Citation: XIANG Xiaochao, JIAO Fenglong, ZHANG Yangjun, QIAN Xiaohong, QIN Weijie. Progress in the application of functional materials in proteomics research[J]. Chinese Journal of Chromatography, ;2019, 37(11): 1135-1141. doi: 10.3724/SP.J.1123.2019.04041 shu

Progress in the application of functional materials in proteomics research

Beijing Institute of Lifeomics, Beijing Proteome Research Center, National Center for Protein Sciences(Beijing), State Key Laboratory of Proteomics, Beijing 102206, China

Received Date: 26 April 2019

Fund Project: National Key Program for Basic Research of China (Nos. 2017YFA0505002, 2018YFC0910302, 2016YFA0501403, 2018YFF0212505, 2017YFC0906703).

With the increasing depth of proteomic identification, quantitative accuracy and increasing analytical speed, new challenges are being encountered in the development of proteomics methods. Traditional proteomics methods are time-consuming and have low sensitivity and poor accuracy; hence, they do not satisfy the new demands in proteomics research. Preparation of novel materials with specific functions via chemical and biochemical routes or by methods based on electricity, magnetism, heat, and photoirradiation is the key to overcome the limitations of traditional analytical techniques and promote active research in the field of proteomics. This paper reviews the recent advances in the application of functional materials in proteomics researches.
- functional materials,
- proteomics,
- immobilized enzyme,
- protein post-translational modification,
- transcription factor,
- ¹⁸O labelling,
- review
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