Citation: WANG Xiaofei, SUN Kaiyue, ZHANG Bo. Multi-column technologies in chromatographic analysis[J]. Chinese Journal of Chromatography, ;2019, 37(2): 123-131. doi: 10.3724/SP.J.1123.2018.11023 shu

Multi-column technologies in chromatographic analysis

College of Chemistry & Chemical Engineering, Xiamen University, Xiamen 361005, China

Received Date: 15 November 2018

Fund Project: National Natural Science Foundation of China (Nos. 21475110, 21535007, J1310024)

Multi-column chromatographic technologies provide high throughput and high resolution separations through parallel, serial or parallel-serial column combinations. In comparison with classical single-column based chromatography, multi-column chromatography well satisfied the need for separations of large batch samples and highly complex bio-samples, and therefore attracted extensive interests. In this review, we discussed the recent developments in multi-column chromatography and its applications in multidimensional separation, chip chromatography, capillary electrophoresis, stationary-phase screening, and serial column chromatography. We also discussed the limitations and future developments in multi-column chromatography.
- multi-column chromatography,
- parallel/serial columns,
- high-throughput,
- chip separation,
- multidimensional chromatography,
- review
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