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Citation: Lei Huang, Lei Zheng, Lei Bao, Li Nie, Xucheng Fu. Synthesis of Quinoline Compounds and the Effect of Their Structures on Anion Colorimetric Sensing: A Research-Based Comprehensive Experiment[J]. University Chemistry, ;2023, 38(11): 163-170. doi: 10.3866/PKU.DXHX202302069 shu

Synthesis of Quinoline Compounds and the Effect of Their Structures on Anion Colorimetric Sensing: A Research-Based Comprehensive Experiment

Basic Experimental Center, West Anhui University, Lu'an 237012, Anhui Province, China

Corresponding author: Lei Huang, hlei324@163.com
Received Date: 27 February 2023

This paper introduces a research-based comprehensive experiment involving the synthesis of quinoline derivatives and investigations on the effect of their structures on the colorimetric sensing performance of anions. During this experiment, students will learn and master the synthesis and characterization methods used for quinoline heterocyclic compounds and their derivatives. Based on the principle of organic small molecule sensing and recognition, students will learn to use ultraviolet-visible absorption spectroscopy instrumentation and study the anion sensing and recognition performance of quinoline compounds (P1, P2, and P3) as probes. Using the spectral data processed by Origin and visualized colorimetric images, students can better intuitively understand the anion sensing and recognition performance of different probes, along with the significance of the probe molecular structure in regulating sensing performance.
- Comprehensive experiment,
- Qunioline compounds,
- Colorimetric sensing,
- Probe
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