Citation: YANG Huamei, HANG Li. Determination of four frequently-used essences in foods by ultra performance liquid chromatography-tandem mass spectrometry[J]. Chinese Journal of Chromatography, ;2015, 33(3): 250-255. doi: 10.3724/SP.J.1123.2014.11018 shu

Determination of four frequently-used essences in foods by ultra performance liquid chromatography-tandem mass spectrometry

YANG Huamei ^, ,
HANG Li

1.
Taizhou Center for Disease Control and Prevention, Taizhou 225300, China

Corresponding author: YANG Huamei,
Received Date: 13 November 2014
Available Online: 6 January 2015

A method has been developed for the simultaneous determination of vanillin, ethyl vanillin, maltol and ethyl maltol in foods by ultra performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (UPLC-ESI-MS/MS). The sample was extracted with ultrapure water, and purified with SPE column. The target compounds were separated on a C18 column with the gradient elution of methanol and water containing 0.002 mol/L ammonium acetate and 0.1%(v/v) formic acid. The four components were determined in the modes of electrospray positive ionization (ESI⁺) and multiple reaction monitoring (MRM). The linear ranges were 10-1000 μg/L for vanillin and maltol and 5-500 μg/L for ethyl vanillin and ethyl maltol, with the correlation coefficients more than 0.999. The recoveries of the four compounds ranged from 75.8% to 116%, with the relative standard deviations (RSDs) of 1.58%-4.01%. The method showed good extraction efficiency, high sensitivity and good reproducibility. It is suitable for the simultaneous detection of vanillin, ethyl vanillin, maltol and ethyl maltol in foods.
- ultra performance liquid chromatography-electrospray ionization tandem mass spectrometry (UPLC-ESI-MS/MS),
- vanillin,
- ethyl vanillin,
- maltol,
- ethyl vanillin,
- food
1. [1]
  [1] Liu S T, Liu Y H, Ruan R S, et al. Science and Technology of Food Industry (刘士涛, 刘玉环, 阮榕生, 等. 食品工业科技), 2012(9): 426
2. [2]
  [2] Chen J M. Food Research and Development (陈金明. 食品研究与开发), 2004, 25(1): 34
3. [3]
  [3] Pan L. Journal of Hunan City University: Natural Science (潘磊. 湖南城市学院学报: 自然科学版), 2011, 20(2): 48
4. [4]
  [4] Hironishi M, Kordek R, Yanagihara R, et al. Neurodegeneration, 1996, 5(4): 325
5. [5]
  [5] Liang R F, Niu Q. Journal of Toxicology (梁瑞峰, 牛侨. 毒理学杂志), 2011, 25(6): 467
6. [6]
  [6] Liang R F, Li W Q, Niu Q. Journal of Environment and Health (梁瑞峰, 李伟庆, 牛侨. 环境与健康杂志), 2011, 28 (4): 302
7. [7]
  [7] Zhang G W, Ni Y N. Journal of Analytical Science (张国文, 倪永年. 分析科学学报), 2005, 21(1): 20
8. [8]
  [8] Ni Y N, Wang P P. Journal of Nanchang University: Natural Science (倪永年, 王苹苹. 南昌大学学报: 理科版), 2012, 36(1): 43
9. [9]
  [9] Zhou J, Di J W, Wu Y, et al. Chinese Journal of Applied Chemistry (周君, 狄俊伟, 吴莹, 等. 应用化学), 2008, 25(1): 81
10. [10]
  [10] Peng S H, Ma W H, Di J W. Chinese Journal of Spectroscopy Laboratory (彭少华, 马文华, 狄俊伟. 光谱实验室), 2005, 22(4): 680
11. [11]
  [11] Wang H, Liu Y Q, Yang H M, et al. Food Science and Technology (王浩, 刘艳琴, 杨红梅, 等. 食品科技), 2006(8): 235
12. [12]
  [12] Jing L J, Han W, Yan G L. Food Science (景丽洁, 韩伟, 闫光烈. 食品科学), 2006, 27(4): 205
13. [13]
