Citation: CHEN Langxing, LIU Yuxing, HE Xiwen, ZHANG Yukui. Preparation and characterization of core-shell structural magnetic molecularly imprinted polymers for nafcillin[J]. Chinese Journal of Chromatography, ;2015, 33(5): 481-487. doi: 10.3724/SP.J.1123.2014.12040 shu

Preparation and characterization of core-shell structural magnetic molecularly imprinted polymers for nafcillin

CHEN Langxing ^1,, ,
LIU Yuxing ¹ ,
HE Xiwen ¹ ,
ZHANG Yukui ^1,2

1.
1. College of Chemistry, Research Center for Analytical Sciences, Nankai University, Tianjin 300071, China;

Corresponding author: CHEN Langxing,
Received Date: 30 December 2014

Fund Project: 国家重点基础研究发展规划("973"计划)项目(2012CB910601) ("973"计划)项目(2012CB910601)国家自然科学基金项目(21275080) (21275080)高等学校博士学科点专项科研基金项目(20120031110007). (20120031110007)

The uniform core-shell nanostructured magnetic molecularly imprinted polymers (MIPs) were synthesized using antibiotic nafcillin as a template. In this protocol, the magnetite nanoparticles (NPs) were synthesized by the solvothermal reaction firstly. Subsequently, the vinyl groups were grated onto silica-modified Fe₃O₄ surface by 3-methacryloyloxypropyltrimethoxysilane via sol-gel method. Finally, the nafcillin-MIPs film was formed on the surface of Fe₃O₄@SiO₂ by the copolymerization of vinyl end group with functional monomer, methacrylic acid, cross-linking agent, ethylene glycol dimethacrylate, the initiator azo-bis-isobutyronitrile and template molecule. The morphological and magnetic characteristics of the MIPs were characterized by transmission electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction and vibrating sample magnetometer. The obtained spherical magnetic MIPs with diameters of about 320 nm had good monodispersity. The static binding experiment was carried out to evaluate the properties of magnetic MIPs and non imprinted polymers (NIPs). The results demonstrated that the magnetic MIPs had high adsorption capacity to template and good selectivity. The imprinting factor and the maximum adsorption capacity of Fe₃O₄@MIPs to nafcillin were 2.46 and 50.7 mg/g, respectively. It is expected that the prepared magnetic MIPs could be used for the enrichment of nafcillin in complex samples.
- molecularly imprinted polymers (MIPs),
- magnetic microspheres,
- nafcillin,
- enrichment
1. [1]
  [1] Niu Z Q, Zheng M. China Animal Health (牛志强, 郑敏. 中国动物保健), 2009(6): 63
2. [2]
  [2] Bogialli S, Capitolino V, Curini R, et al. J Agric Food Chem, 2004, 52(11): 3286
3. [3]
  [3] Benito-Pena E, Partal-Rodera A I, León-González M E, et al. Anal Chim Acta, 2006, 556(2): 415
4. [4]
  [4] Cha J M, Yang S, Carlson K H. J Chromatogr A, 2006, 1115(1/2): 45
5. [5]
  [5] Denooz R, Charlier C. J Chromatogr B, 2008, 864(1/2): 161
6. [6]
  [6] Riediker S, Stadler R H. Anal Chem, 2001, 73(7): 1614
7. [7]
  [7] Bailón-Pérez M I, Garcia-Campana A M, del Olmo Iruela M D, et al. Electrophoresis, 2009, 30(10): 1708
8. [8]
  [8] Pawliszyn J. Comprehensive Sampling and Sample Preparation Analytical Techniques for Scientist, Volume 4: Extraction Techniques and Applications: Food and Beverage. Amsterdam: Academic Press, 2012
9. [9]
  [9] Pan M F, Wang J P, Fang G Z, et al. J Chromatogr B, 2010, 878(19): 1531
10. [10]
  [10] Sun X L, He X W, Zhang Y K, et al. Talanta, 2009, 79(3): 926
11. [11]
  [11] Puoci F, Curcio M, Cirillo G, et al. Food Chem, 2008, 106(2): 836
12. [12]
