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Citation: Pingping Tang. Amazing Chiral Spiro Catalyst: Analysis of Problem 8 of the 54th International Chemistry Olympiad[J]. University Chemistry, ;2022, 37(12): 220905. doi: 10.3866/PKU.DXHX202209051 shu

Amazing Chiral Spiro Catalyst: Analysis of Problem 8 of the 54th International Chemistry Olympiad

Pingping Tang ^,

College of Chemistry, Nankai University, Tianjin 300071, China

Corresponding author: Pingping Tang, ptang@nankai.edu.cn
Received Date: 20 September 2022

Chiral compounds are very important in people’s life and health. Taking the chiral spiro catalyst developed by the team of academician Zhou Qilin of Nankai University as the main content of the 54th International Chemistry Olympiad, problem 8 investigated the synthesis route of chiral spiro ligand SpiroPAP, the preparation of chiral spiro catalyst Ir-SpiroPAP, and the application of chiral spiro catalyst in the synthesis of natural products.
- Chirality,
- Spiro catalysts,
- Organic synthesis,
- Iridium,
- Complex
1. [1]
  Eleil, E. L.; Wilen, S. H.; Mander, L. N. Stereochemistry of Organic Compounds; Wiley-Interscience: New York, USA, 1994.
2. [2]
  Aitken, R. A.; Kilényi, S. N. Asymmetric Synthesis; Chapman & Hall: London, UK, 1992.
3. [3]
  Noyori, R. Asymmetric Catalysis in Organic Synthesis; Wiley-Interscience: New York, USA, 1994.
4. [4]
  Nógrádi, M. Stereoselective Synthesis; VCH: Weinheim, Germany, 1995.
5. [5]
  Yoon, T. P.; Jacobsen, E. N. Science 2003, 299, 1691.
6. [6]
  Xie, J. H.; Zhou, Q. L. Acc. Chem. Res. 2008, 41, 581.
7. [7]
  Zhu, S. F.; Zhou, Q. L. Acc. Chem. Res. 2017, 50, 988.
8. [8]
  Xie, J. H.; Liu, X. Y.; Xie, J. B.; Wang, L, X.; Zhou, Q. L. Angew. Chem. Int. Ed. 2011, 50, 7329.
9. [9]
  ]. www.icho2022.cn
10. [10]
  Birman, V. B.; Rheingold, A. L.; Lam, K. C. Tetrahedron-Asymmetry 1999, 10, 125.
11. [11]
  Liu, Y. T.; Li, L. P.; Xie, J. H.; Zhou, Q. L. Angew. Chem. Int. Ed. 2017, 56, 12708.
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