Citation:
MA Xinyu, WANG Zhipeng A., TIAN Jie, JIANG Zhenxiong, GOU Yunzi, YAN Huijuan, XU Bing. Discussion on the Chemical Principles of Amino Acid Metabolism Based on Three Non-Polar Amino Acids[J]. University Chemistry,
;2019, 34(3): 23-31.
doi:
10.3866/PKU.DXHX201805046
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Considering the diversity and relative independence of amino acid metabolic pathways, the introduction and expansion of contents related to undergraduate education are important to foster a new generation of promising interdisciplinary researchers of the 21st century. This manuscript applies three non-polar natural amino acids, Val, Ile, and Leu, as examples to the exploring of a novel teaching example for lecturing the contents and methods of amino acid metabolism. The manuscript also attempts to generalize and summarize the reasons and logics behind the choices that nature makes for these metabolic pathways. Meanwhile, the biochemical processes involved reflects some unusual metabolic pathways and chemical reaction principles in life science. These pieces of knowledge are not only attractive and inspiring materials for undergraduate education, but also an effective way to illustrate current research frontiers. This manuscript is looking forward to helping students in their further studies and researches.
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Keywords:
- Valine,
- Isoleucine,
- Leucine,
- Umpolung,
- Metabolism,
- Thiamine pyrophosphate
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