  [13] Farthing D, Sica D, Abernathy C, et al. J Chromatogr B, 1999, 726: 303
14. [14]
  [14] Waliszewski K N, Pardio V T, Ovando S L. Food Chem, 2006, 101: 1059
15. [15]
  [15] Li H F, Yang H Y, Zhang Y, et al. Chinese Journal of Chromatography (李海芳, 杨红云, 张英, 等. 色谱), 2014, 32(4): 413
16. [16]
  [16] Sanfeliu Alonso M C, Lahuerta Zamora L, Martinez Calatayud J. Anal Chim Acta, 2001, 438: 157
17. [17]
  [17] de Jager L S, Perfetti G A, Diachenko G W. Food Chem, 2008, 107: 1701
18. [18]
  [18] Li X Y, Wang H. Farm Machinery (李小运, 王浩. 农业机械), 2012(3): 126
19. [19]
  [19] de Jager L S, Perfetti G A, Diachenko G W. J Chromatogr A, 2007, 1145: 83
20. [20]
  [20] Ohashi M, Omae H, Hashida M. J Chromatogr A, 2007, 1138: 262
21. [21]
  [21] Ren H B, Bie Z Y, Wei Y P, et al. Chinese Journal of Analysis Laboratory (任呼博, 别振英, 蔚亦沛, 等. 分析试验室), 2014, 33(8): 950
22. [22]
  [22] Ni Y N, Zhang G W, Serge K. Food Chem, 2005, 89(3): 465
1. [1]
  Zhilian Liu , Wengui Wang , Hongxiao Yang , Yu Cui , Shoufeng Wang . Ideological and Political Education Design for the Synthesis of Irinotecan Drug Intermediate 7-Ethyl Camptothecin. University Chemistry, 2024, 39(2): 89-93. doi: 10.3866/PKU.DXHX202306012
2. [2]
  Yongqing Kuang , Jie Liu , Jianjun Feng , Wen Yang , Shuanglian Cai , Ling Shi . Experimental Design for the Two-Step Synthesis of Paracetamol from 4-Hydroxyacetophenone. University Chemistry, 2024, 39(8): 331-337. doi: 10.12461/PKU.DXHX202403012
3. [3]
  Lu XU , Chengyu ZHANG , Wenjuan JI , Haiying YANG , Yunlong FU . Zinc metal-organic framework with high-density free carboxyl oxygen functionalized pore walls for targeted electrochemical sensing of paracetamol. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 907-918. doi: 10.11862/CJIC.20230431
4. [4]
  Yanhui Zhong , Ran Wang , Zian Lin . Analysis of Halogenated Quinone Compounds in Environmental Water by Dispersive Solid-Phase Extraction with Liquid Chromatography-Triple Quadrupole Mass Spectrometry. University Chemistry, 2024, 39(11): 296-303. doi: 10.12461/PKU.DXHX202402017
5. [5]
  Simin Fang , Hong Wu , Sizhe Sheng , Lingling Li , Yuxi Wang , Hongchun Li , Jun Jiang . The Food Kingdom Lecture Series: The Science behind Color. University Chemistry, 2024, 39(9): 177-182. doi: 10.12461/PKU.DXHX202402012
6. [6]
  Shengbiao Zheng , Liang Li , Nini Zhang , Ruimin Bao , Ruizhang Hu , Jing Tang . Metal-Organic Framework-Derived Materials Modified Electrode for Electrochemical Sensing of Tert-Butylhydroquinone: A Recommended Comprehensive Chemistry Experiment for Translating Research Results. University Chemistry, 2024, 39(7): 345-353. doi: 10.3866/PKU.DXHX202310096
7. [7]
  Zunxiang Zeng , Yuling Hu , Yufei Hu , Hua Xiao . Analysis of Plant Essential Oils by Supercritical CO₂Extraction with Gas Chromatography-Mass Spectrometry: An Instrumental Analysis Comprehensive Experiment Teaching Reform. University Chemistry, 2024, 39(3): 274-282. doi: 10.3866/PKU.DXHX202309069
8. [8]
  Mingyang Men , Jinghua Wu , Gaozhan Liu , Jing Zhang , Nini Zhang , Xiayin Yao . 液相法制备硫化物固体电解质及其在全固态锂电池中的应用. Acta Physico-Chimica Sinica, 2025, 41(1): 2309019-. doi: 10.3866/PKU.WHXB202309019
9. [9]
