Citation: WU Fei, LÜ Xiaodan, TANG Junjie, CHEN Qixian, PENG Xuetang, CHEN Qidan. Optimization of the extraction method for high performance liquid chromatography analysis of trace di(2-ethylhexyl)phthalate in drinking water by response surface methodology and the migration regularity[J]. Chinese Journal of Chromatography, ;2016, 34(10): 992-997. doi: 10.3724/SP.J.1123.2016.06048 shu

Optimization of the extraction method for high performance liquid chromatography analysis of trace di(2-ethylhexyl)phthalate in drinking water by response surface methodology and the migration regularity

WU Fei ^1,2, ,
LÜ Xiaodan ^1,2 ,
TANG Junjie ^1,2 ,
CHEN Qixian ¹ ,
PENG Xuetang ¹ ,
CHEN Qidan ^1,2

1.
Zhuhai College of Jilin University, Zhuhai 519041, China;
2.
Zhuhai Institute of Supramolecular Materials, Jilin University, Zhuhai 519041, China

Received Date: 29 June 2016

Fund Project: National Natural Science Foundation of China (No. 21307039)

A simple and rapid method for the determination of trace di(2-ethylhexyl)phthalate (DEHP) in drinking water was developed and the migration regularity was studied. In this work, the migration of DEHP from plastic bottle products of supermarket was studied by high performance liquid chromatography coupled with ultraviolet detection (HPLC-UV), and the extraction conditions were optimized by response surface methodology (RSM). With the effect of NaCl, DEHP in drinking water sample was extracted in n-hexane by vortex, dried and concentrated by N₂, and then dissolved by methanol. The filtrate was injected into an HPLC-UV system for the analysis. The optimized extraction conditions were NaCl of 16 g/L, the vortex time of 90 s and the volume of n-hexane of 5.28 mL. Under the optimized conditions, the experimental value and the predicted value of the recoveries of DEHP were 92.97% and 92.91%, respectively, and the difference was only 0.063%. The limit of detection was 0.006 mg/L, the linear range was 0.01-15 mg/L (R=0.9996), and the relative standard deviation (RSD) was 0.015%-2.45%. In addition, the real water sample in plastic bottles from local supermarket was determined by the method and the migration regularity of trace DEHP in drinking water from plastic container under different temperature and time conditions was studied. The results showed that the application of RSM in the selection of optimal conditions for trace analysis is feasible, low-cost and eco-friendly.
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2. [2]
3. [3]
4. [4]
5. [5]
6. [6]
7. [7]
8. [8]
9. [9]
10. [10]
11. [11]
12. [12]
13. [13]
14. [14]
15. [15]
16. [16]
17. [17]
18. [18]
19. [19]
20. [20]
21. [21]
22. [22]
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