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Citation: MENG Pinjia. Comparison of Analysis Characteristics of Hair Samples from Heroin and Methampetamine-Abusers[J]. Chinese Journal of Applied Chemistry, ;2014, 31(1): 103-108. doi: 10.3724/SP.J.1095.2014.30082 shu

Comparison of Analysis Characteristics of Hair Samples from Heroin and Methampetamine-Abusers

MENG Pinjia ^,

1.
College of Forensic Science, Chinese People's Public Security University, Beijing 100038, China

Corresponding author: MENG Pinjia,
Received Date: 4 February 2013
Available Online: 18 March 2013

The paper compared the characteristics of the hair samples from heroin and methamphetamineabusers based on the distribution characteristics of the two categories of drugs and their metabolists in hair.Analytes from heroin abuser's hair were collected in methanol by ultrasonication followed by liquid extraction at desirable pH.The methanol was evaporated to dryness and the residue was derivatized and detected by GC/MS.Hair from methamphetamine users was digested under alkali condition followed directly by small volume extraction in the solution.The analytes was derivatized in the extracted solution and detected by GC/MS.Two methods were validated by spiking standards in blank hair.The results show that the detection limits are 3 μg/g hair for 3 opioids(morphine,codeine and 6-monoacetyl morphine) with RSD of 2.5%~9.6%(n=5) and 0.05 μg/g hair for 4 amphetamines(amphetamine,methamphetamine,3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethamphetamine) with RSD of 5%~14%(n=5),respectively.
- drug abuse,
- hair analysis,
- heroin,
- methamphetamine
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