Citation: Yuxin Wen, Hui Chao. 生物内源性SO₂的荧光检测[J]. University Chemistry, ;2022, 37(3): 211100. doi: 10.3866/PKU.DXHX202111006 shu

生物内源性SO₂的荧光检测

Yuxin Wen ,
Hui Chao ^,

MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou 510006, China

Corresponding author: Hui Chao, ceschh@mail.sysu.edu.cn
Received Date: 1 November 2021

SO₂作为空气污染物而被人们熟知，但鲜有人知道在生物体内SO₂也能内源性生成并作为信号分子参与生物体代谢循环，与我们的健康息息相关。SO₂在低浓度的时候具有舒张血管、抑制炎症、抗氧化和调节脂质代谢的作用，而在高浓度的时候则会引起某些呼吸道疾病、神经系统紊乱甚至是癌症。由此可见，更深入和全面地了解SO₂对维持生物体内系统的稳态和保持生物健康至关重要。本文以生物体内的SO₂为线索，从内源性生成，生理作用和荧光检测三大方面阐述了以SO₂为代表的新型信号分子在生物体内的流通和检测手段的演变。
- Endogenous sulfur dioxide,
- Physiological effect,
- Fluorescence detection
1. [1]
  Lim, M. H.; Lippard, S. J. Acc. Chem. Res. 2007, 40 (1), 41.
2. [2]
  (b) Mitsuhashi, H.; Yamashita, S.; Ikeuchi, H.; Kuroiwa, T.; Kanelo, Y.; Hiromura, K.; Ueki, K.; Nojima, Y. Shock 2005, 24, 229.
3. [3]
  Chen, E. Q.; Tang, Y. H.; Wang, L.; Ren, J. B.; Lin, W. Y. Chin. J. Org. Chem. 2021, 41 (3), 1200.
4. [4]
  (c) Stipanuk Annu, M. H. Rev. Nutr. 1986, 6, 179.
5. [5]
  Wang, X.; Sun, J.; Zhang, W. H.; Ma, X. X.; Lv, J. Z.; Tang, B. Chem. Sci. 2013, 4 (6), 2551.
6. [6]
  (d) Cipollone, R.; Ascenzi, P.; Tomao, P.; Imperi, F.; Visca, P. J. Mol. Microbiol. Biotechnol. 2008, 15, 199.
7. [7]
  (b) Otsuki, J.; Harada, K.; Araki, K. Chem. Lett. 1999, 28 (3), 269.
8. [8]
  Sulfur Dioxide:Endogenous Generation, Biological Effects, Detection, and Therapeutic Potential.[2021-10-29]. https://www.liebertpub.com/doi/10.1089/ars.2021.0213
9. [9]
10. [10]
  (c) Otsuki, J.; Tsujino, M.; Lizaki, T.; Araki, K.; Seno, M.; Takatera, K.; Watanabe, T. J. Am. Chem. Soc. 1997, 119 (33), 7895.
11. [11]
  (d) Sun, S.; Lees, A. J. J. Am. Chem. Soc. 2000, 122 (37), 8956.
12. [12]
  Jiao, X. Y.; Li, Y.; Niu, J. Y.; Xie, X. L.; Wang, X.; Tang, B. Anal. Chem. 2018, 90 (1), 533.
13. [13]
  Ji, A. J.; Savon, S. R.; Jacobsen, D. W. Clin. Chem. 1995, 41 (6), 897.
14. [14]
  (e) Pourrieux, G.; Fagalde, F.; Romero, I.; Fontrodona, X.; Parella, T.; Katz, N. E. Inorg. Chem. 2010, 49 (9), 4084.
15. [15]
  (b) Ghosal, K.; Sarkar, K. ACS Biomater. Sci. Eng. 2018, 4, 2653.
16. [16]
  Yang, B.; Xu, J.; Zhu, H. L. Free Radic. Bio. Med. 2019, 145, 42.
17. [17]
  Zhang, H. Y.; Xue, S. H.; Feng, G. Q. Sens. Actuators B Chem. 2016, 231, 752.
18. [18]
