Citation: ZHU Pingping, YUE Zhenfeng, ZHENG Zongkun, ZHANG Yi, LI Wenyin, ZHAO Fengjuan, XIAO Chengui, BAI Runye, LIN Wei. Determination of perfluoroalkyl acids in lamb liver by high performance liquid chromatography-tandem mass spectrometry combined with dispersive solid phase extraction[J]. Chinese Journal of Chromatography, ;2015, 33(5): 494-500. doi: 10.3724/SP.J.1123.2014.12034 shu

Determination of perfluoroalkyl acids in lamb liver by high performance liquid chromatography-tandem mass spectrometry combined with dispersive solid phase extraction

ZHU Pingping ^1,2 ,
YUE Zhenfeng ^1,, ,
ZHENG Zongkun ² ,
ZHANG Yi ¹ ,
LI Wenyin ^1,2 ,
ZHAO Fengjuan ¹ ,
XIAO Chengui ¹ ,
BAI Runye ^1,2 ,
LIN Wei ^1,2

1.
1. Food Inspection and Quarantine Center, Shenzhen Entry-Exit Inspection and Quarantine Bureau; Shenzhen Key Laboratory of Detection Technology R. & D. on Food Safety, Shenzhen 518045, China;

Corresponding author: YUE Zhenfeng,
Received Date: 25 December 2014
Available Online: 18 March 2015
Fund Project: 国家科技基础性工作专项重点项目(2013FY113100) (2013FY113100)科技部"十二五"科技支撑计划项目(2012BAD33B02). (2012BAD33B02)

