      Wang, J.; Dong, R.; Wu, H.; Cai, Y.; Ren, B. Micro Nano Lett. 2020, 12, 11.

    4. [4]

      Lin, Z.; Gao, C.; Wang, D.; He, Q. Angew. Chem. Int. Edit. 2021, 60 (16), 8750.

    5. [5]

      Garcia-Gradilla, V.; Sattayasamitsathit, S.; Soto, F.; Kuralay, F.; Yardimci, C.; Wiitala, D.; Galarnyk, M.; Wang, J. Small 2014, 10 (20), 4154.

    6. [6]

      Ke, L.; Wei, F.; Liao, X.; Rees, T.; Kuang, S.; Liu, Z.; Chen, Y.; Ji, L.; Chao, H. Nanoscale 2021, 13 (16), 7590.

    7. [7]

      Song, X.; Chen, Z.; Zhang, X.; Xiong, J.; Jiang, T.; Wang, Z.; Geng, X.; Cheang, U. K. Sci. Rep. 2021, 11, 7907.

    8. [8]

      Song, X.; Fu, W.; Cheang, U. K. Iscience 2022, 25 (7), 104507.

    9. [9]

      Llopic-Lorente, A.; Garcia, A.; Murillo, N.; Hortelao, A. C.; Patino, T.; Villalonga, R.; Sancenon, F.; Martinez, R.; Sanchez, S. ACS Nano 2019, 13 (10), 12171.

    10. [10]

      Gong, D.; Geli, N.; Zhang, D.; Cai, J. ACS Appl. Mater. Inter. 2022, 14 (5), 6320.

    11. [11]

      Ceylan, H.; Yasa, I. C.; Yasa, O.; Tabak, A. F.; Giltinan, J.; Sitti, M. ACS Nano 2019, 13 (3), 3353.

    12. [12]

    13. [13]

      Kagan, D.; Laocharoensuk, R.; Zimmerman, M.; Clawson, C.; Balasubramanian, S.; Kong, D.; Bishop, D.; Sattayasamitsathit, S.; Zhang, L. F.; Wang, J. Small 2010, 6 (23), 2741.

    14. [14]

      Wang, D.; Gao, C.; Wang, W.; Sun, M.; Guo, B.; Xie, H.; He, Q. ACS Nano 2018, 12 (10), 10212.

    15. [15]

      Yang, H.; Wang, L.; Huang, X. Coordin. Chem. Rev. 2023, 495, 215372.

    1. [1]

    2. [2]

    3. [3]

      Wang, J.; Dong, R.; Wu, H.; Cai, Y.; Ren, B. Micro Nano Lett. 2020, 12, 11.

    4. [4]

      Lin, Z.; Gao, C.; Wang, D.; He, Q. Angew. Chem. Int. Edit. 2021, 60 (16), 8750.

    5. [5]

      Garcia-Gradilla, V.; Sattayasamitsathit, S.; Soto, F.; Kuralay, F.; Yardimci, C.; Wiitala, D.; Galarnyk, M.; Wang, J. Small 2014, 10 (20), 4154.

    6. [6]

      Ke, L.; Wei, F.; Liao, X.; Rees, T.; Kuang, S.; Liu, Z.; Chen, Y.; Ji, L.; Chao, H. Nanoscale 2021, 13 (16), 7590.

    7. [7]

      Song, X.; Chen, Z.; Zhang, X.; Xiong, J.; Jiang, T.; Wang, Z.; Geng, X.; Cheang, U. K. Sci. Rep. 2021, 11, 7907.

    8. [8]

      Song, X.; Fu, W.; Cheang, U. K. Iscience 2022, 25 (7), 104507.

    9. [9]

      Llopic-Lorente, A.; Garcia, A.; Murillo, N.; Hortelao, A. C.; Patino, T.; Villalonga, R.; Sancenon, F.; Martinez, R.; Sanchez, S. ACS Nano 2019, 13 (10), 12171.

