Citation: DU Wan-Qing, SONG Wen-Qi, LIANG Tian-Yu, SUN Xiao-Fei, TANG Li-Jun, ZHONG Ke-Li. Synthesis and Application of Near Infrared Mercury (Ⅱ) Fluorescent Probe Based on Dicyanoisophorone[J]. Chinese Journal of Analytical Chemistry, ;2023, 51(3): 421-428. doi: 10.19756/j.issn.0253-3820.221583 shu

Synthesis and Application of Near Infrared Mercury (Ⅱ) Fluorescent Probe Based on Dicyanoisophorone

1.
College of Chemistry and Chemical Engineering, Bohai University, Jinzhou 121013, China;
2.
College of Food Science and Technology, Bohai University, Jinzhou 121013, China

Corresponding author: ZHONG Ke-Li, zhongkeli2000@bhu.edu.cn
Received Date: 25 November 2022
Revised Date: 18 January 2023

Fund Project: Supported by the National Natural Science Foundation of China (Nos. 22278038, 32201948), the Scientific Research Fund of Liaoning Provincial Education Department (Nos. LJKMZ20221480, LJKQZ2021135) and the Program for Distinguished Professor of Liaoning Province.

A novel fluorescence probe SAM-S with near infrared emission (675 nm) was synthesized by a two-step reaction using dicyanoisophorone and 4-diethylaminosalicylaldehyde as raw materials. The probe showed a weak fluorescence in CH₃OH/HEPES buffer (1∶1, V/V, pH = 7.4) solution, and the fluorescence was significantly enhanced only after adding Hg²⁺. Therefore, a new method for detecting Hg²⁺ was established. SAM-S for detection of Hg²⁺ possessed many advantages such as good selectivity, strong anti-interference ability, and low detection limit (0.49 μmol/L). The content of Hg²⁺ in lake water and tap water was determined by this method, and the recoveries were between 99.9% and 104.8%. In addition, the probe SAM-S could be produced into fluorescent ink, which was expected to be used for trademark packaging. Meanwhile, because of the low toxicity of SAM-S, probe SAM-S could perform fluorescence imaging of Hg²⁺ in living cells.
- Near infrared emission,
- Fluorescent probe,
- Mercury ion,
- Water sample,
- Bioimaging
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