Citation: FANG Lan-Yun, JIANG Yan-Hua, LI Ji-Ge, QIU Qiao-Li, JIN Mi-Cong, ZHANG Dan-Dan, ZHANG Yu-Mei. Determination of Bongkrekic Acid in Food by Dispersive Solid Phase Extraction-High Performance Liquid Chromatography-Tandem Mass Spectrometry Using Nitro Modified Zirconium Metal Organic Framework[J]. Chinese Journal of Analytical Chemistry, ;2023, 51(6): 1024-1032. doi: 10.19756/j.issn.0253-3820.231040 shu

Determination of Bongkrekic Acid in Food by Dispersive Solid Phase Extraction-High Performance Liquid Chromatography-Tandem Mass Spectrometry Using Nitro Modified Zirconium Metal Organic Framework

1.
Key Laboratory of Health Risk Appraisal for Trace Toxic Chemicals of Zhejiang Province, Ningbo Municipal Center for Disease Control and Prevention, Ningbo 315010, China;
2.
Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China;
3.
School of Basic Medical Sciences, Ningxia Medical University, Yinchuan 750004, China

Corresponding author: ZHANG Yu-Mei, 23858956@qq.com
Received Date: 10 February 2023
Revised Date: 7 April 2023

Fund Project: Supported by the Basic Public Welfare Research Project of Zhejiang Province (No. LGC22H260002), the Ningbo Public Welfare Key Project (No. 2022S091) and the Ningxia Natural Science Foundation (No. 2022AAC03208).

