Citation: WANG Yan-Song, HE Ming-Rui, ZHANG Chun-Ye, FAN Shi-Hua, MA Ji, LI Hua-Feng. Determination of Multiresidual Fungicides in Environmental Water Samples by High Performance Liquid Chromatography Tandem Mass Spectrometry[J]. Chinese Journal of Analytical Chemistry, ;2012, 40(11): 1764-1771. doi: 10.3724/SP.J.1096.2012.20100 shu

Determination of Multiresidual Fungicides in Environmental Water Samples by High Performance Liquid Chromatography Tandem Mass Spectrometry

1.
¹ College of Sciences, Northeastern University, Shenyang 110004, China;

Corresponding author: WANG Yan-Song,
Received Date: 9 February 2012
Available Online: 3 May 2012

A sensitive multiresidual analytical method for simultaneous analysis of multiresidual fungicides in environmental water samples was developed. The method was based on solid phase extraction (SPE) followed by high performance liquid chromatography tandem mass spectrometry (LC-MS/MS). Qualitative and quantitative detection for the analytes was carried out under the multiple reaction monitoring (MRM) in positive ionization mode after chromatography separation. In this method we have studied the conversion rule, identified the chromatogram retention time of Z-isomer and E-isomer of flumorph and dimethomorph, confirmed their chromatographic behavior by monitoring concentrations of two isomers of them at room temperature under sunlight and optimized parameters that may affect the SPE procedure efficiency: the column type, the wash solvent and the elution solvent. The recoveries of the SPE gave levels ranged from 70.18% to 108.87%, all recoveries were acceptable, with relative standard deviation (RSD) ≤16.7%. The limit of quantification (LOQ, S/N=10) varied between 0.003 and 0.03 μg/L (except for fenhexamid 0.3 μg/L). The developed method was applied for the determination of multiresidual fungicides in 100 tap water samples and 6 environmental samples collected from Liaoning province in China. Total fungicides were not found in tap water samples. Azoxystrobin (0.051 μg/L), metalaxyl (0.217 μg/L) and dimethomorph (Z, E) (0.015 μg/L) were found in Pu river sample, dimethomorph (Z, E) (0.004 μg/L) was found in Hun river sample, the highest concentration level of metalaxyl was 0.217 μg/L in Pu river, the rest of fungicides remained undetected in river samples.
- Liquid chromatography-tandem mass spectrometry,
- Multiresidual fungicides,
- Solid phase extratione,
- Modifier,
- Environmental water
1. [1]
  1 Cheng J, Xia Y T, Zhou Y W, Guo F, Chen G. Anal. Chim. Acta, 2011, 701 (1-2): 86-91
2. [2]
  2 Moral A, Sicilia M D, Rubio S. J. Chromatogr. A, 2009, 1216(18): 3740-3745
3. [3]
  3 Wang C, Wu Q H, Wu C X, Wang Z. J. Hazard. Mater., 2011, 185(1): 71-76
4. [4]
  4 Liu C, Qiang Z M, Tian F, Zhang T. Chemosphere, 2009, 76(5): 609-615
5. [5]
  5 Wu Q H, Li Y P, Wang C, Liu Z M, Zang X H, Zhou X, Wang Z. Anal. Chim. Acta, 2009, 638(2): 139-145
6. [6]
  6 Tang T, Qian K, Shi T Y, Wang F, Li J Q, Cao Y S. Anal. Chim. Acta, 2010, 680(1-2): 26-31
7. [7]
  7 Hayama T, Yada K, Onimaru S, Yoshida H, Todoroki K, Nohta H, Yamaguchi M. J. Chromatogr. A, 2007, 1141(2): 251-258
8. [8]
  8 Marín J M, Gracia-Lor E, Sancho J V, López F J, Hernández F. J. Chromatogr. A, 2009, 1216(9): 1410-1420
9. [9]
  9 Pan H J, Ho W H. Anal. Chim. Acta, 2004, 527 (1): 61-67
10. [10]
  10 Zhou Q X, Xiao J P, Ding Y J. Anal. Chim. Acta, 2007, 602(2): 223-228
11. [11]
  11 Giraudi G, Rosso I, Baggiani C, Giovannoli C, Vanni A, Grassi G. Anal. Chim. Acta, 1999, 392(1): 85-94
