Citation: Lei Zhou. Metrics to Green Chemistry[J]. University Chemistry, ;2021, 36(6): 200703. doi: 10.3866/PKU.DXHX202007030 shu

Metrics to Green Chemistry

Lei Zhou ^,

School of Chemistry, Sun Yat-Sen University, Guangzhou 510275, China

Corresponding author: Lei Zhou, zhoul39@mail.sysu.edu.cn
Received Date: 9 July 2020

This paper introduces the main metrics that have been commonly used to test and compare the "greenness" of processes and products, including atom economy, the carbon efficiency, the reaction mass efficiency, the environmental fact, the environmental quotient, the process mass intensity, the life cycle assessment and the green aspiration level. The definition, difference and connection of these metrics are described in detail. Application examples are also presented to illustrate key concepts and their calculation. The green metrics cover aspects of starting materials, processing, products, wastes, and amongst others. The advent of these metrics not only promotes the advances of green chemistry, but also drives business, government and communities towards the standard of more sustainable practices.
- Green chemistry,
- Metrics,
- Green aspiration level
1. [1]
  Zimmerman, J. B.; Anastas, P. T.; Erythropel, H. C.; Leitner, W. Science 2020, 367, 397.
2. [2]
  Anastas, P. T.; Warner, J. C. Green Chemistry:Theory and Practice; Oxford University Press:New York, USA, 1998.
3. [3]
4. [4]
  Constable, D. J. C.; Curzons, A. D.; Cunningham, V. L. Green Chem. 2002, 4, 521.
5. [5]
  Curzons, A. D.; Constable, D. J. C.; Mortimer, D. N.; Cunningham, V. L. Green Chem. 2001, 3, 1.
6. [6]
  Jiménez-González, C.; Constable, D. J. C.; Ponder, C. S. Chem. Soc. Rev. 2012, 41, 1485.
7. [7]
  Trost, B. M. Science 1991, 254, 1471.
8. [8]
  Trost, B. M.; Livingston. R. C. J. Am. Chem. Soc. 1995, 117, 9586.
9. [9]
  Jiménez-González, C.; Ponder, C. S.; Broxterman, Q. B.; Manley, J. B. Org. Process Res. Dev. 2011, 15, 912.
10. [10]
  Sheldon, R. A. Chem. Ind. 1992, 903.
11. [11]
  Sheldon, R. A. Green Chem. 2017, 19, 18.
12. [12]
  Dunn, P. J.; Galvin, S.; Hettenbach. K. Green Chem. 2004, 6, 43.
13. [13]
  Jiménez-González, C.; Ollech, C.; Pyrz, W.; Hughes, D.; Broxterman, Q. B.; Bhathela, N. Org. Process Res. Dev. 2013, 17, 239.
14. [14]
  Henderson, R. K.; Constable, D. J. C.; Jiménez-González, C. Green Chemistry Metrics. In Green Chemistry in the Pharmaceutical Industry;Dunn, P.; Wells, A.; Williams, M. T. Eds.; Wiley-VCH Verlag GmbH & Co, Weinheim, Germany, 2010; pp. 21−48.
15. [15]
  Curzons, A. D.; Jiménez-González, C.; Duncan, A. L.; Constable, D. J. C.; Cunningham, V. L. Int. J. Life Cycle Assess. 2007, 12, 272.
16. [16]
  Roschangar, F.; Sheldon, R. A.; Senanayake, C. H. Green Chem. 2015, 17, 752.
17. [17]
  Roschangar, F.; Colberg, J.; Dunn, P. J.; Gallou, F.; Hayler, J. D.; Koenig, S. G.; Kopach, M. E.; Leahy, D. K.; Mergelsberg, I.; Tucker, J. L.; et al. Green Chem. 2017, 19, 281.
18. [18]
  Li, J.; Eastgate, M. D. Org. Biomol. Chem. 2015, 13, 7164.
19. [19]
  Green Chemistry Innovation Scorecard Calculator.[2020-07-07]. https://www.acs.org/content/acs/en/greenchemistry/research-innovation/tools-for-green-chemistry/green-chemistry-innovation-scorecard-calculator.html
20. [20]
  Roschangar, F.; Zhou, Y.; Constable, D. J. C.; Colberg, J.; Dickson, D. P.; Dunn, P. J.; Eastgate, M. D.; Gallou, F.; Hayler, J. D.; Koenig, S. G.;et al. Green Chem. 2018, 20, 2206.
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