Citation: DING Liping, GUO Jing, CHEN Zhitao, ZHAO Jianhui, ZHENG Ling, CAI Wei. Determination of musk ketone in aquatic products by gas chromatography-mass spectrometry with dispersive solid phase extraction[J]. Chinese Journal of Chromatography, ;2013, 31(5): 485-489. doi: 10.3724/SP.J.1123.2012.11017 shu

Determination of musk ketone in aquatic products by gas chromatography-mass spectrometry with dispersive solid phase extraction

1.
Technology Center of Fuqing Entry-Exit Inspection and Quarantine Bureau, Fuqing 350300, China

Corresponding author: DING Liping,
Received Date: 26 November 2012
Available Online: 14 January 2013
Fund Project: 福建出入境检验检疫局科技项目(FK2012-16). (FK2012-16)

A dispersive solid phase extraction coupled with gas chromatography-mass spectrometry (GC-MS) method was established for the determination of trace amounts of musk ketone in aquatic products. The target analyte in the samples was extracted with acetonitrile containing 1% acetic acid, cleaned-up with the mixture of N-propyl-ethylenediamine (PSA), C₁₈ and graphitized carbon (GCB), and analyzed by GC-MS under selected ion monitoring (SIM) mode and quantified by the external standard method. The orthogonal experiment was carried out to optimize the pre-treatment conditions. Under the optimal conditions, good linear relationship was obtained in the range of 1-50 μg/L for musk ketone with correlation coefficient not less than 0.999, and the limits of detection (S/N=3) was 0.30 μg/kg. The recoveries of musk ketone in the prawn and tilapia blank samples at three spiked levels of 1.0, 2.0 and 10.0 μg/kg ranged from 91.8% to 110.6% with RSDs in the range of 2.6%-8.4%. The method is simple, rapid and accurate, and can be used for the routine analysis of musk ketone in aquatic products.
- gas chromatography-mass spectrometry (GC-MS),
- dispersive solid phase extraction,
- musk ketone,
- aquatic products
1. [1]
  [1] Hu H Y, Wang C, Guo M T. Ecology and Environment (胡洪营, 王超, 郭美婷. 生态环境), 2005, 14(6): 947
2. [2]
  [2] Ma Y M, Qu Z H, Liu K M, et al. Asian Journal of Ecotoxicology (马永民, 渠志华, 刘克明, 等. 生态毒理学报), 2006, 1(3): 278
3. [3]
  [3] Chen D H, Zeng X Y, Sheng Y Q, et al. Environmental Monitoring in China (陈多宏, 曾祥英, 盛彦清, 等. 中国环境监测), 2008, 24(1): 67
4. [4]
  [4] Zhou Q X, Wang M E, Fan F, et al. Acta Scientiae Circumstantiae (周启星, 王美娥, 范飞, 等. 环境科学学报), 2008, 28(1): 1
5. [5]
  [5] Zeng X Y, Sheng G Y, Xiong Y, et al. Chemosphere, 2005, 60(6): 817
6. [6]
  [6] Yamagishi T, Miyazaki T, Horii S, et al. Bull Environm Contam Toxicol, 1981, 26(1): 656
7. [7]
  [7] Gao Y P, Wu H J. Electrical Appliances (高一盼, 伍华嘉. 日用电器), 2007(12): 5
8. [8]
  [8] Lü Y, Hu X F, Wang P H, et al. Environmental Chemistry (吕妍, 胡晓芳, 王朋华, 等. 环境化学), 2008, 27(3): 382
9. [9]
  [9] Liang G F, Wang J, Zhou J, et al. Enviromental Chemistry (梁高锋, 王珺, 周静, 等. 环境化学), 2010, 29(1): 113
10. [10]
  [10] Hu Z J, Shi Y L, Cai Y Q. Environmental Chemistry (胡正君, 史亚利, 蔡亚岐. 环境化学), 2010, 29(3): 530
11. [11]
  [11] Che J S, Wang L P, Song Q J, et al. Environmental Chemistry (车金水, 王利平, 宋启军, 等. 环境化学), 2011, 30(6): 1197
12. [12]
