Citation: MU Xiaoyu, QI Li, SU Yuan, QIAO Juan, CHEN Yi. Development of chiral ligand exchange capillary electrophoresis for enantioseparation of D,L-amino acids[J]. Chinese Journal of Chromatography, ;2016, 34(1): 21-27. doi: 10.3724/SP.J.1123.2015.05038 shu

Development of chiral ligand exchange capillary electrophoresis for enantioseparation of D,L-amino acids

MU Xiaoyu ^1,2 ,
QI Li ^1,, ,
SU Yuan ^1,3 ,
QIAO Juan ¹ ,
CHEN Yi ¹

1.
1. Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China;
2.
2. University of Chinese Academy of Sciences, Beijing 100049, China;
3.
3. Shandong Agricultural University, Taian 271018, China

Corresponding author: QI Li,
Received Date: 28 May 2015

Fund Project: 国家自然科学基金项目(21175138,21321003). (21175138,21321003)

Enantioseparation of D,L-amino acids is of great significance in life science. As one of the most useful methods, chiral ligand exchange capillary electrophoresis possesses many advantages, including high efficiency, fast speed and tunable migration order, and it has attracted great research interest. This review summarizes the development of chiral ligand exchange capillary electrophoresis for enantioseparation of D,L-amino acids in recent years.
- chiral ligand exchange capillary electrophoresis (CLE-CE),
- D,L-amino acids,
- enantioseparation,
- review
1. [1]
  [1] Myrgorodska I, Meinert C, Martins Z, et al. Angew Chem Int Edit, 2015, 54: 1402
2. [2]
  [2] Giuffrida A, Maccarrone G, Cucinotta V, et al. J Chromatogr A, 2014, 1363: 41
3. [3]
  [3] Davankov V A, Rogozhin S V. J Chromatogr, 1971, 60: 280
4. [4]
  [4] Gassmann E, Kuo J E, Zare R N. Science, 1985, 230: 813
5. [5]
  [5] Yuan Z B, Yang L L, Zhang S S. Electrophoresis, 1999, 20: 1842
6. [6]
  [6] Lu X N, Chen Y, Guo L, et al. J Chromatogr A, 2002, 945: 249
7. [7]
  [7] Lecnik O, Schmid M G, Presser A, et al. Electrophoresis, 2002, 23: 3006
8. [8]
  [8] Zheng Z X, Lin J M, Qu F. J Chromatogr A, 2003, 1007: 189
9. [9]
  [9] Zheng Z X, Wei Y L, Lin J M. Electrophoresis, 2004, 25: 1007
10. [10]
  [10] Zhao Y F, Zhao L, Ming Y F, et al. Chinese Journal of Analytical Chemistry, 2006, 34(Special): S87 赵艳芳, 赵亮, 明永飞, 等. 分析化学, 2006, 34(特刊): S87
11. [11]
  [11] Mohr S, Hägele J S, Schmid M G. Croat Chem Acta, 2011, 84: 343
12. [12]
  [12] Qi L, Liu M R, Guo Z P, et al. Electrophoresis, 2007, 28: 4150
13. [13]
  [13] Qi L, Han Y L, Zuo M, et al. Electrophoresis, 2007, 28: 262
14. [14]
  [14] Qi L, Qiao J, Yang G L, et al. Electrophoresis, 2009, 30: 2266
15. [15]
  [15] Zheng Z X, Qu F, Lin J M. Chin J Chem, 2003, 21: 1478
16. [16]
  [16] Qi L, Yang G L, Zhang H Z, et al. Talanta, 2010, 81: 1554
17. [17]
  [17] Sun B B, Qi L, Mu X Y, et al. Talanta, 2013, 116: 1121
18. [18]
  [18] Su Y, Mu X Y, Qi L. RSC Adv, 2014, 4: 55280
19. [19]
  [19] Chen Z L, Niitsuma M, Nakagama T, et al. J Sep Sci, 2002, 25: 1197
20. [20]
  [20] Chen Z L, Niitsuma M, Uchiyama K, et al. J Chromatogr A, 2003, 990: 75
21. [21]
  [21] Chen Z L, Uchiyama K, Hobo T. Anal Chim Acta, 2004, 523: 1
22. [22]
  [22] Zhang H Z, Qi L, Lin Y Q, et al. Amino Acids, 2012, 42: 337
23. [23]
  [23] Zhang H Z, Qi L, Qiao J, et al. Anal Chim Acta, 2011, 691: 103
24. [24]
  [24] Fukumoto K, Yoshizawa M, Ohno H. J Am Chem Soc, 2005, 127: 2398
25. [25]
  [25] Tao G H, He L, Sun N, et al. Chem Commun, 2005: 3562
26. [26]