12. [12]
  12 Baggiani C, Baravalle P, Giraudi G, Tozzi C. J. Chromatogr. A, 2007, 1141 (2): 158-164
13. [13]
  13 Liu D H, Wang P, Zhou W F, Gu X, Chen Z S, Zhou Z Q. Anal. Chim. Acta, 2006, 555(2): 210-216
14. [14]
  14 WU Jie-Shan, FENG Jia-Wang, Ren Yong-Xia, LIU Lu, LIANG Ning. J. Agrochemicals., 2011, 50(10): 754-766
15. [15]
  吴洁珊, 冯家望, 任永霞, 刘陆, 梁宁. 农药, 2011, 50(10): 754-766
16. [16]
  15 Banerjee K, Oulkar D P, Dasgupta S, Patil S B, Patil S H, Savant R, Adsule P G. J. Chromatogr. A, 2007, 1173(1-2): 98-109
17. [17]
  16 Dujakovi-N, Gruji-S, Radiši-M, Vasiljevi-T, Lauševi-M. Anal. Chim. Acta, 2010, 678(1): 63-72
18. [18]
  17 Baugros J B, Giroud B, Dessalces G, Grenier-Loustalot M F, Cren-Oliv C. Anal. Chim. Acta, 2008, 607(2): 191-203
19. [19]
  18 WANG Yan-Song, YANG Chun-Hui, ZHANG Chun-Ye, ZHANG Feng-Qing, HE Ming-Rui, CUI Xiang-Yong, MA Ji. Chinese J. Anal Chem., 2012, 40 (2): 286-291
20. [20]
  王岩松, 杨春晖, 张春野, 张凤清, 贺明睿, 崔相勇, 马吉. 分析化学, 2012, 40(2): 286-291
21. [21]
  19 Ballesteros-Gómez A, Rubio S, Leeuwen S. J. Chromatogr. A, 2010, 1217(17): 5913-5921
22. [22]
  20 Dek E, Gyepes A, Stefanovits-Bányai É, Dernovics M. Food Res. Int., 2010, 43(10): 2452-2455
23. [23]
  21 Wang Y S, Fan S H, Cui X Y, He M R, Zhang F Q, Yang C H, Zhang C Y, Ma J. Talanta, 2011, 86(30): 221-226
24. [24]
  22 Ferrer C, Martínez-Bueno M J, Lozano A, Fernández-Alba A R. Talanta, 2011, 83(5): 1552-1561
1. [1]
  Yanhui Zhong , Ran Wang , Zian Lin . Analysis of Halogenated Quinone Compounds in Environmental Water by Dispersive Solid-Phase Extraction with Liquid Chromatography-Triple Quadrupole Mass Spectrometry. University Chemistry, 2024, 39(11): 296-303. doi: 10.12461/PKU.DXHX202402017
2. [2]
  Zunxiang Zeng , Yuling Hu , Yufei Hu , Hua Xiao . Analysis of Plant Essential Oils by Supercritical CO₂Extraction with Gas Chromatography-Mass Spectrometry: An Instrumental Analysis Comprehensive Experiment Teaching Reform. University Chemistry, 2024, 39(3): 274-282. doi: 10.3866/PKU.DXHX202309069
3. [3]
  Yuanyuan JIANG , Fangfang TU , Yuhong ZHANG , Shi CHEN , Jiayuan XIANG , Xinhui XIA . Preparation and electrochemical properties of high-stability cathode prelithiation additive. Chinese Journal of Inorganic Chemistry, 2025, 41(6): 1101-1111. doi: 10.11862/CJIC.20240441
4. [4]
  Jingzhao Cheng , Shiyu Gao , Bei Cheng , Kai Yang , Wang Wang , Shaowen Cao . 4-氨基-1H-咪唑-5-甲腈修饰供体-受体型氮化碳光催化剂的构建及其高效光催化产氢研究. Acta Physico-Chimica Sinica, 2024, 40(11): 2406026-. doi: 10.3866/PKU.WHXB202406026
5. [5]
  Xue Dong , Xiaofu Sun , Shuaiqiang Jia , Shitao Han , Dawei Zhou , Ting Yao , Min Wang , Minghui Fang , Haihong Wu , Buxing Han . 碳修饰的铜催化剂实现安培级电流电化学还原CO₂制C₂₊产物. Acta Physico-Chimica Sinica, 2025, 41(3): 2404012-. doi: 10.3866/PKU.WHXB202404012
6. [6]
  Runjie Li , Hang Liu , Xisheng Wang , Wanqun Zhang , Wanqun Hu , Kaiping Yang , Qiang Zhou , Si Liu , Pingping Zhu , Wei Shao . 氨基酸的衍生及手性气相色谱分离创新实验. University Chemistry, 2025, 40(6): 286-295. doi: 10.12461/PKU.DXHX202407059
7. [7]
  Zongyuan Chen , ChunSheng Shi , Yiwen Li , Ganlin Zu , Qiang Jin , Haishan Wang , Fujun Wang , Dekun Yan , Zhijun Guo , Wangsuo Wu . Measurement of Uranium Isotopes in Environmental Water Samples by Alpha-Spectroscopy: Design of an Undergraduate Radiochemistry Experiment. University Chemistry, 2025, 40(4): 353-358. doi: 10.12461/PKU.DXHX202406103
8. [8]
  Gaoyan Chen , Chaoyue Wang , Juanjuan Gao , Junke Wang , Yingxiao Zong , Kin Shing Chan . Heart to Heart: Exploring Cardiac CT. University Chemistry, 2024, 39(9): 146-150. doi: 10.12461/PKU.DXHX202402011