  [12] Yu R P, Che J S, He E Q, et al. Chinese Journal of Analytical Chemistry (虞锐鹏, 车金水, 何恩奇, 等. 分析化学), 2012, 40(1): 159
13. [13]
  [13] Wei N Y, Ma C H, Duan T X. Chinese Journal of Chromatography (魏宁漪, 马长华, 段天璇. 色谱), 2005, 23(5): 565
14. [14]
  [14] Hu Z J, Shi Y L, Cai Y Q. Chinese Journal of Analytical Chemistry (胡正君, 史亚利, 蔡亚岐. 分析化学), 2010, 38(6): 885
15. [15]
  [15] Ma Q, Ba H, Wang C, et al. Chinese Journal of Analytical Chemistry (马强, 白桦, 王超, 等. 分析化学), 2009, 37(12): 1776
16. [16]
  [16] Zeng X Y, Chen D H, Gui H Y, et al. Administration and Technique of Environmental Monitoring (曾祥英, 陈多宏, 桂红艳, 等. 环境监测管理与技术), 2006, 18(3): 7
17. [17]
  [17] Anastassiades M, Lehotay S J, Stajnbaher D, et al. J AOAC Int, 2003, 86(2): 412
18. [18]
  [18] Bester K. J Chromatogr A, 2009, 1216: 470
19. [19]
  [19] Rudel H, Bohmer W, Schroter-Kermani C. J Environ Monit, 2006, 8: 812
20. [20]
  [20] Ding L P, Wei Y H. Agrochemicals (丁立平, 魏云昊. 农药), 2011, 50(5): 352
21. [21]
  [21] Xu P J, Gao X S, Tao B, et al. Chinese Journal of Analytical Chemistry (许鹏军, 高晓莎, 陶晡, 等. 分析化学), 2008, 36(11): 1515
1. [1]
  Yanhui Zhong , Ran Wang , Zian Lin . Analysis of Halogenated Quinone Compounds in Environmental Water by Dispersive Solid-Phase Extraction with Liquid Chromatography-Triple Quadrupole Mass Spectrometry. University Chemistry, 2024, 39(11): 296-303. doi: 10.12461/PKU.DXHX202402017
2. [2]
  Zunxiang Zeng , Yuling Hu , Yufei Hu , Hua Xiao . Analysis of Plant Essential Oils by Supercritical CO₂Extraction with Gas Chromatography-Mass Spectrometry: An Instrumental Analysis Comprehensive Experiment Teaching Reform. University Chemistry, 2024, 39(3): 274-282. doi: 10.3866/PKU.DXHX202309069
3. [3]
  Xiaowu Zhang , Pai Liu , Qishen Huang , Shufeng Pang , Zhiming Gao , Yunhong Zhang . Acid-Base Dissociation Equilibrium in Multiphase System: Effect of Gas. University Chemistry, 2024, 39(4): 387-394. doi: 10.3866/PKU.DXHX202310021
4. [4]
  Jiao CHEN , Yi LI , Yi XIE , Dandan DIAO , Qiang XIAO . Vapor-phase transport of MFI nanosheets for the fabrication of ultrathin b-axis oriented zeolite membranes. Chinese Journal of Inorganic Chemistry, 2024, 40(3): 507-514. doi: 10.11862/CJIC.20230403
5. [5]
  Lihui Jiang , Wanrong Dong , Hua Yang , Yongqing Xia , Hongjian Peng , Jun Yuan , Xiaoqian Hu , Zihan Zeng , Yingping Zou , Yiming Luo . Study on Extraction of p-Hydroxyacetophenone. University Chemistry, 2024, 39(11): 259-268. doi: 10.12461/PKU.DXHX202402056
6. [6]
  Gaoyan Chen , Chaoyue Wang , Juanjuan Gao , Junke Wang , Yingxiao Zong , Kin Shing Chan . Heart to Heart: Exploring Cardiac CT. University Chemistry, 2024, 39(9): 146-150. doi: 10.12461/PKU.DXHX202402011
7. [7]
  Chongjing Liu , Yujian Xia , Pengjun Zhang , Shiqiang Wei , Dengfeng Cao , Beibei Sheng , Yongheng Chu , Shuangming Chen , Li Song , Xiaosong Liu . Understanding Solid-Gas and Solid-Liquid Interfaces through Near Ambient Pressure X-Ray Photoelectron Spectroscopy. Acta Physico-Chimica Sinica, 2025, 41(2): 100013-. doi: 10.3866/PKU.WHXB202309036
8. [8]
  Fang Niu , Rong Li , Qiaolan Zhang . Analysis of Gas-Solid Adsorption Behavior in Resistive Gas Sensing Process. University Chemistry, 2024, 39(8): 142-148. doi: 10.3866/PKU.DXHX202311102
