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Citation: Bing Li, Xinxin Zhao, Wujiong Xia, Yunchen Du, Xijiang Han. 紫外光诱导1-甲基-2-苯基吲哚啉的合成与表征——国家自然科学基金项目转化的综合型微量有机化学实验[J]. University Chemistry, ;2022, 37(7): 210903. doi: 10.3866/PKU.DXHX202109039 shu

紫外光诱导1-甲基-2-苯基吲哚啉的合成与表征——国家自然科学基金项目转化的综合型微量有机化学实验

School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China

Received Date: 10 September 2021

光化学反应是近年来备受青睐的有机合成策略之一，以吲哚啉杂环为骨架的化合物具有多样生物活性，如抗真菌、灭杀害虫、治疗代谢疾病药物等。基于课题组在自然科学基金项目研究中开创的一种绿色光化学吲哚啉合成方法，将部分研究成果设计转化为一个环保型的微量有机化学实验，即在光照下引发苯乙烯和N-甲基邻碘苯胺发生[3 + 2]自由基环合反应合成1-甲基-2-苯基吲哚啉。将前沿科研成果引入本科生实验教学，既丰富了实验教学内容，又提高了实验教学层次，同时也有助于学生树立“绿色化学”理念，拓宽知识体系。
- UV-light chemistry,
- Indoline,
- Green chemistry,
- Laboratory teaching
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