Dispersive solid phase extraction (DSPE) using nitro modified zirconium-based metal organic framework (NO₂-MOF) as adsorbent for determination of bongkrekic acid in food was developed. The synthesized NO₂-MOF were characterized by scanning electron microscopy (SEM), thermogravimetric analysis (TGA), infrared spectroscopy (IR), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS) and nitrogen adsorption experiment, etc, indicating that a structural stable MOF material with large BET surface area was obtained. There existed electrostatic interaction, π-π stacking, hydrogen bond and other weak intermolecular interactions between MOF and bongkrekic acid molecules to achieve selective adsorption of target molecules. Main experimental factors affecting DSPE were optimized, including pH value, amount of the adsorbent, extraction time, and type of desorption solvent. The established method was applied to detection of bongkrekic acid in auricularia auricula and rice flour, with limit of quantification of 1.6 μg/kg, and limit of detection of 0.5 μg/kg. In conclusion, the established method for determination of bongkrekic acid in food by DSPE had the advantages such as short pretreatment time, high sensitivity and precision with satisfactory recoveries of 75%-96%, and was environmentally friendly. This work provided a more reliable technique for determination of extremely trace amount of bongkrekic acid in related food such as auricularia auricula, tremella and rice flour.
- Nitro modified,
- Zirconium metal organic framework,
- Dispersive solid phase extraction,
- High performance liquid chromatography-mass spectrometry,
- Bongkrekic acid,
- Food
1. [1]
  MOEBIUS N, ROSS C, SCHERLACH K, ROHM B, ROTH M, HERTWECK C. Chem. Biol., 2012, 19(9):1164-1174.
2. [2]
  MATSUMOTO K, SUYAMA M, FUJITA S, MORIWAKI T, SATO Y, ASO Y, MUROSHITA S, MATSUO H, MONDA K, OKUDA K, ABE M, FUKUNAGA H, KANO A, SHINDO M. Chem. Eur. J., 2015, 21(32):11590-11602.
3. [3]
4. [4]
5. [5]
6. [6]
7. [7]
8. [8]
9. [9]
10. [10]
  MAYA F, CABELLO C P, FRIZZARIN R M, ESTELA J M, PALOMINO G T, CERDA V. TrAC, Trends Anal. Chem., 2017, 90:142-152.
11. [11]
  LIAN L, ZHANG X, HAO J, LV J, WANG X, ZHU B, LOU D J. J. Chromatogr. A, 2018, 1579:1-8.
12. [12]
  RAHMAN M M, ABD EL-ATY A M, KIM S W, SHIN S C, SHIN H C, SHIM J H. J. Sep. Sci., 2017, 40(1):203-212.
13. [13]
  CASTILLO-GARCÍA M L, AGUILAR-CABALLOS M P, GOMEZ-HENS A. TrAC, Trends Anal. Chem., 2016, 82:385- 393.
14. [14]
  KHEZELI T, DANESHFAR A. TrAC, Trends Anal. Chem., 2017, 89:99-118.
15. [15]
  RÍOS A, ZOUGAGH M. TrAC, Trends Anal. Chem., 2016, 84:72-83.
16. [16]
  SOCAS-RODRÍGUEZ B, HERRERA-HERRERA A V, ASENSIO-RAMOS M, HERNÁNDEZ-BORGES J. J. Chromatogr. A, 2014, 1357:110-146.
17. [17]
  DE TOFFOLI A L, MACIEL E V S, FUMES B H, LANÇAS F M. J. Sep. Sci., 2018, 41(1):288-302.
18. [18]
  RUIZ F J, RIPOLL L, HIDALGO M, CANALS A. Talanta, 2019, 191:162-170.
19. [19]
  ZHANG H, XIONG P, LI G. TrAC, Trends Anal. Chem., 2020, 131:116015.
20. [20]
21. [21]
  DOU Y, GUO L, LI G, LV X, XIA L, YOU J. Microchem. J., 2019, 146:366-373.
22. [22]
  RADA Z H, ABID H R, SUN H, SHANG J, LI J, HE Y, LIU S, WANG S. Prog. Nat. Sci.:Mater. Int., 2018, 28(2):160- 167.
23. [23]
  HIRA S A, NAGAPPAN S, ANNAS D, KUMAR Y A, PARK K H. Electrochem. Commun., 2021, 125:107012.
24. [24]
  GARIBAY S J, COHEN S M. Chem. Commun., 2010, 46(41):7700-7702.
25. [25]
  LU D, LIU C, QIN M, DENG J, SHI G, ZHOU T. Anal. Chim. Acta, 2020, 1133:88-98.
1. [1]
  Yanhui Zhong , Ran Wang , Zian Lin . Analysis of Halogenated Quinone Compounds in Environmental Water by Dispersive Solid-Phase Extraction with Liquid Chromatography-Triple Quadrupole Mass Spectrometry. University Chemistry, 2024, 39(11): 296-303. doi: 10.12461/PKU.DXHX202402017
2. [2]
  Wenxiu Yang , Jinfeng Zhang , Quanlong Xu , Yun Yang , Lijie Zhang . Bimetallic AuCu Alloy Decorated Covalent Organic Frameworks for Efficient Photocatalytic Hydrogen Production. Acta Physico-Chimica Sinica, 2024, 40(10): 2312014-. doi: 10.3866/PKU.WHXB202312014
3. [3]
  Zunxiang Zeng , Yuling Hu , Yufei Hu , Hua Xiao . Analysis of Plant Essential Oils by Supercritical CO₂Extraction with Gas Chromatography-Mass Spectrometry: An Instrumental Analysis Comprehensive Experiment Teaching Reform. University Chemistry, 2024, 39(3): 274-282. doi: 10.3866/PKU.DXHX202309069
4. [4]
