Citation: Jie Han, Wenbin Chen, Yuxin Li, Rujiang Ma, Zhengjie He. (-)-薄荷酮的制备及比旋光度测定——介绍一个研究型有机化学实验[J]. University Chemistry, ;2021, 36(8): 201006. doi: 10.3866/PKU.DXHX202010060 shu

(-)-薄荷酮的制备及比旋光度测定——介绍一个研究型有机化学实验

National Demonstration Center for Experimental Chemistry Education, College of Chemistry, Nankai University, Tianjin 300071, China

Received Date: 26 October 2020

以（-）-薄荷醇为原料，采用重铬酸钠或次氯酸钠为氧化剂制备（-）-薄荷酮，比较了不同氧化方法的特点。测定了产物的比旋光度，并通过气相色谱对实验结果进行了分析，讨论了（-）-薄荷酮与（+）-薄荷酮之间的差向异构化作用对比旋光度的影响。本实验涉及加热回流、蒸馏、萃取、过滤等基本操作以及气相色谱表征与比旋光度的测定与分析，有利于培养学生基本操作技能，培养综合分析能力。
- Organic chemistry experiment,
- (-)-Menthone,
- Specific rotation,
- Epimerization
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