Citation: ZHANG Si-Cai,  LIU Xing-Quan,  YANG Mei-Ting,  JI Shuang,  GUO Zhi-Jun,  DU Yan. Recent Advances in Point-of-Care Diagnosis for Foodborne Pathogens[J]. Chinese Journal of Analytical Chemistry, ;2021, 49(10): 1631-1639. doi: 10.19756/j.issn.0253-3820.211024 shu

Recent Advances in Point-of-Care Diagnosis for Foodborne Pathogens

  • Corresponding author: GUO Zhi-Jun,  DU Yan, 
  • Received Date: 11 January 2021
    Revised Date: 28 March 2021

    Fund Project: Supported by the National Natural Science Foundation of China (Nos.31960506, 21874129) and the International Scientific Cooperation Project of Jilin Scientific and Technological Development Program (No.20200801044GH).

  • Food safety is a global health issue. The food-borne pathogens, such as Escherichia coli, Salmonella, Staphylococcus aureus, etc., are the main causes of food-borne diseases and food poisoning. The contamination of different foods (Like fruits, vegetables, meat and seafood) by the food-borne pathogens has threatened the food safety so long. The rapid detection of food-borne pathogens is critical to public health and food safety. However, traditional detection methods are mostly cumbersome and time-consuming, and are difficult to meet the needs of quick diagnosis and quick examination. Point-of-care testing (POCT) technology, as an emerging on-site rapid detection and analysis technology, shows many advantages such as simple operation, fast, portable and automated. POCT technology, as a food-borne pathogen detection method that has developed rapidly in recent years, provides a new way for low-cost, high-sensitivity and high-specificity detection of food-borne pathogens. At present, the technologies used in POCT are mainly divided into optical technologies and biosensor technologies, which are mainly based on immunological and biochemical reactions. This review reports the current research status of the application of POCT technology based on colorimetry, paper-based, microfluidic, electromagnetic sensing, and commercially available portable reading platforms in the detection of food-borne pathogens in recent years.
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