  Shengbiao Zheng , Liang Li , Nini Zhang , Ruimin Bao , Ruizhang Hu , Jing Tang . Metal-Organic Framework-Derived Materials Modified Electrode for Electrochemical Sensing of Tert-Butylhydroquinone: A Recommended Comprehensive Chemistry Experiment for Translating Research Results. University Chemistry, 2024, 39(7): 345-353. doi: 10.3866/PKU.DXHX202310096
5. [5]
  Lu XU , Chengyu ZHANG , Wenjuan JI , Haiying YANG , Yunlong FU . Zinc metal-organic framework with high-density free carboxyl oxygen functionalized pore walls for targeted electrochemical sensing of paracetamol. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 907-918. doi: 10.11862/CJIC.20230431
6. [6]
  Bin HE , Hao ZHANG , Lin XU , Yanghe LIU , Feifan LANG , Jiandong PANG . Recent progress in multicomponent zirconium?based metal-organic frameworks. Chinese Journal of Inorganic Chemistry, 2024, 40(11): 2041-2062. doi: 10.11862/CJIC.20240161
7. [7]
  Simin Fang , Hong Wu , Sizhe Sheng , Lingling Li , Yuxi Wang , Hongchun Li , Jun Jiang . The Food Kingdom Lecture Series: The Science behind Color. University Chemistry, 2024, 39(9): 177-182. doi: 10.12461/PKU.DXHX202402012
8. [8]
  Yikai Wang , Xiaolin Jiang , Haoming Song , Nan Wei , Yifan Wang , Xinjun Xu , Cuihong Li , Hao Lu , Yahui Liu , Zhishan Bo . 氰基修饰的苝二酰亚胺衍生物作为膜厚不敏感型阴极界面材料用于高效有机太阳能电池. Acta Physico-Chimica Sinica, 2025, 41(3): 2406007-. doi: 10.3866/PKU.WHXB202406007
9. [9]
  Mingyang Men , Jinghua Wu , Gaozhan Liu , Jing Zhang , Nini Zhang , Xiayin Yao . 液相法制备硫化物固体电解质及其在全固态锂电池中的应用. Acta Physico-Chimica Sinica, 2025, 41(1): 2309019-. doi: 10.3866/PKU.WHXB202309019
10. [10]
  Fan Wu , Wenchang Tian , Jin Liu , Qiuting Zhang , YanHui Zhong , Zian Lin . Core-Shell Structured Covalent Organic Framework-Coated Silica Microspheres as Mixed-Mode Stationary Phase for High Performance Liquid Chromatography. University Chemistry, 2024, 39(11): 319-326. doi: 10.12461/PKU.DXHX202403031
11. [11]
  Tiantian MA , Sumei LI , Chengyu ZHANG , Lu XU , Yiyan BAI , Yunlong FU , Wenjuan JI , Haiying YANG . Methyl-functionalized Cd-based metal-organic framework for highly sensitive electrochemical sensing of dopamine. Chinese Journal of Inorganic Chemistry, 2024, 40(4): 725-735. doi: 10.11862/CJIC.20230351
12. [12]
  Jing SU , Bingrong LI , Yiyan BAI , Wenjuan JI , Haiying YANG , Zhefeng Fan . Highly sensitive electrochemical dopamine sensor based on a highly stable In-based metal-organic framework with amino-enriched pores. Chinese Journal of Inorganic Chemistry, 2024, 40(7): 1337-1346. doi: 10.11862/CJIC.20230414
13. [13]
  Yanan Liu , Yufei He , Dianqing Li . Preparation of Highly Dispersed LDHs-based Catalysts and Testing of Nitro Compound Reduction Performance: A Comprehensive Chemical Experiment for Research Transformation. University Chemistry, 2024, 39(8): 306-313. doi: 10.3866/PKU.DXHX202401081
14. [14]
  Gaoyan Chen , Chaoyue Wang , Juanjuan Gao , Junke Wang , Yingxiao Zong , Kin Shing Chan . Heart to Heart: Exploring Cardiac CT. University Chemistry, 2024, 39(9): 146-150. doi: 10.12461/PKU.DXHX202402011
15. [15]
  Ke Li , Chuang Liu , Jingping Li , Guohong Wang , Kai Wang . 钛酸铋/氮化碳无机有机复合S型异质结纯水光催化产过氧化氢. Acta Physico-Chimica Sinica, 2024, 40(11): 2403009-. doi: 10.3866/PKU.WHXB202403009
16. [16]
  Yukun Chang , Haoqin Huang , Baolei Wang . Preparation of Trans-Cinnamic Acid via “One-Pot” Protocol of Aldol Condensation-Hydrolysis Reaction: Recommending an Improved Organic Synthesis Experiment. University Chemistry, 2024, 39(4): 322-328. doi: 10.3866/PKU.DXHX202309095
17. [17]
  Aiai WANG , Lu ZHAO , Yunfeng BAI , Feng FENG . Research progress of bimetallic organic framework in tumor diagnosis and treatment. Chinese Journal of Inorganic Chemistry, 2024, 40(10): 1825-1839. doi: 10.11862/CJIC.20240225
18. [18]
  Tianyun Chen , Ruilin Xiao , Xinsheng Gu , Yunyi Shao , Qiujun Lu . Synthesis, Crystal Structure, and Mechanoluminescence Properties of Lanthanide-Based Organometallic Complexes. University Chemistry, 2024, 39(5): 363-370. doi: 10.3866/PKU.DXHX202312017
19. [19]
  Ran HUO , Zhaohui ZHANG , Xi SU , Long CHEN . Research progress on multivariate two dimensional conjugated metal organic frameworks. Chinese Journal of Inorganic Chemistry, 2024, 40(11): 2063-2074. doi: 10.11862/CJIC.20240195
20. [20]
  Xiaowu Zhang , Pai Liu , Qishen Huang , Shufeng Pang , Zhiming Gao , Yunhong Zhang . Acid-Base Dissociation Equilibrium in Multiphase System: Effect of Gas. University Chemistry, 2024, 39(4): 387-394. doi: 10.3866/PKU.DXHX202310021

Get Citation

PDF

XML

Metrics

PDF Downloads(14)
Abstract views(1337)
HTML views(52)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142