Citation: LI Xiaomin, WANG Jing, ZHANG Qinghe, LI Hongmei. Advances on the development of detection methods for the phthalate esters in food[J]. Chinese Journal of Chromatography, ;2015, 33(11): 1147-1154. doi: 10.3724/SP.J.1123.2015.06027 shu

Advances on the development of detection methods for the phthalate esters in food

LI Xiaomin ¹ ,
WANG Jing ^1,2 ,
ZHANG Qinghe ^1,, ,
LI Hongmei ¹

1.
1. Division of Chemical Metrology and Analytical Science, National Institute of Metrology, Beijing 100029, China;

Corresponding author: ZHANG Qinghe,
Received Date: 17 June 2015

Fund Project: 科技部科学仪器开发重大专项项目(2012YQ09016703). (2012YQ09016703)

Phthalate esters are most widely used as plasticizers which have toxicity and carcinogenicity. Phthalate esters are found as contaminants in many food products and they are a branch of compounds, homologues and isomers, which present similar structures and properties. And the residue contents vary a lot in different matrices. Efficient sample pretreatment, highly selective separation mode, sensitive detection methods as well as reducing background interference are challenges for their determination in complex samples. In this paper, some sample pretreatment methods such as liquid-liquid extraction, liquid-liquid micro-extraction, solid phase extraction, solid phase micro-extraction, matrix solid-phase extraction and other traditional and new types of extraction and purification technology applied in the food samples are reviewed. The characteristics of analytical methods including gas chromatography, liquid chromatography, tandem mass spectrometry, high resolution mass spectrometry, enzyme-linked immunoassay, and ion mobility spectrometry are also discussed.
- phthalate esters,
- food,
- sample pretreatment,
- analytical methods
1. [1]
  [1] Tyl R W, Myers C B, Marr M C, et al. Reprod Toxicol, 2004, 18: 241
2. [2]
  [2] Wine R N, Li L H, Barnes L H, et al. Environ Health Perspect, 1997, 105: 102
3. [3]
  [3] US Department of Health and Human Services. National Toxicology Program (NTP) Technical Report Series No. 217, 1982
4. [4]
  [4] Kamrin M A. J Toxicol Environ Health, 2009, 12: 157
5. [5]
  [5] Yang Y Y, Xie Y F, Tian F F, et al. Chinese Journal of Chromatography (杨悠悠, 谢云峰, 田菲菲, 等. 色谱), 2013, 31(7): 674
6. [6]
  [6] Zhou J H, Qi Y T, Wu H M, et al. J Sep Sci, 2014, 37: 650
7. [7]
  [7] Wang J, Li X M, Zhang Q H, et al. J Sep Sci, 2015, 38: 1700
8. [8]
  [8] Zhu W X, Yang J Z, Yuan P, et al. Modern Food Science and Technology (祝伟霞, 杨冀州, 袁萍, 等. 现代食品科技), 2012, 28(1): 115
9. [9]
  [9] Rezaee M, Assadi Y, Hosseini M M, et al. J Chromatogr A, 2006, 1116(1/2): 1
10. [10]
  [10] Leng G, Chen W J, Zhang M F, et al. J Sep Sci, 2014, 37: 684
11. [11]
  [11] Cinelli G, Avino P, Notardonato I, et al. Anal Chim Acta, 2013, 769: 72
12. [12]
  [12] Fan J C, Wu L, Wang X F, et al. Anal Methods, 2012, 4: 4168
13. [13]