  (c) Zhu, S.; Song, Y.; Wang, J.; Wan, H.; Zhang, Y.; Ning, Y.; Yang, B. Nano Today 2017, 13, 10.
19. [19]
  (d) Zhu, S.; Shao, J.; Song, Y.; Zhao, X.; Du, J.; Wang, L.; Wang, H.; Zhang, K.; Zhang, J.; Yang, B. Nanoscale 2015, 7 (17), 7927.
20. [20]
  Huo, F. J.; Wu, Q.; Yin, C. Y.; Zhang, W. J.; Zhang, Y. B. Spectrochim. Acta, Part A 2019, 214, 429.
21. [21]
  Zhang, W. J.; Huo, F. J.; Zhang, Y. B.; Yin, C. X. J. Mater. Chem. B 2019, 7, 1945.
22. [22]
  (b) Mudd, S. H.; Irreverre, F.; Laster, L. Science 1967, 156 (3782), 1599.
23. [23]
  Stipanuk, M. H.; Dominy J. E., Jr.; Lee, J.; Coloso, R. M. J. Nutr. 2006, 136, 1652S.
24. [24]
  Sun, Y. Q.; Jing, L.; Zhang, J. Y.; Yang, T.; Guo, W. Chem. Commum. 2013, 49 (26), 2637.
25. [25]
  Li, G. Y.; Chen, Y.; Wang, J. Q.; Lin, Q.; Zhao, J.; Ji, L. N.; Chao, H. Chem. Sci. 2013, 4 (12), 4426.
26. [26]
  (a) Stipanuk, M. H.; Rosa, J. D.; Hirschberger, L. L. J. Nutr. 1990, 120, 450.
27. [27]
  Li, G. Y.; Chen, Y.; Wang, J. Q.; Wu, J. H.; Gasser, G.; Ji, L. N.; Chao, H. Biomaterials 2015, 63, 128.
28. [28]
  (a) Otsuki, J.; Sato, K.; Tsujino, M.; Okuda, N.; Araki, K.; Seno, M. Chem. Lett. 1996, 25 (10), 847.
29. [29]
  Li, G. Y.; Chen, Y.; Wang, J. Q.; Lin, Q.; Zhao, J.; Ji, L. N.; Chao, H. Chem. Sci. 2013, 4 (12), 4426.
30. [30]
  Chen, W. Q.; Fang, Q.; Yang, D. L.; Zhang, H. Y.; Song, X. Z.; Foley, J. Anal. Chem. 2015, 87 (1), 609.
31. [31]
  Li, G. Y.; Chen, Y.; Wang, J. Q.; Wu, J. H.; Gasser, G.; Ji, L. N.; Chao, H. Biomaterials 2015, 63, 128.
32. [32]
  (a) Chandra, A.; Deshpande, S.; Shinde, D. B.; Pillai, V. K.; Singh, N. ACS Macro Lett. 2014, 3 (10), 1064.
33. [33]
  Yuan, L.; Lin, W.; Zheng, K.; Zhu, S. Acc. Chem. Res. 2013, 46 (7), 1462.
34. [34]
  Li, G. H.; Ma, Y. Y.; Pei, M. S.; Lin, W. Y. Anal. Chem. 2019, 91 (22), 14586.
35. [35]
  Zhang, W. J.; Huo, F. J.; Cheng, F. Q.; Yin, C. X. J. Am. Chem. Soc. 2020, 142 (13), 6324.
36. [36]
  Feng, G. F.; Luo, X. Y.; Lu, X.; Xie, S. Y.; Deng, L.; Kang, W. Y.; He, F.; Zhang, J. H.; Lei, C. Y.; Lin, B.; et al. Angew. Chem. 2019, 58 (20), 6590.
37. [37]
  (a) Kisker, C.; Schindelin, H.; Pacheco, A.; Wehbi, W. A.; Garrett, R. M. Cell 1997, 91 (7), 973.
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生物内源性SO2的荧光检测

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生物内源性SO₂的荧光检测