Synthesis and Antitumor Activity of Rhodanine Methylene-Substituted Levofloxacin Derivatives
- Corresponding author: Hong-Yan CUI, lee7758521_1@163.com Guo-Qiang HU, hgqxy@sina.com.cn
Citation: Hui-Li ZHANG, Hong-Yan CUI, Wen-Long HUANG, Guo-Qiang HU. Synthesis and Antitumor Activity of Rhodanine Methylene-Substituted Levofloxacin Derivatives[J]. Chinese Journal of Applied Chemistry, ;2021, 38(2): 188-194. doi: 10.19894/j.issn.1000-0518.200199
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Reagents and conditions: i) H2O, reflux; ii) N2H4·H2O, reflux; iii) K3[Fe(CN)6], NH4OH, CHCl3, rt; iv) rhodanines, HOAc, NaOAc, reflux