Citation: XIAO Cong, LIAN Wen-Jing, YAO Hui-Qin, YANG Bao-Hua, LIU Hong-Yun. Progress of Molecularly Imprinted Polymers-Electrochemiluminescence Antibiotic Sensors Based on Signal Amplification Strategies[J]. Chinese Journal of Analytical Chemistry, ;2022, 50(2): 173-182. doi: 10.19756/j.issn.0253-3820.210789 shu

Progress of Molecularly Imprinted Polymers-Electrochemiluminescence Antibiotic Sensors Based on Signal Amplification Strategies

1.
Key Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China;
2.
College of Basic Science, Tianjin Agricultural University, Tianjin 300384, China;
3.
School of Basic Medicine, Ningxia Medical University, Yinchuan 750004, China;
4.
Yanjing Medical College, Capital Medical University, Beijing 101300, China

Corresponding author: LIU Hong-Yun, liuhongyun@bnu.edu.cn
Received Date: 12 October 2021
Revised Date: 20 November 2021

Fund Project: Supported by the Key R&D Program of Ningxia Hui Autonomous Region of China (No.2018BEG03017), the Beijing Natural Science Foundation (No.2182027) and the Scientific Research Project of Tianjin Education Commission (No.2020KJ099)

It is significant to develop efficient, rapid and simple methods for antibiotic detection because excess antibiotic residues have become one of the most serious threats to global public health. Molecularly imprinted polymers (MIPs), as artificial chemical receptors, can recognize and bind target molecules with high affinity and selectivity. Electrochemiluminescence (ECL) is a mature and widely used analytical technique. As a new analytical and detection technology, MIP-ECL technique is a very promising method for detection of antibiotic residues due to the advantages such as good selectivity, high sensitivity and low cost. In this review, the latest development of MIP-ECL antibiotic sensors, especially constructed with signal amplification strategies, is briefly introduced. Finally, current challenges and future perspectives for MIP-ECL sensors are discussed and prospected.
- Antibiotics,
- Molecularly imprinted polymer,
- Sensor,
- Electrochemiluminescence,
- Signal amplification,
- Review
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