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Citation: ZHANG Hong-Gang, CHEN Jian-Hua, LI Sheng-Xiang, REN Xiang-Wei, ZHAO Wen-Tao, ZHANG Wan-Dong. Self-Condensation of Benzaldehyde to Benzyl Benzoate over Sodium Benzyloxide[J]. University Chemistry, ;2016, 31(10): 64-67. doi: 10.3866/PKU.DXHX201601038 shu

Self-Condensation of Benzaldehyde to Benzyl Benzoate over Sodium Benzyloxide

Department of Chemistry, School of Science, Tianjin University, Tianjin 300072, P. R. China

To cultivate students' innovation ability,we designed the synthetic method of benzyl benzoate as an organic chemistry laboratory experiment.Benzyl benzoate was directly synthesized from benzaldehyde in the presence of a sodium benzyloxide via the Tishchenko reaction.The experimental conditions are optimized with a benzaldehyde to sodium benzyloxide mole ratio of 33:1 and a 50-60℃ reaction temperature for 1 h.A yield up to 69% was achieved with the purity higher than 99%.The experimental results show that the process is in accordance with the requirements of organic chemistry laboratory teaching.
- Tishchenko reaction,
- Benzaldehyde,
- Sodium benzyloxide,
- Benzyl benzoate,
- Organic chemistry experiments
1. [1]
2. [2]
3. [3]
4. [4]
5. [5]
6. [6]
7. [7]
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