  Yutong Dong , Huiling Xu , Yucheng Zhao , Zexin Zhang , Ying Wang . The Hidden World of Surface Tension and Droplets. University Chemistry, 2024, 39(6): 357-365. doi: 10.3866/PKU.DXHX202312022
10. [10]
  Gaoyan Chen , Chaoyue Wang , Juanjuan Gao , Junke Wang , Yingxiao Zong , Kin Shing Chan . Heart to Heart: Exploring Cardiac CT. University Chemistry, 2024, 39(9): 146-150. doi: 10.12461/PKU.DXHX202402011
11. [11]
  Zhaomei LIU , Wenshi ZHONG , Jiaxin LI , Gengshen HU . Preparation of nitrogen-doped porous carbons with ultra-high surface areas for high-performance supercapacitors. Chinese Journal of Inorganic Chemistry, 2024, 40(4): 677-685. doi: 10.11862/CJIC.20230404
12. [12]
  Xiaowu Zhang , Pai Liu , Qishen Huang , Shufeng Pang , Zhiming Gao , Yunhong Zhang . Acid-Base Dissociation Equilibrium in Multiphase System: Effect of Gas. University Chemistry, 2024, 39(4): 387-394. doi: 10.3866/PKU.DXHX202310021
13. [13]
  Renxiao Liang , Zhe Zhong , Zhangling Jin , Lijuan Shi , Yixia Jia . A Palladium/Chiral Phosphoric Acid Relay Catalysis for the One-Pot Three-Step Synthesis of Chiral Tetrahydroquinoline. University Chemistry, 2024, 39(5): 209-217. doi: 10.3866/PKU.DXHX202311024
14. [14]
  Jingming Li , Bowen Ding , Nan Li , Nurgul . Application of Comparative Teaching Method in Experimental Project Design of Instrumental Analysis Course: A Case Study in Chromatography Experiment Teaching. University Chemistry, 2024, 39(8): 263-269. doi: 10.3866/PKU.DXHX202312078
15. [15]
  Jiao CHEN , Yi LI , Yi XIE , Dandan DIAO , Qiang XIAO . Vapor-phase transport of MFI nanosheets for the fabrication of ultrathin b-axis oriented zeolite membranes. Chinese Journal of Inorganic Chemistry, 2024, 40(3): 507-514. doi: 10.11862/CJIC.20230403
16. [16]
  Zhiwen HU , Weixia DONG , Qifu BAO , Ping LI . Low-temperature synthesis of tetragonal BaTiO₃ for piezocatalysis. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 857-866. doi: 10.11862/CJIC.20230462
17. [17]
  Chunai Dai , Yongsheng Han , Luting Yan , Zhen Li , Yingze Cao . Ideological and Political Design of Solid-liquid Contact Angle Measurement Experiment. University Chemistry, 2024, 39(2): 28-33. doi: 10.3866/PKU.DXHX202306065
18. [18]
  Feiya Cao , Qixin Wang , Pu Li , Zhirong Xing , Ziyu Song , Heng Zhang , Zhibin Zhou , Wenfang Feng . Magnesium-Ion Conducting Electrolyte Based on Grignard Reaction: Synthesis and Properties. University Chemistry, 2024, 39(3): 359-368. doi: 10.3866/PKU.DXHX202308094
19. [19]
  Haiyang Zhang , Yanzhao Dong , Haojie Li , Ruili Guo , Zhicheng Zhang , Jiangjiexing Wu . Exploring the Integration of Chemical Engineering Principle Experiment with Cutting-Edge Research Achievements. University Chemistry, 2024, 39(10): 308-313. doi: 10.12461/PKU.DXHX202405035
20. [20]
  Zian Lin , Yingxue Jin . Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI-MS) for Disease Marker Screening and Identification: A Comprehensive Experiment Teaching Reform in Instrumental Analysis. University Chemistry, 2024, 39(11): 327-334. doi: 10.12461/PKU.DXHX202403066

Get Citation

PDF

XML

Metrics

PDF Downloads(0)
Abstract views(203)
HTML views(6)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142