  [26] Liu Q, Wu K K, Tang F, et al. Chem Eur J, 2009, 15: 9889
27. [27]
  [27] Liu R J, Du Y X, Chen J Q, et al. Chirality, 2015, 27: 58
28. [28]
  [28] Mu X Y, Qi L, Shen Y, et al. Analyst, 2012, 137: 4235
29. [29]
  [29] Mu X Y, Qiao J, Qi L, et al. ACS Appl Mater Interfaces, 2014, 6: 21346
30. [30]
  [30] Mu X Y, Qiao J, Qi L, et al. ACS Appl Mater Interfaces, 2014, 6: 12979
31. [31]
  [31] Zhang H Z, Qi L, Shen Y, et al. Electrophoresis, 2013, 34: 846
32. [32]
  [32] Sun B B, Mu X Y, Qi L. Anal Chim Acta, 2014, 821: 97
33. [33]
  [33] Mu X Y, Qi L, Zhang H Z, et al. Talanta, 2012, 97: 349
34. [34]
  [34] Végvári Á, Schmid M G, Kilár F, et al. Electrophoresis, 1998, 19: 2109
35. [35]
  [35] Schmid M G, Rinaldi R, Dreveny D, et al. J Chromatogr A, 1999, 846: 157
36. [36]
  [36] Mu X Y, Qi L, Qiao J, et al. Anal Chim Acta, 2014, 846: 68
37. [37]
  [37] Gozel P, Gassmann E, Michelsen H, et al. Anal Chem, 1987, 59: 44
38. [38]
  [38] Hödl H, Schmid M G, Gübitz G. J Chromatogr A, 2008, 1204: 210
39. [39]
  [39] Sundin N G, Dowling T M, Grinberg N, et al. J Microcolumn Sep, 1996, 8: 323
40. [40]
  [40] Chen Z L, Lin J M, Uchiyama K, et al. J Microcolumn Sep, 1999, 11: 534
41. [41]
  [41] Chen Z L, Lin J M, Uchiyama K, et al. J Chromatogr A, 1998, 813: 369
42. [42]
  [42] Chen Z L, Lin J M, Uchiyama K, et al. Anal Sci, 2000, 16: 131
43. [43]
  [43] Zheng Z X, Lin J M, Huie C W. Chinese Journal of Chromatography, 2004, 22(4): 309 郑志侠, 林金明, Huie C W. 色谱, 2004, 22(4): 309
44. [44]
  [44] Schmid M G, Grobuschek N, Tuscher C, et al. Electrophoresis, 2000, 21: 3141
45. [45]
  [45] Chen Z L, Hobo T. Anal Chem, 2001, 73: 3348
46. [46]
  [46] Nishiyama T, Chen Z L, Nakagama T, et al. Bunseki Kagaku, 2003, 52: 1005
47. [47]
  [47] Pittler E, Grawatsch N, Paul D, et al. Electrophoresis, 2009, 30: 2897
48. [48]
  [48] Su Y, Mu X Y, Qi L. RSC Adv, 2015, 5: 28762
1. [1]
  Keying Qu , Jie Li , Ziqiu Lai , Kai Chen . Unveiling the Mystery of Chirality from Tartaric Acid. University Chemistry, 2024, 39(9): 369-378. doi: 10.12461/PKU.DXHX202310091
2. [2]
  Dongheng WANG , Si LI , Shuangquan ZANG . Construction of chiral alkynyl silver chains and modulation of chiral optical properties. Chinese Journal of Inorganic Chemistry, 2025, 41(1): 131-140. doi: 10.11862/CJIC.20240379
3. [3]
  Jin Tong , Shuyan Yu . Crystal Engineering for Supramolecular Chirality. University Chemistry, 2024, 39(3): 86-93. doi: 10.3866/PKU.DXHX202308113
4. [4]
  Conghao Shi , Ranran Wang , Juli Jiang , Leyong Wang . The Illustration on Stereoisomers of Macrocycles Containing Multiple Chiral Centers via Tröger Base-based Macrocycles. University Chemistry, 2024, 39(7): 394-397. doi: 10.3866/PKU.DXHX202311034
5. [5]
  Renxiao Liang , Zhe Zhong , Zhangling Jin , Lijuan Shi , Yixia Jia . A Palladium/Chiral Phosphoric Acid Relay Catalysis for the One-Pot Three-Step Synthesis of Chiral Tetrahydroquinoline. University Chemistry, 2024, 39(5): 209-217. doi: 10.3866/PKU.DXHX202311024
6. [6]
  Haiying Wang , Andrew C.-H. Sue . How to Visually Identify Homochiral Crystals. University Chemistry, 2024, 39(3): 78-85. doi: 10.3866/PKU.DXHX202309004
7. [7]
  Xilin Zhao , Xingyu Tu , Zongxuan Li , Rui Dong , Bo Jiang , Zhiwei Miao . Research Progress in Enantioselective Synthesis of Axial Chiral Compounds. University Chemistry, 2024, 39(11): 158-173. doi: 10.12461/PKU.DXHX202403106