9. [9]
  Zhiwen HU , Weixia DONG , Qifu BAO , Ping LI . Low-temperature synthesis of tetragonal BaTiO₃ for piezocatalysis. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 857-866. doi: 10.11862/CJIC.20230462
10. [10]
  Haiyang Zhang , Yanzhao Dong , Haojie Li , Ruili Guo , Zhicheng Zhang , Jiangjiexing Wu . Exploring the Integration of Chemical Engineering Principle Experiment with Cutting-Edge Research Achievements. University Chemistry, 2024, 39(10): 308-313. doi: 10.12461/PKU.DXHX202405035
11. [11]
  Mingyang Men , Jinghua Wu , Gaozhan Liu , Jing Zhang , Nini Zhang , Xiayin Yao . 液相法制备硫化物固体电解质及其在全固态锂电池中的应用. Acta Physico-Chimica Sinica, 2025, 41(1): 2309019-. doi: 10.3866/PKU.WHXB202309019
12. [12]
  Yue Zhao , Yanfei Li , Tao Xiong . Copper Hydride-Catalyzed Nucleophilic Additions of Unsaturated Hydrocarbons to Aldehydes and Ketones. University Chemistry, 2024, 39(4): 280-285. doi: 10.3866/PKU.DXHX202309001
13. [13]
  Liangzhen Hu , Li Ni , Ziyi Liu , Xiaohui Zhang , Bo Qin , Yan Xiong . A Green Chemistry Experiment on Electrochemical Synthesis of Benzophenone. University Chemistry, 2024, 39(6): 350-356. doi: 10.3866/PKU.DXHX202312001
14. [14]
  Guojie Xu , Fang Yu , Yunxia Wang , Meng Sun . Introduction to Metal-Catalyzed β-Carbon Elimination Reaction of Cyclopropenones. University Chemistry, 2024, 39(8): 169-173. doi: 10.3866/PKU.DXHX202401060
15. [15]
  Yongqing Kuang , Jie Liu , Jianjun Feng , Wen Yang , Shuanglian Cai , Ling Shi . Experimental Design for the Two-Step Synthesis of Paracetamol from 4-Hydroxyacetophenone. University Chemistry, 2024, 39(8): 331-337. doi: 10.12461/PKU.DXHX202403012
16. [16]
  Shuang Yang , Qun Wang , Caiqin Miao , Ziqi Geng , Xinran Li , Yang Li , Xiaohong Wu . Ideological and Political Education Design for Research-Oriented Experimental Course of Highly Efficient Hydrogen Production from Water Electrolysis in Aerospace Perspective. University Chemistry, 2024, 39(11): 269-277. doi: 10.12461/PKU.DXHX202403044
17. [17]
  Yurong Tang , Yunren Shi , Yi Xu , Bo Qin , Yanqin Xu , Yunfei Cai . Innovative Experiment and Course Transformation Practice of Visible-Light-Mediated Photocatalytic Synthesis of Isoquinolinone. University Chemistry, 2024, 39(5): 296-306. doi: 10.3866/PKU.DXHX202311087
18. [18]
  Zhuoming Liang , Ming Chen , Zhiwen Zheng , Kai Chen . Multidimensional Studies on Ketone-Enol Tautomerism of 1,3-Diketones By ¹H NMR. University Chemistry, 2024, 39(7): 361-367. doi: 10.3866/PKU.DXHX202311029
19. [19]
  Qin Hu , Liuyun Chen , Xinling Xie , Zuzeng Qin , Hongbing Ji , Tongming Su . Ni掺杂构建电子桥及激活MoS₂惰性基面增强光催化分解水产氢. Acta Physico-Chimica Sinica, 2024, 40(11): 2406024-. doi: 10.3866/PKU.WHXB202406024
20. [20]
  Chunai Dai , Yongsheng Han , Luting Yan , Zhen Li , Yingze Cao . Ideological and Political Design of Solid-liquid Contact Angle Measurement Experiment. University Chemistry, 2024, 39(2): 28-33. doi: 10.3866/PKU.DXHX202306065

Get Citation

PDF

XML

Metrics

PDF Downloads(0)
Abstract views(198)
HTML views(23)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142