  [12] Tamayo F G, Turiel E, Martín-Esteban A. J Chromatogr A, 2007, 1152(1/2): 32
13. [13]
  [13] Yan M, Ramstrom O. Molecularly Imprinted Materials-Science and Technology. New York: Marcel Dekker, 2005
14. [14]
  [14] Chen L X, Xu S F, Li J H. Chem Soc Rev, 2011, 40: 2922
15. [15]
  [15] Gao D M, Zhang Z P, Wu M H, et al. J Am Chem Soc, 2007, 129(25): 7859
16. [16]
  [16] Lu C H, Zhou W H, Han B, et al. Anal Chem, 2007, 79(14): 5457
17. [17]
  [17] Lu F G, Li H J, Sun M, et al. Anal Chim Acta, 2012, 718: 84
18. [18]
  [18] Li X J, Zhang B L, Li W. Biosens Bioelectron, 2014, 51: 261
19. [19]
  [19] Wang X, Wang L Y, He X W, et al. Talanta, 2009, 78: 327
20. [20]
  [20] Li L, He X W, Chen L X, et al. Sci China Ser B-Chem, 2009, 52(9): 1402
21. [21]
  [21] Gao R X, Kong X, Wang X, et al. J Mater Chem, 2011, 21: 17863
22. [22]
  [22] Deng H, Li X L, Peng Q, et al. Angew Chem Int Ed, 2005, 44: 2782
23. [23]
  [23] Yi D K, Lee S S, Ying J Y. Chem Mater, 2006, 18(10): 2459
24. [24]
  [24] Zhou J, He X W. Anal Chim Acta, 1999, 381(1): 85
25. [25]
  [25] Han D M, Fang G Z, Yan X P. J Chromatogr A, 2005, 1100(2): 131
1. [1]
  Junjie Zhang , Yue Wang , Qiuhan Wu , Ruquan Shen , Han Liu , Xinhua Duan . Preparation and Selective Separation of Lightweight Magnetic Molecularly Imprinted Polymers for Trace Tetracycline Detection in Milk. University Chemistry, 2024, 39(5): 251-257. doi: 10.3866/PKU.DXHX202311084
2. [2]
  Zhicheng JU , Wenxuan FU , Baoyan WANG , Ao LUO , Jiangmin JIANG , Yueli SHI , Yongli CUI . MOF-derived nickel-cobalt bimetallic sulfide microspheres coated by carbon: Preparation and long cycling performance for sodium storage. Chinese Journal of Inorganic Chemistry, 2025, 41(4): 661-674. doi: 10.11862/CJIC.20240363
3. [3]
  Zhongxin YU , Wei SONG , Yang LIU , Yuxue DING , Fanhao MENG , Shuju WANG , Lixin YOU . Fluorescence sensing on chlortetracycline of a Zn-coordination polymer based on mixed ligands. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2415-2421. doi: 10.11862/CJIC.20240304
4. [4]
  Bao Jia , Yunzhe Ke , Shiyue Sun , Dongxue Yu , Ying Liu , Shuaishuai Ding . Innovative Experimental Teaching for the Preparation and Modification of Conductive Organic Polymer Thin Films in Undergraduate Courses. University Chemistry, 2024, 39(10): 271-282. doi: 10.12461/PKU.DXHX202404121
5. [5]
  Xiao SANG , Qi LIU , Jianping LANG . Synthesis, structure, and fluorescence properties of Zn(Ⅱ) coordination polymers containing tetra-alkenylpyridine ligands. Chinese Journal of Inorganic Chemistry, 2024, 40(11): 2124-2132. doi: 10.11862/CJIC.20240158
6. [6]
  Xingchao Zhao , Xiaoming Li , Ming Liu , Zijin Zhao , Kaixuan Yang , Pengtian Liu , Haolan Zhang , Jintai Li , Xiaoling Ma , Qi Yao , Yanming Sun , Fujun Zhang . 倍增型全聚合物光电探测器及其在光电容积描记传感器上的应用. Acta Physico-Chimica Sinica, 2025, 41(1): 2311021-. doi: 10.3866/PKU.WHXB202311021
7. [7]
  Xiutao Xu , Chunfeng Shao , Jinfeng Zhang , Zhongliao Wang , Kai Dai . Rational Design of S-Scheme CeO₂/Bi₂MoO₆ Microsphere Heterojunction for Efficient Photocatalytic CO₂ Reduction. Acta Physico-Chimica Sinica, 2024, 40(10): 2309031-. doi: 10.3866/PKU.WHXB202309031
8. [8]
  You Wu , Chang Cheng , Kezhen Qi , Bei Cheng , Jianjun Zhang , Jiaguo Yu , Liuyang Zhang . ZnO/D-A共轭聚合物S型异质结高效光催化产H₂O₂及其电荷转移动力学研究. Acta Physico-Chimica Sinica, 2024, 40(11): 2406027-. doi: 10.3866/PKU.WHXB202406027
9. [9]
  .
  南开大学师唯/华北电力大学（保定）刘景维：二维配位聚合物中有序的亲锂冠醚位点用于无枝晶锂沉积
  . CCS Chemistry, 2025, 7(0): -.
