Citation: LI Ying, WU Ya-Feng, YUAN Liang, LIU Song-Qin. Application of Atom Transfer Radical Polymerization in Biosensing[J]. Chinese Journal of Analytical Chemistry, ;2012, 40(12): 1797-1802. doi: 10.3724/SP.J.1096.2012.20531 shu

Application of Atom Transfer Radical Polymerization in Biosensing

1.
School of Chemistry and Chemical Engineering, Southeast University, Nanjing 210096, China

Corresponding author: LIU Song-Qin,
Received Date: 23 May 2012
Available Online: 26 September 2012
Fund Project: 本文系国家自然科学基金资助项目(No.20875013) (No.20875013)

Atom transfer radical polymerization (ATRP) is a new class of signal amplification method. The polymer growth results in local accumulation of monomers to form long-chain polymers. The growth of long chain polymeric materials provides excess active groups for electroactive or photoactive molecules coupling, which in turn significantly increases the loading of signal molecules and enhanced detection sensitivity. This review introduced the mechanism of ATRP, summarized the recent application of ATRP in biosensing. Particularly, future study and prospect were envisioned.
- Atom transfer radical polymerization,
- Signal amplification,
- Biosensing,
- Deoxyribonucleic acid,
- Protein,
- Review
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