A method was developed for the determination of 19 perfluoroalkyl acids (PFAs) in lamb liver by high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) combined with dispersive solid phase extraction. The sample was extracted with acidified acetonitrile, and then cleaned-up by a mixture of N-propylethylenediamine (PSA), C18 and graphitized carbon black (GCB) sorbents. The 19 PFAs were analyzed by HPLC-MS/MS with a C18 chromatographic column, adopting the multiple reaction monitoring (MRM) mode with negative electrospray ionization. The effects of the dosages of hydrochloric acid and the sorbents on the recoveries of the 19 PFAs were studied. For accurate quantitative analysis, the isotope internal standard method was used. The calibration curves were linear with the correlation coefficients over 0.998 in the range of 0.05-20 μg/kg for the 19 PFAs. The limits of detection were 0.004-0.111 μg/kg. The limits of quantification were 0.012-0.370 μg/kg. The mean recoveries of the 19 PFAs at spiked levels of 0.5, 1.0, 2.0 μg/kg were in the range from 80% to 128% with the relative standard deviations of 0.31%-11.1%. The developed method is rapid, simple, accurate. It is suitable for the determination of the 19 PFAs in large quantities of lamb liver samples.
1. [1]
  [1] Kissa E. Fluorinated Surfactants and Repellants. New York: Marcel Dekker Inc, 2001
2. [2]
  [2] Sedlak M D, Greig D J. J Environ Monit, 2012, 14(1): 146
3. [3]
  [3] Loi E I H, Yeung L W Y, Taniyasu S, et al. Environ Sci Technol, 2011, 45(13): 5506
4. [4]
  [4] Plumlee M H, Larabee J, Reinhard M. Chemosphere, 2008, 72(10): 1541
5. [5]
  [5] So M K, Taniyasu S, Lam P K S, et al. Arch Environ Contam Toxicol, 2006, 50: 240
6. [6]
  [6] Shen B Z, Cao W J, Zhong J. Chemistry & Bioengineering (沈葆真, 曹文军, 钟键. 化学与生物工程), 2014, 31(1): 6
7. [7]
  [7] Kato K, Wong L Y, Jia L T, et al. Environ Sci Technol, 2011, 45(19): 8037
8. [8]
  [8] Zhang T, Sun H W, Wu Q, et al. Environ Sci Technol, 2010, 44(9): 3572
9. [9]
  [9] Zhang T, Sun H W, Lin Y, et al. J Agric Food Chem, 2011, 59(20): 11168
10. [10]
  [10] Hu G C, Zheng H, Zhang L J, et al. China Environmental Science (胡国成, 郑海, 张丽娟, 等. 中国环境科学), 2013, 33(S1): 37
11. [11]
  [11] Halldorsson T I, Fei C, Olsen J, et al. Environ Sci Technol, 2008, 42(23): 8971
12. [12]
  [12] Law R J, Bersuder P, Mead L K, et al. Marine Poll Bull, 2008, 56: 792
13. [13]
  [13] Luque N, Leeuwen S V, Rubio S, et al. J Chromatogr A, 2010, 1217: 3774
14. [14]
  [14] Zhang T, Sun H W, Wu Q, et al. Environ Sci Technol, 2010, 44(9): 3572
15. [15]
  [15] Wang J M, Wang L, Feng Y J, et al. Food Science (王杰明, 王丽, 冯玉静, 等. 食品科学), 2010, 31(4): 127
16. [16]
  [16] Li W Y, Yue Z F, Zheng Z K, et al. Journal of Food Safety and Quality (黎文茵, 岳振峰, 郑宗坤, 等. 食品安全质量检测学报), 2014, 5(1): 210
17. [17]
  [17] Guo M M, Wu H Y, Li Z X, et al. Chinese Journal of Analytical Chemistry (郭萌萌, 吴海燕, 李兆新, 等. 分析化学), 2013, 41(9): 1322
18. [18]
  [18] Pan Y Y, Shi Y L, Cai Y Q. Chinese Journal of Analytical Chemistry (潘媛媛, 史亚利, 蔡亚岐. 分析化学), 2008, 36(10): 1321
19. [19]
  [19] Urairat K, Kunaporn S, Natchanun L. Anal Chim Acta, 2008, 626: 10
20. [20]
  [20] Wang L Z, Zhou Y, Huang X Y, et al. Chinese Journal of Chromatography (王连珠, 周昱, 黄小燕, 等. 色谱), 2013, 31(12): 1167
21. [21]
  [21] Liu Y, Tang Y F, Song J F, et al. Chinese Journal of Chromatography (刘永, 唐英斐, 宋金凤, 等. 色谱), 2014, 32(2): 139
22. [22]
  [22] Sun Y M, Liu Y J, Zhao J, et al. Meat Research (孙亚米, 刘勇军, 赵建, 等. 肉类研究), 2014, 28(4): 14
23. [23]
  [23] Li J, Zhang H, Chai Z F, et al. Journal of Instrumental Analysis (李静, 张鸿, 柴之芳, 等. 分析测试学报), 2014, 33(10): 1109
24. [24]
  [24] Lehotay S J, Son K A, Kwon H, et al. J Chromatogr A, 2010, 1217: 2548
25. [25]
  [25] Liu L Z, Guo X D, Fang J, et al. Journal of Instrumental Analysis (刘莉治, 郭新东, 方军, 等. 分析测试学报), 2013, 32(7): 862
1. [1]
  Yanhui Zhong , Ran Wang , Zian Lin . Analysis of Halogenated Quinone Compounds in Environmental Water by Dispersive Solid-Phase Extraction with Liquid Chromatography-Triple Quadrupole Mass Spectrometry. University Chemistry, 2024, 39(11): 296-303. doi: 10.12461/PKU.DXHX202402017
2. [2]
  Zunxiang Zeng , Yuling Hu , Yufei Hu , Hua Xiao . Analysis of Plant Essential Oils by Supercritical CO₂Extraction with Gas Chromatography-Mass Spectrometry: An Instrumental Analysis Comprehensive Experiment Teaching Reform. University Chemistry, 2024, 39(3): 274-282. doi: 10.3866/PKU.DXHX202309069
3. [3]
  Mingyang Men , Jinghua Wu , Gaozhan Liu , Jing Zhang , Nini Zhang , Xiayin Yao . 液相法制备硫化物固体电解质及其在全固态锂电池中的应用. Acta Physico-Chimica Sinica, 2025, 41(1): 2309019-. doi: 10.3866/PKU.WHXB202309019
