Citation: WANG Jing, AI Lianfeng, MA Yusong, ZHANG Haichao, LI Wei, YU Meng. Determination of 213 pesticide residues in milk and milk power by gas chromatography-triple quadrupole tandem mass spectrometry[J]. Chinese Journal of Chromatography, ;2015, 33(11): 1175-1185. doi: 10.3724/SP.J.1123.2015.07012 shu

Determination of 213 pesticide residues in milk and milk power by gas chromatography-triple quadrupole tandem mass spectrometry

WANG Jing ¹ ,
AI Lianfeng ^1,, ,
MA Yusong ¹ ,
ZHANG Haichao ¹ ,
LI Wei ¹ ,
YU Meng ²

1.
1. Hebei Entry-Exit Inspection and Quarantine Bureau, Shijiazhuang 050051, China;

Corresponding author: AI Lianfeng,
Received Date: 10 July 2015

Fund Project: 国家质检总局科技计划项目(2013IK154) (2013IK154)河北检验检疫局科研项目(HE2014K018). (HE2014K018)

On the basis of the optimization of solid phase extraction adsorbent, eluting solvent types and amounts, a gas chromatography-triple quadrupole tandem mass spectrometry (GC-MS/MS) method was established for the determination of 213 pesticide residues in milk and milk power. The samples were extracted by acetonitrile, cleaned-up with an ENVI-Carb/NH₂ solid-phase extractant, and determined by GC-MS/MS using external standard method. The linear ranges were from 10 to 1000 μ g/L for 197 pesticides, from 50 to 1000 μ g/L for the other 16 pesticides with the correlation coefficients higher than 0.99. The limits of detection (LODs, S/N=3) varied over the range of 0.03 to 7.59 μ g/kg, and limits of quantification (LOQs, S/N=10) ranged from 0.10 to 21.94 μ g/kg. The average recoveries in different matrices were in the range of 66.9%-120.1% with the relative standard deviations (RSDs) of 1.23%-17.6%. This method is simple, rapid, sensitive and reliable for meeting the requirements for the simultaneous identification and quantification of the multi-residues in milk and milk power.
- gas chromatography-triple quadrupole tandem mass spectrometry (GC-MS/MS),
- pesticide residues,
- milk,
- milk power
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