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Citation: DU Chengtang, ZHANG Yubin, ZHAO Dongdong, ZHANG Jun, LI Kai. Ortho Lithiation and Lithium-Halogen Exchange of Aromatic Halide[J]. University Chemistry, ;2018, 33(6): 26-32. doi: 10.3866/PKU.DXHX201712027 shu

Ortho Lithiation and Lithium-Halogen Exchange of Aromatic Halide

Jiangsu Ascentage Pharma Development Co., Ltd., Taizhou 225300, Jiangsu Province, P. R. China

Received Date: 18 December 2017

In this paper, the mechanism, influence factor and application examples for ortho lithiation reaction and lithium-halide exchange reaction of aromatic compounds were introduced. The similarities and differences between these two reaction are discussed, so that readers can well master and apply this two important synthesis methods.
- Aromatic halide,
- Ortho lithiation,
- Lithium-halogen exchange,
- Mechanism research
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Ortho Lithiation and Lithium-Halogen Exchange of Aromatic Halide

南开大学师唯/华北电力大学（保定）刘景维：二维配位聚合物中有序的亲锂冠醚位点用于无枝晶锂沉积

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通讯作者: 陈斌, bchen63@163.com