4. [4]
  Chongjing Liu , Yujian Xia , Pengjun Zhang , Shiqiang Wei , Dengfeng Cao , Beibei Sheng , Yongheng Chu , Shuangming Chen , Li Song , Xiaosong Liu . Understanding Solid-Gas and Solid-Liquid Interfaces through Near Ambient Pressure X-Ray Photoelectron Spectroscopy. Acta Physico-Chimica Sinica, 2025, 41(2): 100013-. doi: 10.3866/PKU.WHXB202309036
5. [5]
  Gaoyan Chen , Chaoyue Wang , Juanjuan Gao , Junke Wang , Yingxiao Zong , Kin Shing Chan . Heart to Heart: Exploring Cardiac CT. University Chemistry, 2024, 39(9): 146-150. doi: 10.12461/PKU.DXHX202402011
6. [6]
  Xiaowu Zhang , Pai Liu , Qishen Huang , Shufeng Pang , Zhiming Gao , Yunhong Zhang . Acid-Base Dissociation Equilibrium in Multiphase System: Effect of Gas. University Chemistry, 2024, 39(4): 387-394. doi: 10.3866/PKU.DXHX202310021
7. [7]
  Chunai Dai , Yongsheng Han , Luting Yan , Zhen Li , Yingze Cao . Ideological and Political Design of Solid-liquid Contact Angle Measurement Experiment. University Chemistry, 2024, 39(2): 28-33. doi: 10.3866/PKU.DXHX202306065
8. [8]
  Jiao CHEN , Yi LI , Yi XIE , Dandan DIAO , Qiang XIAO . Vapor-phase transport of MFI nanosheets for the fabrication of ultrathin b-axis oriented zeolite membranes. Chinese Journal of Inorganic Chemistry, 2024, 40(3): 507-514. doi: 10.11862/CJIC.20230403
9. [9]
  Zhiwen HU , Weixia DONG , Qifu BAO , Ping LI . Low-temperature synthesis of tetragonal BaTiO₃ for piezocatalysis. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 857-866. doi: 10.11862/CJIC.20230462
10. [10]
  Haiyang Zhang , Yanzhao Dong , Haojie Li , Ruili Guo , Zhicheng Zhang , Jiangjiexing Wu . Exploring the Integration of Chemical Engineering Principle Experiment with Cutting-Edge Research Achievements. University Chemistry, 2024, 39(10): 308-313. doi: 10.12461/PKU.DXHX202405035
11. [11]
  Yang Chen , Peng Chen , Yuyang Song , Yuxue Jin , Song Wu . Application of Chemical Transformation Driven Impurity Separation in Experiments Teaching: A Novel Method for Purification of α-Fluorinated Mandelic Acid. University Chemistry, 2024, 39(6): 253-263. doi: 10.3866/PKU.DXHX202310077
12. [12]
  Jiahe LIU , Gan TANG , Kai CHEN , Mingda ZHANG . Effect of low-temperature electrolyte additives on low-temperature performance of lithium cobaltate batteries. Chinese Journal of Inorganic Chemistry, 2025, 41(4): 719-728. doi: 10.11862/CJIC.20250023
13. [13]
  Ran Yu , Chen Hu , Ruili Guo , Ruonan Liu , Lixing Xia , Cenyu Yang , Jianglan Shui . 杂多酸H₃PW₁₂O₄₀高效催化MgH₂储氢. Acta Physico-Chimica Sinica, 2025, 41(1): 2308032-. doi: 10.3866/PKU.WHXB202308032
14. [14]
  Shiyan Cheng , Yonghong Ruan , Lei Gong , Yumei Lin . Research Advances in Friedel-Crafts Alkylation Reaction. University Chemistry, 2024, 39(10): 408-415. doi: 10.12461/PKU.DXHX202403024
15. [15]
  Lihui Jiang , Wanrong Dong , Hua Yang , Yongqing Xia , Hongjian Peng , Jun Yuan , Xiaoqian Hu , Zihan Zeng , Yingping Zou , Yiming Luo . Study on Extraction of p-Hydroxyacetophenone. University Chemistry, 2024, 39(11): 259-268. doi: 10.12461/PKU.DXHX202402056
16. [16]
  Zian Lin , Yingxue Jin . Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI-MS) for Disease Marker Screening and Identification: A Comprehensive Experiment Teaching Reform in Instrumental Analysis. University Chemistry, 2024, 39(11): 327-334. doi: 10.12461/PKU.DXHX202403066
17. [17]
  Peng XU , Shasha WANG , Nannan CHEN , Ao WANG , Dongmei YU . Preparation of three-layer magnetic composite Fe₃O₄@polyacrylic acid@ZiF-8 for efficient removal of malachite green in water. Chinese Journal of Inorganic Chemistry, 2024, 40(3): 544-554. doi: 10.11862/CJIC.20230239
18. [18]
  Fang Niu , Rong Li , Qiaolan Zhang . Analysis of Gas-Solid Adsorption Behavior in Resistive Gas Sensing Process. University Chemistry, 2024, 39(8): 142-148. doi: 10.3866/PKU.DXHX202311102
19. [19]
  Yanan Liu , Yufei He , Dianqing Li . Preparation of Highly Dispersed LDHs-based Catalysts and Testing of Nitro Compound Reduction Performance: A Comprehensive Chemical Experiment for Research Transformation. University Chemistry, 2024, 39(8): 306-313. doi: 10.3866/PKU.DXHX202401081
20. [20]
  Xiaoning TANG , Shu XIA , Jie LEI , Xingfu YANG , Qiuyang LUO , Junnan LIU , An XUE . Fluorine-doped MnO₂ with oxygen vacancy for stabilizing Zn-ion batteries. Chinese Journal of Inorganic Chemistry, 2024, 40(9): 1671-1678. doi: 10.11862/CJIC.20240149

Get Citation

PDF

XML

Metrics

PDF Downloads(0)
Abstract views(181)
HTML views(10)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142