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Citation: Lihui Jiang, Guohui Chen, Weihong Wang, Yingping Zou, Yiming Luo. Design of Separation Experiment of Three Components of Benzoic Acid, p-Methylaniline and Acetanilide[J]. University Chemistry, ;2020, 35(1): 98-104. doi: 10.3866/PKU.DXHX201904048 shu

Design of Separation Experiment of Three Components of Benzoic Acid, p-Methylaniline and Acetanilide

College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, P. R. China

Received Date: 26 April 2019

Separation and purification is the key step in organic synthesis, which is 90% of the total work. To train undergraduates' laboratory skill of separation and purification from the crude product or mixture and improve their understanding ability of using the theory of extraction, distillation, recrystallization, the "Separation of three organic component mixtures" is arranged by the organic chemistry teaching group at the College of Chemistry and Chemical Engineering, Central South University. Students include the five-year and eight-year medical clinic, pharmaceutical and applied chemistry. In this paper, the two teaching schemes of acid and alkali separation in this experiment are discussed in detail, and the laboratory teaching effects of the two schemes are compared.
- Three components,
- Separation and purification,
- Organic laboratory teaching,
- ¹H NMR characterization
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