    10. [10]

      Gong, D.; Geli, N.; Zhang, D.; Cai, J. ACS Appl. Mater. Inter. 2022, 14 (5), 6320.

    11. [11]

      Ceylan, H.; Yasa, I. C.; Yasa, O.; Tabak, A. F.; Giltinan, J.; Sitti, M. ACS Nano 2019, 13 (3), 3353.

    12. [12]

    13. [13]

      Kagan, D.; Laocharoensuk, R.; Zimmerman, M.; Clawson, C.; Balasubramanian, S.; Kong, D.; Bishop, D.; Sattayasamitsathit, S.; Zhang, L. F.; Wang, J. Small 2010, 6 (23), 2741.

    14. [14]

      Wang, D.; Gao, C.; Wang, W.; Sun, M.; Guo, B.; Xie, H.; He, Q. ACS Nano 2018, 12 (10), 10212.

    15. [15]

      Yang, H.; Wang, L.; Huang, X. Coordin. Chem. Rev. 2023, 495, 215372.

  • 加载中
    1. [1]

      Gaofeng Zeng Shuyu Liu Manle Jiang Yu Wang Ping Xu Lei Wang . Micro/Nanorobots for Pollution Detection and Toxic Removal. University Chemistry, 2024, 39(9): 229-234. doi: 10.12461/PKU.DXHX202311055

    2. [2]

      Shuyu Liu Xiaomin Sun Bohan Song Gaofeng Zeng Bingbing Du Chongshen Guo Cong Wang Lei Wang . Design and Fabrication of Phospholipid-Vesicle-based Artificial Cells towards Biomedical Applications. University Chemistry, 2024, 39(11): 182-188. doi: 10.12461/PKU.DXHX202404113

    3. [3]

      Xin Lv Hongxing Zhang Kaibo Duan Wenhui Dai Zhihui Wen Wei Guo Junsheng Hao . Lighting the Way Against Cancer: Photodynamic Therapy. University Chemistry, 2024, 39(5): 70-79. doi: 10.3866/PKU.DXHX202309090

    4. [4]

      Tingting XUWenjing ZHANGYongbo SONG . Research advances of atomic precision coinage metal nanoclusters in tumor therapy. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2275-2285. doi: 10.11862/CJIC.20240229

    5. [5]

      Di WURuimeng SHIZhaoyang WANGYuehua SHIFan YANGLeyong ZENG . Construction of pH/photothermal dual-responsive delivery nanosystem for combination therapy of drug-resistant bladder cancer cell. Chinese Journal of Inorganic Chemistry, 2024, 40(9): 1679-1688. doi: 10.11862/CJIC.20240135

    6. [6]

      Jiahui CHENTingting ZHENGXiuyun ZHANGWei LÜ . Research progress of near-infrared absorption inorganic nanomaterials in photothermal and photodynamic therapy of tumors. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2396-2414. doi: 10.11862/CJIC.20240106

    7. [7]

      Zhuoya WANGLe HEZhiquan LINYingxi WANGLing LI . Multifunctional nanozyme Prussian blue modified copper peroxide: Synthesis and photothermal enhanced catalytic therapy of self-provided hydrogen peroxide. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2445-2454. doi: 10.11862/CJIC.20240194

    8. [8]

      Peng GENGGuangcan XIANGWen ZHANGHaichuang LANShuzhang XIAO . Hollow copper sulfide loaded protoporphyrin for photothermal-sonodynamic therapy of cancer cells. Chinese Journal of Inorganic Chemistry, 2024, 40(10): 1903-1910. doi: 10.11862/CJIC.20240155

    9. [9]

      Wenjing ZHANGXiaoqing WANGZhipeng LIU . Recent developments of inorganic metal complex-based photothermal materials and their applications in photothermal therapy. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2356-2372. doi: 10.11862/CJIC.20240254

    10. [10]

      Zijian Jiang Yuang Liu Yijian Zong Yong Fan Wanchun Zhu Yupeng Guo . Preparation of Nano Zinc Oxide by Microemulsion Method and Study on Its Photocatalytic Activity. University Chemistry, 2024, 39(5): 266-273. doi: 10.3866/PKU.DXHX202311101

