Citation: CHENG Zhi, ZHANG Rong, LIU Weihua, WANG Jinhua, WANG Minglin. Rapid screening and quantitative analysis of 144 pesticide residues in traditional Chinese medicinal herbs by gas chromatography-tandem mass spectrometry[J]. Chinese Journal of Chromatography, ;2014, 32(1): 57-68. doi: 10.3724/SP.J.1123.2013.09043 shu

Rapid screening and quantitative analysis of 144 pesticide residues in traditional Chinese medicinal herbs by gas chromatography-tandem mass spectrometry

CHENG Zhi ¹ ,
ZHANG Rong ² ,
LIU Weihua ² ,
WANG Jinhua ^2,, ,
WANG Minglin ^1,,

1.
1. College of Food Science and Engineering, Shandong Agriculture University, Tai'an 271000, China;

Corresponding author: WANG Jinhua, WANG Minglin,
Received Date: 26 September 2013
Available Online: 18 November 2013
Fund Project: 国家质检总局科技计划项目(2013IK143). (2013IK143)

An analytical method for the simultaneous determination of 144 pesticide residues in traditional Chinese medicinal herbs was established based on optimized QuEChERS with gas chromatography-tandem mass spectrometry (GC-MS/MS). The influences of different extraction solvents, different buffer systems and different purifying agents on the recoveries of the pesticides were investigated. The pesticide residues in the samples were extracted with acetonitrile, then cleaned-up by mixed sorbents and analyzed by GC-MS/MS in multi-reaction monitoring (MRM) mode. The external standard method was applied to quantify the pesticides. The linear range of the method was from 20 to 2000 μg/kg with the correlation coefficients (r²) of more than 0.983. The recoveries of the pesticides at the spiked levels of 20, 50 and 200 μg/kg ranged from 74.3% to 111.8% with the relative standard deviations lower than 15%, except for acephate, amitraz and aldrin. The method was successfully used for the analysis of target pesticides in testing samples, and had a good consistency in results with the existed standard one. This multi-residue analytical method allows for a rapid, efficient, sensitive and reliable screening and quantitative analysis of the target pesticides in traditional Chinese medicinal herbs.
- QuEChERS,
- gas chromatography-tandem mass spectrometry (GC-MS/MS),
- multi-residue pesticides,
- traditional Chinese medicinal herbs
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