Citation: LI Ying, WU Ya-Feng, YUAN Liang, LIU Song-Qin. Application of Atom Transfer Radical Polymerization in Biosensing[J]. Chinese Journal of Analytical Chemistry, ;2012, 40(12): 1797-1802. doi: 10.3724/SP.J.1096.2012.20531 shu

Application of Atom Transfer Radical Polymerization in Biosensing

1.
School of Chemistry and Chemical Engineering, Southeast University, Nanjing 210096, China

Corresponding author: LIU Song-Qin,
Received Date: 23 May 2012
Available Online: 26 September 2012
Fund Project: 本文系国家自然科学基金资助项目(No.20875013) (No.20875013)

Atom transfer radical polymerization (ATRP) is a new class of signal amplification method. The polymer growth results in local accumulation of monomers to form long-chain polymers. The growth of long chain polymeric materials provides excess active groups for electroactive or photoactive molecules coupling, which in turn significantly increases the loading of signal molecules and enhanced detection sensitivity. This review introduced the mechanism of ATRP, summarized the recent application of ATRP in biosensing. Particularly, future study and prospect were envisioned.
- Atom transfer radical polymerization,
- Signal amplification,
- Biosensing,
- Deoxyribonucleic acid,
- Protein,
- Review
1. [1]
  1 Matyjaszewski K, Xia J H. Chem. Rev., 2001, 101(9): 2921-2990
2. [2]
  2 Srivastava A, Mishra V, Singh P, Kumar R. J. Appl. Polym. Sci., 2012, 126(2): 395-407
3. [3]
  3 Bunha A K, Mangadlao J, Felipe M J, Pangilinan K, Advincula R. Macromol. Rapid. Comm., 2012, 33(14): 1214-1219
4. [4]
  4 Gilroy J B, Lunn D J, Patra S K, Winnik M A, Manners I. Macromolecules, 2012, 45(14): 5906-5815
5. [5]
  5 Yao Z L, Tam K C. Polymer, 2012, 53(16): 3446-3453
6. [6]
  6 Nguyen A T, Baggerman J, Paulusse J M J, Zuilhof H, van Rijn C J M. Langmuir, 2012, 28(1): 604-610
7. [7]
  7 Nguyen A T, Baggerman J, Paulusse J M J, van Rijn C J M, Zuilhof H. Langmuir, 2011, 27(6): 2587-2594
8. [8]
  8 Zhang Z B, Yuan S J, Zhu X L, Neoh K G, Kang E T. Biosens. Bioelectron., 2010, 25(5): 1102-1108
9. [9]
  9 Qian H, He L.Anal. Chem., 2009, 81(23): 9824-9827
10. [10]
  10 Wong A K Y, Krull U J. Anal. Chim. Acta, 2009, 639(1-2): 1-12
11. [11]
  11 Lou X H, Lewis M S, He L. Anal. Chem., 2005, 77(15): 4698-4705
12. [12]
  12 Lou X H, He L. Langmuir, 2006, 22(6): 2640-2646
13. [13]
  13 Wang J S, Matyjaszewski K. J. Am. Chem. Soc., 1995, 117(20): 5614-5615
14. [14]
  14 Matyjaszewski K. Curr. Org. Chem., 2002, 6(2): 67-82
15. [15]
  15 Matyjaszewski K, Ziegler M J, Arehart S V, Pakula T. J. Phys. Org. Chem., 2000, 13(12): 775-786
16. [16]
  16 Lutz J F, Neugebauer D, Matyjaszewski K. J. Am. Chem. Soc., 2003, 125(23): 6986-6993
17. [17]
