Citation: ZHOU Shanshan, ZHAI Rui, JIAO Fenglong, HAO Feiran, LV Yayao, QIAN Xiaohong, ZHANG Yangjun. Progress in preparation of open tubular columns in capillary liquid chromatography and their applications in proteomics studies[J]. Chinese Journal of Chromatography, ;2016, 34(3): 226-231. doi: 10.3724/SP.J.1123.2015.11033 shu

Progress in preparation of open tubular columns in capillary liquid chromatography and their applications in proteomics studies

1.
1. Guangxi Medical University, Nanning 530021, China;
2.
2. State Key Laboratory of Proteomics, Beijing Proteome Research Center, Beijing Institute of Radiation Medicine, Beijing 102206, China

Corresponding author: ZHANG Yangjun,
Received Date: 18 November 2015

Fund Project: 国家重大科学计划项目(2012CB910603) (2012CB910603)国家高技术研究发展规划项目(2012AA020202) (2012AA020202)国家重大科学仪器设备开发专项项目(2012YQ12004407,2011YQ06008408,2013YQ14040506) (2012YQ12004407,2011YQ06008408,2013YQ14040506)国家自然科学基金项目(21275519,20735005,31100591). (21275519,20735005,31100591)

With the further development of life sciences in recent years, the demand for analysis of very small amounts of sample has increased, and more attention has been paid for the miniaturized liquid chromatography system. Longer open tubular capillary columns were selected to increase column efficiency due to their low column back pressure, and they were often used to separate complex biological samples in high resolution. Therefore, they emerged as the new area of liquid chromatography columns. The preparation methods and applications in proteomics of open tubular columns in capillary liquid chromatography (capLC) are reviewed.
- capillary liquid chromatography (capLC),
- open tubular capillary columns,
- porous layer,
- proteomics,
- review
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