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Citation: GAO Min, YANG Tianlin, MA Zhiqiang, ZHANG Jingjing. Synthesis and Antibacterial Activity of Its Metal Complexes of Salicyhydrazide and 3,5-Diiodosalicylalidehyde Schiff Base[J]. Chinese Journal of Applied Chemistry, ;2011, 28(10): 1167-1172. doi: 10.3724/SP.J.1095.2011.00618 shu

Synthesis and Antibacterial Activity of Its Metal Complexes of Salicyhydrazide and 3,5-Diiodosalicylalidehyde Schiff Base

1.
Key Laboratory of Energy Sources and Chemical Engineering, College of Chemistry and Chemical Engineering, Ningxia University, Yinchuan 750021

Corresponding author: YANG Tianlin,
Received Date: 18 October 2010
Available Online: 28 January 2011
Fund Project: 教育部科学技术研究重点基金(208195) (208195)

Four coordination compounds of transition metal with 3,5-diiodo-salicylalidehyde and salicyhydrazide Schiff base have been synthesized in pyridine and DMF solvents.These ligand and complexes were characterized by UV and IR spectra,TG-DTG,elemental analysis,and molar conductance analysis.The interactions of the complexes with DNA were investigated by UV and fluorescence spectroscopies,which show that the binding mode of the complexes with ct-DNA was intercalation.In addition,the biological activity test reveals that the complexes have potentially catalytic and antibacterial activity towards superoxide anion radical O₂^-· and Micrococcus luteus.
- iodine-containing Schiff base,
- transition metal complexes,
- spectrum character,
- antibacterial activity
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