Citation: Sijia Xiang, Yangzhong Liu. 微量元素铜与人体生理功能和疾病[J]. University Chemistry, ;2022, 37(3): 210712. doi: 10.3866/PKU.DXHX202107128 shu

微量元素铜与人体生理功能和疾病

Sijia Xiang ,
Yangzhong Liu ^,

School of Chemistry and Materials Science, University of Science and Technology of China, Hefei 230026, China

Corresponding author: Yangzhong Liu, liuyz@ustc.edu.cn
Received Date: 31 July 2021

铜是人体中重要的微量金属元素之一，在多种生命活动中起着不可或缺的作用，包括电子传递、线粒体功能以及多种酶的活性。铜的缺乏或过量都会对人体产生严重、甚至是致命的危害，所以铜的摄取、胞内组装和代谢都需要严格的调控。铜的内稳态平衡的破坏可以导致贫血、威尔逊疾病和门克斯疾病，并严重影响大脑的功能。近年来的研究发现，肿瘤的生长、免疫系统的功能也与铜有着密不可分的联系。本文介绍铜在人体中的生物学功能、铜蛋白的作用以及铜的运输机制及储存机制，并对铜与相关疾病的关系进行讨论。
- Copper,
- Essential trace element,
- Copper protein,
- Copper transport,
- Disease
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