Citation: LI Xiaomin, WANG Jing, ZHANG Qinghe, LI Hongmei. Advances on the development of detection methods for the phthalate esters in food[J]. Chinese Journal of Chromatography, ;2015, 33(11): 1147-1154. doi: 10.3724/SP.J.1123.2015.06027 shu

Advances on the development of detection methods for the phthalate esters in food

LI Xiaomin ¹ ,
WANG Jing ^1,2 ,
ZHANG Qinghe ^1,, ,
LI Hongmei ¹

1.
1. Division of Chemical Metrology and Analytical Science, National Institute of Metrology, Beijing 100029, China;

Corresponding author: ZHANG Qinghe,
Received Date: 17 June 2015

Fund Project: 科技部科学仪器开发重大专项项目(2012YQ09016703). (2012YQ09016703)

Phthalate esters are most widely used as plasticizers which have toxicity and carcinogenicity. Phthalate esters are found as contaminants in many food products and they are a branch of compounds, homologues and isomers, which present similar structures and properties. And the residue contents vary a lot in different matrices. Efficient sample pretreatment, highly selective separation mode, sensitive detection methods as well as reducing background interference are challenges for their determination in complex samples. In this paper, some sample pretreatment methods such as liquid-liquid extraction, liquid-liquid micro-extraction, solid phase extraction, solid phase micro-extraction, matrix solid-phase extraction and other traditional and new types of extraction and purification technology applied in the food samples are reviewed. The characteristics of analytical methods including gas chromatography, liquid chromatography, tandem mass spectrometry, high resolution mass spectrometry, enzyme-linked immunoassay, and ion mobility spectrometry are also discussed.
- phthalate esters,
- food,
- sample pretreatment,
- analytical methods
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