  17 Lutz J F, Kirci B, Matyjaszewski K. Macromolecules, 2003, 36(9): 3136-3145
18. [18]
  18 Hong S C, Lutz J F, Inoue Y, Strissel C, Nuyken O, Matyjaszewski K. Macromolecules, 2003, 36(4): 1075-1082
19. [19]
  19 Hadjichristidis N, Pitsikalis M, Pispas S, Iatrou H. Chem. Rev., 2001, 101(12): 3747-3792
20. [20]
  20 Hong S C, Neugebauer D, Inoue Y, Lutz J F, Matyjaszewski K. Macromolecules, 2003, 36(1): 27-35
21. [21]
  21 Pitsikalis M, Pispas S, Mays J W, Hadjichristidis N. Blockcopolymers Polyelectrolytes Biodegradation, 1998, 135: 1-137
22. [22]
  22 Borner H G, Duran D, Matyjaszewski K, da Silva M, Sheiko S S. Macromolecules, 2002, 35(9): 3387-3394
23. [23]
  23 Gaynor S G, Edelman S, Matyjaszewski K. Macromolecules, 1996, 29(3): 1079-1081
24. [24]
  24 Matyjaszewski K, Gaynor S G, Kulfan A, Muller A H E. Macromolecules, 1997, 30(17): 5192-5194
25. [25]
  25 Matyjaszewski K, Gaynor S G, Muller A H E. Macromolecules, 1997, 30(23): 7034-7041
26. [26]
  26 Matyjaszewski K, Gaynor S G. Macromolecules, 1997, 30(23): 7042-7049
27. [27]
  27 Matyjaszewski K, Pyun J, Gaynor S G. Macromol. Rapid. Comm., 1998, 19(12): 665-670
28. [28]
  28 Matyjaszewski K. Polym. Int., 2003, 52(10): 1559-1565
29. [29]
  29 Beers K L, Gaynor S G, Matyjaszewski K, Sheiko S S, Moller M. Macromolecules, 1998, 31(26): 9413-9415
30. [30]
  30 Luzinov I, Minko S, Tsukruk V V. Prog. Polym. Sci., 2004, 29(7): 635-698
31. [31]
  31 Pyun J, Kowalewski T, Matyjaszewski K. Macromol. Rapid. Comm., 2003, 24(18): 1043-1059
32. [32]
  32 Liu Y, Cheng Q. Anal. Chem., 2012, 84(7): 3179-3186
33. [33]
  33 Liu Y, Dong Y, Jauw J, Linman M J, Cheng Q. Anal. Chem., 2010, 82(9): 3679-3685
34. [34]
  34 Qian H, He, L. Sensors and Actuators B, 2010, 150(2): 594-600
35. [35]
  35 He P, Zheng W M,Tucker E Z, Gorman C B, He L. Anal. Chem., 2008, 80(10): 3633-3639
36. [36]
  36 Wang J S, Matyjaszewski K. J. Am. Chem. Soc., 1995, 117(20): 5614-5615
37. [37]
  37 Chen J K, Li J Y. Sensors and Actuators B, 2010, 150(1): 314-320
38. [38]
  38 Lou X H, He L. Langmuir, 2006, 22(6): 2640-2646
39. [39]
  39 Zheng W M, He L. Anal. Bioanal. Chem., 2010, 397(6): 2261-2270
40. [40]
  40 Wu Y F, Liu S Q, He L. Anal. Chem., 2009, 81(16): 7015-7021
41. [41]
  41 Wu Y F, Liu S Q, He L. Analyst, 2011, 136(12): 2558-2563
42. [42]
  42 Wu Y F, Liu S Q, He L. Biosens. Bioelectron., 2010, 26(3): 970-975
43. [43]
  43 Wu Y F, Shi H Y, Yuan L A, Liu S Q. Chem. Commun., 2010, 46(41): 7763-7765
44. [44]
  44 Yuan LA, Wu Y F, Shi H Y, Liu S Q. Chem. Eur. J., 2011, 17(3): 976-983
45. [45]
  45 Shi H Y,Yuan L A, Wu Y F, Liu S Q. Biosens. Bioelectron., 2011, 26(9): 3788-3793
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