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Citation: Wenbin Chen, Yueyang Chen, Bo Chen. 环己醇制备环己酮的实验改进[J]. University Chemistry, ;2021, 36(8): 201104. doi: 10.3866/PKU.DXHX202011045 shu

环己醇制备环己酮的实验改进

College of Chemistry, Nankai University, Tianjin 300071, China

Corresponding author: Wenbin Chen, wbchen@nankai.edu.cn
Received Date: 20 November 2020

对本科生有机化学实验“环己醇氧化制备环己酮”进行了改进，尝试了两种绿色氧化剂：单过硫酸氢钾（Oxone）和三氯异氰尿酸（TCCA）。以Oxone氧化环己醇制备环己酮的反应时，发现了一个副产物，通过气质联用方法确定了副产物的结构，并研究了不同条件下的主产物和副产物含量。而利用TCCA氧化环己醇制备环己酮时，可得到高纯度的目标产物，其含量达93%左右，副产物含量较低，可以用来替代原有的重铬酸钠氧化环己醇制备环己酮的本科实验教学。通过引入绿色化学的概念，加深学生对绿色化学的认识，感受绿色化学在有机合成中的重要性，并激发了他们对科学研究的兴趣。更为重要的是引导学生在化学实验中注意新的发现，并对新的发现寻根索源，了解其原因和过程，并找到解决的方法。
- Green chemistry,
- Cyclohexanol,
- Cyclohexanone,
- Oxone,
- TCCA
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