8. [8]
  Ke QIAO , Yanlin LI , Shengli HUANG , Guoyu YANG . Advancements in asymmetric catalysis employing chiral iridium (ruthenium) complexes. Chinese Journal of Inorganic Chemistry, 2024, 40(11): 2091-2104. doi: 10.11862/CJIC.20240265
9. [9]
  Tingyu Zhu , Hui Zhang , Wenwei Zhang . Exploration and Practice of Ideological and Political Education in the Course of Experiments on Chemical Functional Molecules: Synthesis and Catalytic Performance Study of Chiral Mn(III)Cl-Salen Complex. University Chemistry, 2024, 39(4): 75-80. doi: 10.3866/PKU.DXHX202311011
10. [10]
  Yan Li , Xinze Wang , Xue Yao , Shouyun Yu . 基于激发态手性铜催化的烯烃E→Z异构的动力学拆分——推荐一个本科生综合化学实验. University Chemistry, 2024, 39(5): 1-10. doi: 10.3866/PKU.DXHX202309053
11. [11]
  .
  CCS Chemistry 综述推荐│绿色氧化新思路：光/电催化助力有机物高效升级
  . CCS Chemistry, 2025, 7(10.31635/ccschem.024.202405369): -.
12. [12]
  Hong CAI , Jiewen WU , Jingyun LI , Lixian CHEN , Siqi XIAO , Dan LI . Synthesis of a zinc-cobalt bimetallic adenine metal-organic framework for the recognition of sulfur-containing amino acids. Chinese Journal of Inorganic Chemistry, 2025, 41(1): 114-122. doi: 10.11862/CJIC.20240382
13. [13]
  Liwei Wang , Guangran Ma , Li Wang , Fugang Xu . A Comprehensive Analytical Chemistry Experiment: Colorimetric Detection of Vitamin C Using Nanozyme and Smartphone. University Chemistry, 2024, 39(8): 255-262. doi: 10.3866/PKU.DXHX202312094
14. [14]
  Li'na ZHONG , Jingling CHEN , Qinghua ZHAO . Synthesis of multi-responsive carbon quantum dots from green carbon sources for detection of iron ions and L-ascorbic acid. Chinese Journal of Inorganic Chemistry, 2025, 41(4): 709-718. doi: 10.11862/CJIC.20240280
15. [15]
  Lei Shi . Nucleophilicity and Electrophilicity of Radicals. University Chemistry, 2024, 39(11): 131-135. doi: 10.3866/PKU.DXHX202402018
16. [16]
  Yumiao Gao , Yixin Chen , Jiaxin Wei , Junjie Yu , Yunxia Wang . Guarding the Kingdom: Skin Allies with Sunscreen for Mutual Protection. University Chemistry, 2024, 39(9): 74-80. doi: 10.12461/PKU.DXHX202404149
17. [17]
  Tao Yang , Kaijiao Duan , Siyu Li , Jing Wei , Qingdi Yang , Qian Wang . A Comprehensive and Innovative Chemical Experimental Teaching: Extraction and Identification of Tea Polyphenols from Pu'er Tea and the Application in Hand Cream Making. University Chemistry, 2024, 39(8): 270-275. doi: 10.3866/PKU.DXHX202312040
18. [18]
  Peiran ZHAO , Yuqian LIU , Cheng HE , Chunying DUAN . A functionalized Eu³⁺ metal-organic framework for selective fluorescent detection of pyrene. Chinese Journal of Inorganic Chemistry, 2024, 40(4): 713-724. doi: 10.11862/CJIC.20230355
19. [19]
  Ping Cai , Yaxian Zhu , Tao Hu . Frontier Research and Basic Theory in the Classroom: an Introduction to the Inorganic Chemistry Teaching Case under the Chemistry “101 Plan”. University Chemistry, 2024, 39(10): 84-88. doi: 10.12461/PKU.DXHX202408027
20. [20]
  Jun LUO , Baoshu LIU , Yunchang ZHANG , Bingkai WANG , Beibei GUO , Lan SHE , Tianheng CHEN . Europium(Ⅲ) metal-organic framework as a fluorescent probe for selectively and sensitively sensing Pb²⁺ in aqueous solution. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2438-2444. doi: 10.11862/CJIC.20240240

Get Citation

PDF

XML

Metrics

PDF Downloads(6)
Abstract views(235)
HTML views(29)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142