10. [10]
  Jing WU , Puzhen HUI , Huilin ZHENG , Pingchuan YUAN , Chunfei WANG , Hui WANG , Xiaoxia GU . Synthesis, crystal structures, and antitumor activities of transition metal complexes incorporating a naphthol-aldehyde Schiff base ligand. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2422-2428. doi: 10.11862/CJIC.20240278
11. [11]
  Xin MA , Ya SUN , Na SUN , Qian KANG , Jiajia ZHANG , Ruitao ZHU , Xiaoli GAO . A Tb₂ complex based on polydentate Schiff base: Crystal structure, fluorescence properties, and biological activity. Chinese Journal of Inorganic Chemistry, 2024, 40(7): 1347-1356. doi: 10.11862/CJIC.20230357
12. [12]
  Yihao Zhao , Jitian Rao , Jie Han . Synthesis and Photochromic Properties of 3,3-Diphenyl-3H-Naphthopyran: Design and Teaching Practice of a Comprehensive Organic Experiment. University Chemistry, 2024, 39(10): 149-155. doi: 10.3866/PKU.DXHX202402050
13. [13]
  Zhaoyang WANG , Chun YANG , Yaoyao Song , Na HAN , Xiaomeng LIU , Qinglun WANG . Lanthanide(Ⅲ) complexes derived from 4′-(2-pyridyl)-2, 2′∶6′, 2″-terpyridine: Crystal structures, fluorescent and magnetic properties. Chinese Journal of Inorganic Chemistry, 2024, 40(8): 1442-1451. doi: 10.11862/CJIC.20240114
14. [14]
  Yuanpei ZHANG , Jiahong WANG , Jinming HUANG , Zhi HU . Preparation of magnetic mesoporous carbon loaded nano zero-valent iron for removal of Cr(Ⅲ) organic complexes from high-salt wastewater. Chinese Journal of Inorganic Chemistry, 2024, 40(9): 1731-1742. doi: 10.11862/CJIC.20240077
15. [15]
  Jiarong Feng , Yejie Duan , Chu Chu , Dezhen Xie , Qiu'e Cao , Peng Liu . Preparation and Application of a Streptomycin Molecularly Imprinted Electrochemical Sensor: A Suggested Comprehensive Analytical Chemical Experiment. University Chemistry, 2024, 39(8): 295-305. doi: 10.3866/PKU.DXHX202401016
16. [16]
  Changjun You , Chunchun Wang , Mingjie Cai , Yanping Liu , Baikang Zhu , Shijie Li . 引入内建电场强化BiOBr/C₃N₅ S型异质结中光载流子分离以实现高效催化降解微污染物. Acta Physico-Chimica Sinica, 2024, 40(11): 2407014-. doi: 10.3866/PKU.WHXB202407014
17. [17]
  Jie ZHAO , Sen LIU , Qikang YIN , Xiaoqing LU , Zhaojie WANG . Theoretical calculation of selective adsorption and separation of CO₂ by alkali metal modified naphthalene/naphthalenediyne. Chinese Journal of Inorganic Chemistry, 2024, 40(3): 515-522. doi: 10.11862/CJIC.20230385
18. [18]
  Guimin ZHANG , Wenjuan MA , Wenqiang DING , Zhengyi FU . Synthesis and catalytic properties of hollow AgPd bimetallic nanospheres. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 963-971. doi: 10.11862/CJIC.20230293
19. [19]
  Gaofeng Zeng , Shuyu Liu , Manle Jiang , Yu Wang , Ping Xu , Lei Wang . Micro/Nanorobots for Pollution Detection and Toxic Removal. University Chemistry, 2024, 39(9): 229-234. doi: 10.12461/PKU.DXHX202311055
20. [20]
  Yongzhi LI , Han ZHANG , Gangding WANG , Yanwei SUI , Lei HOU , Yaoyu WANG . A two-dimensional metal-organic framework for the determination of nitrofurantoin and nitrofurazone in aqueous solution. Chinese Journal of Inorganic Chemistry, 2025, 41(2): 245-253. doi: 10.11862/CJIC.20240307

Get Citation

PDF

XML

Metrics

PDF Downloads(0)
Abstract views(299)
HTML views(5)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Preparation and characterization of core-shell structural magnetic molecularly imprinted polymers for nafcillin

南开大学师唯/华北电力大学（保定）刘景维：二维配位聚合物中有序的亲锂冠醚位点用于无枝晶锂沉积

Metrics

通讯作者: 陈斌, bchen63@163.com