Citation: NIU Zengyuan, LUO Xin, YE Xiwen, WANG Huihui, LI Jingying. Determination of carcinogenic aromatic amines derived from azo colorants in plastic components of electrical and electronic products by high performance liquid chromatography-mass spectrometry[J]. Chinese Journal of Chromatography, ;2014, 32(1): 34-39. doi: 10.3724/SP.J.1123.2013.08005 shu

Determination of carcinogenic aromatic amines derived from azo colorants in plastic components of electrical and electronic products by high performance liquid chromatography-mass spectrometry

NIU Zengyuan ^1,, ,
LUO Xin ¹ ,
YE Xiwen ¹ ,
WANG Huihui ² ,
LI Jingying ²

1.
1. Technical Center for Inspection and Quarantine of Shandong Entry-Exit Inspection and Quarantine Bureau, Qingdao 266002, China;

Corresponding author: NIU Zengyuan,
Received Date: 1 August 2013
Available Online: 20 September 2013
Fund Project: 质检公益性行业科研专项(10-66) (10-66)国家质检总局科研项目计划(2011IK037) (2011IK037)国家认监委标准制修订项目(2011B265k). (2011B265k)

A study for the simultaneous determination of 21 primary aromatic amines derived from the reduction of the azo colorants in plastic components of electrical and electronic products was conducted. Organic solvents were used to dissolve or swell the plastics to release the azo dyes existing in the plastic components. The azo colorants were reduced to aromatic amines under strong reducing condition of dithionite. Aromatic amines were extracted with methyl tert-butyl ether. Methanol-water (1:1, v/v) was used to concentrate the extract to constant-volume for HPLC-MS analysis. The analytes were separated on a ZORBAX Eclipse XDB C₁₈ column using the gradient elution with acetonitrile and 0.1% (v/v) formic acid aqueous solution at a flow rate of 0.6 mL/min. The analyte confirmation was performed using retention time and characteristic ions in selected ion monitoring (SIM) mode. The correlation coefficients (r) of all the standard curves were more than 0.998, and the limits of quantification of the analytes were 0.5 mg/kg. The recoveries were 60.1%-129.5% for the 21 aromatic amines with the RSDs not more than 14.0% except for a few compounds. The results showed that the banned azo colorants in the plastic products can be analyzed qualitatively and quantitatively through reductive conversion into aromatic amines. In addition, this method has high accuracy and good precision.
- high performance liquid chromatography-mass spectrometry (HPLC-MS),
- azo colorants,
- aromatic amines,
- plastic,
- electrical and electronic products
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