Citation:
Shengzhi Xue, Jinlong Bi, Xin-Ping Hui, Quan-Xiang Wu. Research Progress of Commercial Small-Molecule Antiviral Drugs[J]. University Chemistry,
;2023, 38(12): 91-105.
doi:
10.3866/PKU.DXHX202212054
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The COVID-19, AIDS, influenza, and other infectious viral diseases have a significant impact on human health, and new antiviral drugs are continuously emerging to combat these diseases. Herein, aiming at anti-SARS-CoV-2, anti-HIV, and anti-influenza virus, the latest research progress of small-molecule drugs is reported in this paper. The discovery process, mechanism of action, synthesis process, and structure-activity relationship research of each drug are systematically expounded to promote antiviral drug research and development.
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Keywords:
- Antiviral drugs,
- CIOVID-19,
- AIDS,
- Influenza,
- Small molecule drugs
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