Citation: ZHANG Qianchun, XIAO Xiaohua, LI Gongke. Advances on sample pretreatment and analytical method for the analysis of heterocyclic amines in meat products[J]. Chinese Journal of Chromatography, ;2014, 32(9): 975-980. doi: 10.3724/SP.J.1123.2014.05011 shu

Advances on sample pretreatment and analytical method for the analysis of heterocyclic amines in meat products

1.
1. School of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou 510275, China;

Corresponding author: XIAO Xiaohua, LI Gongke,
Received Date: 15 May 2014
Available Online: 1 July 2014
Fund Project: 国家自然科学基金项目(21127008) (21127008)高等学校博士学科点专项基金项目(20120171110001) (20120171110001)广东省自然科学基金项目(S2012010010787). (S2012010010787)

Heterocyclic amines (HAs) are considered as highly potential mutagens and carcinogens in cooked meat products. Efficient sample pretreatment as well as sensitive analytical method is very important for the determination of HAs in complex samples. In this paper, some sample pretreatment methods such as solvent extraction, solid-phase extraction, and solid-phase microextraction as well as analytical methods including liquid chromatography, and liquid chromatography-mass spectrometry are reviewed; The progress of HAs analysis is also prospected. A total of 51 references are cited.
- sample pretreatment,
- analytical method,
- heterocyclic amines,
- meat products,
- review
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