    11. [11]

      Qi Li Pingan Li Zetong Liu Jiahui Zhang Hao Zhang Weilai Yu Xianluo Hu . Fabricating Micro/Nanostructured Separators and Electrode Materials by Coaxial Electrospinning for Lithium-Ion Batteries: From Fundamentals to Applications. Acta Physico-Chimica Sinica, 2024, 40(10): 2311030-. doi: 10.3866/PKU.WHXB202311030

    12. [12]

      Yu Wang Shoulei Zhang Tianming Lv Yan Su Xianyu Liu Fuping Tian Changgong Meng . Introduce a Comprehensive Inorganic Synthesis Experiment: Synthesis of Nano Zinc Oxide via Microemulsion Using Waste Soybean Oil. University Chemistry, 2024, 39(7): 316-321. doi: 10.3866/PKU.DXHX202311035

    13. [13]

      Min Gu Huiwen Xiong Liling Liu Jilie Kong Xueen Fang . Rapid Quantitative Detection of Procalcitonin by Microfluidics: An Instrumental Analytical Chemistry Experiment. University Chemistry, 2024, 39(4): 87-93. doi: 10.3866/PKU.DXHX202310120

    14. [14]

      Xiutao Xu Chunfeng Shao Jinfeng Zhang Zhongliao Wang Kai Dai . Rational Design of S-Scheme CeO2/Bi2MoO6 Microsphere Heterojunction for Efficient Photocatalytic CO2 Reduction. Acta Physico-Chimica Sinica, 2024, 40(10): 2309031-. doi: 10.3866/PKU.WHXB202309031

    15. [15]

      Zhicheng JUWenxuan FUBaoyan WANGAo LUOJiangmin JIANGYueli SHIYongli CUI . MOF-derived nickel-cobalt bimetallic sulfide microspheres coated by carbon: Preparation and long cycling performance for sodium storage. Chinese Journal of Inorganic Chemistry, 2025, 41(4): 661-674. doi: 10.11862/CJIC.20240363

    16. [16]

      Siyi ZHONGXiaowen LINJiaxin LIURuyi WANGTao LIANGZhengfeng DENGAo ZHONGCuiping HAN . Targeting imaging and detection of ovarian cancer cells based on fluorescent magnetic carbon dots. Chinese Journal of Inorganic Chemistry, 2024, 40(8): 1483-1490. doi: 10.11862/CJIC.20240093

    17. [17]

      Changjun You Chunchun Wang Mingjie Cai Yanping Liu Baikang Zhu Shijie Li . 引入内建电场强化BiOBr/C3N5 S型异质结中光载流子分离以实现高效催化降解微污染物. Acta Physico-Chimica Sinica, 2024, 40(11): 2407014-. doi: 10.3866/PKU.WHXB202407014

    18. [18]

      Jiao CHENYi LIYi XIEDandan DIAOQiang XIAO . Vapor-phase transport of MFI nanosheets for the fabrication of ultrathin b-axis oriented zeolite membranes. Chinese Journal of Inorganic Chemistry, 2024, 40(3): 507-514. doi: 10.11862/CJIC.20230403

    19. [19]

      Hong LIXiaoying DINGCihang LIUJinghan ZHANGYanying RAO . Detection of iron and copper ions based on gold nanorod etching colorimetry. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 953-962. doi: 10.11862/CJIC.20230370

    20. [20]

      Guimin ZHANGWenjuan MAWenqiang DINGZhengyi FU . Synthesis and catalytic properties of hollow AgPd bimetallic nanospheres. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 963-971. doi: 10.11862/CJIC.20230293

Metrics
  • PDF Downloads(4)
  • Abstract views(569)
  • HTML views(123)

通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索
Address:Zhongguancun North First Street 2,100190 Beijing, PR China Tel: +86-010-82449177-888
Powered By info@rhhz.net

/

DownLoad:  Full-Size Img  PowerPoint
Return