9. [9]
  Mingyang Men , Jinghua Wu , Gaozhan Liu , Jing Zhang , Nini Zhang , Xiayin Yao . 液相法制备硫化物固体电解质及其在全固态锂电池中的应用. Acta Physico-Chimica Sinica, 2025, 41(1): 2309019-. doi: 10.3866/PKU.WHXB202309019
10. [10]
  Haodong JIN , Qingqing LIU , Chaoyang SHI , Danyang WEI , Jie YU , Xuhui XU , Mingli XU . NiCu/ZnO heterostructure photothermal electrocatalyst for efficient hydrogen evolution reaction. Chinese Journal of Inorganic Chemistry, 2025, 41(6): 1068-1082. doi: 10.11862/CJIC.20250048
11. [11]
  Chongjing Liu , Yujian Xia , Pengjun Zhang , Shiqiang Wei , Dengfeng Cao , Beibei Sheng , Yongheng Chu , Shuangming Chen , Li Song , Xiaosong Liu . Understanding Solid-Gas and Solid-Liquid Interfaces through Near Ambient Pressure X-Ray Photoelectron Spectroscopy. Acta Physico-Chimica Sinica, 2025, 41(2): 100013-. doi: 10.3866/PKU.WHXB202309036
12. [12]
  Jiahe LIU , Gan TANG , Kai CHEN , Mingda ZHANG . Effect of low-temperature electrolyte additives on low-temperature performance of lithium cobaltate batteries. Chinese Journal of Inorganic Chemistry, 2025, 41(4): 719-728. doi: 10.11862/CJIC.20250023
13. [13]
  Xiaowu Zhang , Pai Liu , Qishen Huang , Shufeng Pang , Zhiming Gao , Yunhong Zhang . Acid-Base Dissociation Equilibrium in Multiphase System: Effect of Gas. University Chemistry, 2024, 39(4): 387-394. doi: 10.3866/PKU.DXHX202310021
14. [14]
  Asif Hassan Raza , Shumail Farhan , Zhixian Yu , Yan Wu . 用于高效制氢的双S型ZnS/ZnO/CdS异质结构光催化剂. Acta Physico-Chimica Sinica, 2024, 40(11): 2406020-. doi: 10.3866/PKU.WHXB202406020
15. [15]
  Qingqing SHEN , Xiangbowen DU , Kaicheng QIAN , Zhikang JIN , Zheng FANG , Tong WEI , Renhong LI . Self-supporting Cu/α-FeOOH/foam nickel composite catalyst for efficient hydrogen production by coupling methanol oxidation and water electrolysis. Chinese Journal of Inorganic Chemistry, 2024, 40(10): 1953-1964. doi: 10.11862/CJIC.20240028
16. [16]
  Shuang Yang , Qun Wang , Caiqin Miao , Ziqi Geng , Xinran Li , Yang Li , Xiaohong Wu . Ideological and Political Education Design for Research-Oriented Experimental Course of Highly Efficient Hydrogen Production from Water Electrolysis in Aerospace Perspective. University Chemistry, 2024, 39(11): 269-277. doi: 10.12461/PKU.DXHX202403044
17. [17]
  Chunai Dai , Yongsheng Han , Luting Yan , Zhen Li , Yingze Cao . Ideological and Political Design of Solid-liquid Contact Angle Measurement Experiment. University Chemistry, 2024, 39(2): 28-33. doi: 10.3866/PKU.DXHX202306065
18. [18]
  Aoyu Huang , Jun Xu , Yu Huang , Gui Chu , Mao Wang , Lili Wang , Yongqi Sun , Zhen Jiang , Xiaobo Zhu . Tailoring Electrode-Electrolyte Interfaces via a Simple Slurry Additive for Stable High-Voltage Lithium-Ion Batteries. Acta Physico-Chimica Sinica, 2025, 41(4): 100037-. doi: 10.3866/PKU.WHXB202408007
19. [19]
  Jiao CHEN , Yi LI , Yi XIE , Dandan DIAO , Qiang XIAO . Vapor-phase transport of MFI nanosheets for the fabrication of ultrathin b-axis oriented zeolite membranes. Chinese Journal of Inorganic Chemistry, 2024, 40(3): 507-514. doi: 10.11862/CJIC.20230403
20. [20]
  Zhiwen HU , Weixia DONG , Qifu BAO , Ping LI . Low-temperature synthesis of tetragonal BaTiO₃ for piezocatalysis. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 857-866. doi: 10.11862/CJIC.20230462

Get Citation

PDF

XML

Metrics

PDF Downloads(0)
Abstract views(426)
HTML views(31)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142