Citation: Ying Wen, Ning Jing, Caixia Yin. 酯酶荧光探针的研究现状与进展[J]. University Chemistry, ;2022, 37(3): 211003. doi: 10.3866/PKU.DXHX202110036 shu

酯酶荧光探针的研究现状与进展

Institute of Molecular Science, Shanxi University, Taiyuan 030006, China

Corresponding author: Caixia Yin, yincx@sxu.edu.cn
Received Date: 12 October 2021

酯酶是一类丝氨酸蛋白酶，在生物体内被用于催化许多含有酯、酰胺、硫酯或乙酰基的化合物的水解。在生物体内，酯酶不仅起着重要的生理事件调节功能，参与各类药物的水解或激活，而且还参与许多病理事件（如肝癌），这可能与它独特的解毒功能有着密切的关系。因此，开发新的、有效的酯酶检测平台对生物和医学研究具有重要意义。与传统手段相比，荧光探针具有灵敏度高、选择性好、响应迅速、成本低、操作方便等诸多优势。因此用荧光探针检测酯酶是个很好的选择。本文主要综述了检测酯酶荧光探针的研究现状及最新进展。
- Esterases,
- Fluorescence probe,
- Detection
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