Citation:
ZHANG Yunhuai, DONG Xizhe, XIAO Peng, HE Huichao, LI Xiaoling. Detection of Insulin by Nickel Nanoparticles Modified Titanium Oxide Nanotube Electrode[J]. Chinese Journal of Applied Chemistry,
;2012, 29(8): 948-953.
doi:
10.3724/SP.J.1095.2012.00372
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Highly ordered TiO2 nanotube arrays(TiO2NTs) fabricated by anodization were employed as a substrate and loaded with Ni nanoparticles by pulse electrodeposition.The morphology and composites of titanium dioxide nanotubes and Ni/TiO2NTs electrodes were investigated using scanning electron microscopy and energy-dispersive X-ray spectroscopy,respectively.The Ni/TiO2NTs was used as an amperometric detector for electrocatalytic oxidation and determination of insulin.The results show that Ni/TiO2NTs electrode enables the oxidative detection of insulin at this modified electrode.The linear dynamic range of the detection is 0.8~1.6 μmol/L in 0.1 mol/L NaOH electrolyte,with a good sensitivity(0.49×10-3 A/(μmol·L-1·cm-2) and low detection limit(0.28 μmol/L).
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