Citation: Yi Wu, Rui Liu, Yi Lv. 吉妥单抗复兴史[J]. University Chemistry, ;2022, 37(9): 220606. doi: 10.3866/PKU.DXHX202206066 shu

吉妥单抗复兴史

Yi Wu ¹ ,
Rui Liu ^1,, ,
Yi Lv ²

1.
College of Chemistry, Sichuan University, Chengdu 610064, China;
2.
Analytical & Testing Center, Sichuan University, Chengdu 610064, China

Corresponding author: Rui Liu, liur@scu.edu.cn
Received Date: 20 June 2022

采用访谈的形式，以首个上市的抗体偶联药物“吉妥单抗”的传奇历程为明线，靶向药物在化学分子设计和分析检测上的进步为暗线，讲述了抗体偶联药物的发展史。较为全面地介绍了抗体偶联药物的化学结构、设计思路、分析方法与发展前景。
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