  [13] Zheng X H, Lin L Y, Fang E H, et al. Chinese Journal of Chromatography (郑向华, 林立毅, 方恩华, 等. 色谱), 2012, 30(1): 27
14. [14]
  [14] Guo Z Y, Wang S, Wei D Y, et al. Meat Sci, 2010, 84: 484
15. [15]
  [15] Ierapetritis I, Lioupis A, Lampi E. Food Anal Methods, 2014, 7: 1451
16. [16]
  [16] Li Y J, Xiong W M, Chen J W, et al. Journal of Instrumental Analysis (李拥军, 熊文明, 陈坚文, 等. 分析测试学报), 2012, 31(3): 278
17. [17]
  [17] Zhang F, Li Z H, Zhang Y, et al. Chinese Journal of Chromatography (张帆, 李忠海, 张莹, 等. 色谱), 2014, 32(7): 735
18. [18]
  [18] Del Carlo M, Pepe A, Sacchetti G, et al. Food Chem, 2008, 111: 771
19. [19]
  [19] Wu P, Yang D, Zhang L, et al. J Sep Sci, 2012, 35(21): 2932
20. [20]
  [20] Carrillo J D, Salazar C, Moreta C, et al. J Chromatogr A, 2007, 1164: 248
21. [21]
  [21] Li J, Su Q, Li K Y, et al. Food Chem, 2013, 141: 3714
22. [22]
  [22] Ye C W, Gao J, Yang C, et al. Anal Chim Acta, 2009, 641: 64
23. [23]
  [23] Zhang C Y, Wang H, Zhang X H, et al. Chinese Journal of Chromatography (张春雨, 王辉, 张晓辉, 等. 色谱), 2011, 29(12): 1236
24. [24]
  [24] Zhang H J, Zhang J X, Li H, et al. Food Science (张会军, 张敬轩, 李挥, 等. 食品科学), 2011, 32(4): 152
25. [25]
  [25] Wang M L, Kou L J, Zhang Y Q, et al. Chinese Journal of Chromatography (王明林, 寇丽娟, 张玉倩, 等. 色谱), 2007, 25(4): 577
26. [26]
  [26] Deng L, Hao X C. Chinese Journal of Analytical Chemistry (邓莉, 郝学财. 分析化学), 2013, 41(7): 1037
27. [27]
  [27] Sun X, Qi L, Qin Y T, et al. Chinese Journal of Chromatography (孙欣, 齐莉, 秦延亭, 等. 色谱), 2014, 32(11): 1260
28. [28]
  [28] Wang M F, Hu E Y, Yang L L, et al. Chemical Analysis and Meterage (王美飞, 胡恩宇, 杨丽莉, 等. 化学分析计量), 2015, 24(1): 94
29. [29]
  [29] GB/T 21911-2008
30. [30]
  [30] Cavaliere B, Macchione B, Sindona G, et al. J Chromatogr A, 2008, 1205: 137
31. [31]
  [31] Carrillo J D, Martínez M P, Tena M T. J Chromatogr A, 2008, 1181: 125
32. [32]
  [32] Cao Y, Yin X Y, Zhou F Q, et al. Chinese Journal of Analytical Chemistry (曹阳, 殷雪琰, 周方晴, 等. 分析化学), 2013, 41(12): 1837
33. [33]
  [33] Xu D M, Deng X J, Fang E H, et al. J Chromatogr A, 2014, 1324: 49
34. [34]
  [34] Chen D W, Zhao X X, Zhao Y F, et al. Journal of Food Safety and Quality (陈达炜, 赵晓雪, 赵云峰, 等. 食品安全质量检测学报), 2014, 5(9): 2640
35. [35]
  [35] Wang X B, Ding L, Zhu S H, et al. Packaging Engineering (王晓兵, 丁利, 朱绍华, 等. 包装工程), 2011, 32(15): 43
36. [36]
  [36] Zhang H J, Hu X J, Lin S B. Chinese Journal of Analytical Chemistry (张海婧, 胡小键, 林少彬. 分析化学), 2014, 42(9): 1281
37. [37]
  [37] Li H Y, Shi Y T, Zeng Q F. Industrial Water Treatment (李海燕, 施银桃, 曾庆福. 工业水处理), 2004, 24(8): 55
38. [38]
  [38] Zhang M C, Cong Y, Sheng Y L, et al. Anal Biochem, 2011, 406(1): 24
39. [39]
  [39] Zhang M C, Wang Y, Yu X N, et al. Food Agr Immunol, 2014, 25(2): 229
40. [40]
  [40] Zhang M C, Yu X N, Wang Y, et al. Food Anal Methods, 2013, 6(4): 1223
41. [41]
  [41] Peng L Y, Wang W G, Wang X, et al. Chinese Journal of Analytical Chemistry (彭丽英, 王卫国, 王新, 等. 分析化学), 2014, 42(2): 287
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