Citation: XIAO Cong, LIAN Wen-Jing, YAO Hui-Qin, YANG Bao-Hua, LIU Hong-Yun. Progress of Molecularly Imprinted Polymers-Electrochemiluminescence Antibiotic Sensors Based on Signal Amplification Strategies[J]. Chinese Journal of Analytical Chemistry, ;2022, 50(2): 173-182. doi: 10.19756/j.issn.0253-3820.210789 shu

Progress of Molecularly Imprinted Polymers-Electrochemiluminescence Antibiotic Sensors Based on Signal Amplification Strategies

1.
Key Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China;
2.
College of Basic Science, Tianjin Agricultural University, Tianjin 300384, China;
3.
School of Basic Medicine, Ningxia Medical University, Yinchuan 750004, China;
4.
Yanjing Medical College, Capital Medical University, Beijing 101300, China

Corresponding author: LIU Hong-Yun, liuhongyun@bnu.edu.cn
Received Date: 12 October 2021
Revised Date: 20 November 2021

Fund Project: Supported by the Key R&D Program of Ningxia Hui Autonomous Region of China (No.2018BEG03017), the Beijing Natural Science Foundation (No.2182027) and the Scientific Research Project of Tianjin Education Commission (No.2020KJ099)

It is significant to develop efficient, rapid and simple methods for antibiotic detection because excess antibiotic residues have become one of the most serious threats to global public health. Molecularly imprinted polymers (MIPs), as artificial chemical receptors, can recognize and bind target molecules with high affinity and selectivity. Electrochemiluminescence (ECL) is a mature and widely used analytical technique. As a new analytical and detection technology, MIP-ECL technique is a very promising method for detection of antibiotic residues due to the advantages such as good selectivity, high sensitivity and low cost. In this review, the latest development of MIP-ECL antibiotic sensors, especially constructed with signal amplification strategies, is briefly introduced. Finally, current challenges and future perspectives for MIP-ECL sensors are discussed and prospected.
- Antibiotics,
- Molecularly imprinted polymer,
- Sensor,
- Electrochemiluminescence,
- Signal amplification,
- Review
1. [1]
  DONG Y C, LI F T, WANG Y. Front. Chem., 2020, 8: 551.
2. [2]
  SUN Y M, ZHAO J L, LIANG L J. Microchim. Acta, 2021, 188(1): 21.
3. [3]
  KULIKOVA T, GORBATCHUK V, STOIKOV I, ROGOV A, EVTUGYN G, HIANIK T. Sensors, 2020,20(17): 4738.
4. [4]
  BOURSI B, MAMTANI R, HAYNES K, YANG Y X. Eur. J. Cancer, 2015, 51(17): 2655-2664.
5. [5]
  WU Q, LIU X S, DUN X L, SHABBIR M A B, PENG D P, YUAN Z H, WANG Y L. Microchem. J., 2021, 161: 105796.
6. [6]
  SHI Q Q, HUANG J, SUN Y N, YIN M Q, HU M, HU X F, ZHANG Z J, ZHANG G P. Spectrochim. Acta, Part A, 2018, 197: 107-113.
7. [7]
  FENG Y, ZHANG W J, LIU Y W, XUE J M, ZHANG S Q, LI Z J. Molecules, 2018, 23(8): 1953.
8. [8]
  ZAREJOUSHEGHANI M, RAHIMI P, BORSDORF H, ZIMMERMANN S, JOSEPH Y. Sensors, 2021, 21(7): 2406.
9. [9]
  WU P, HOU X D, XU J J, CHEN H Y. Chem. Rev., 2014, 114(21): 11027-11059.
10. [10]
  CHENG S T, LIU H M, ZHANG H, CHU G L, GUO Y M, SUN X. Sens. Actuators, B, 2020, 304: 127367.
11. [11]
  LIU Z Y, QI W J, XU G B. Chem. Soc. Rev., 2015, 44(1): 3117-3142.
12. [12]
  BENACHIO I, LOBATO A, GONÇALVES L M. J. Mol. Recognit., 2021, 34(3): e2878.
13. [13]
  YANG B, FU C, LI J P, XU G B. TrAC-Trends Anal. Chem., 2018, 105: 52-67.
14. [14]
15. [15]
16. [16]
  DONG Y P, ZHOU Y, WANG J, ZHU J J. Anal. Chem., 2016, 88(10): 5469-5475.
17. [17]
  KHOSHFETRAT S M, BAGHERI H, MEHRGARDI M A. Biosens. Bioelectron., 2018, 100: 382-388.
18. [18]
  WANG L, JIANG H M, CHAI Y Q, YUAN R, ZHUO Y. Chem. Commun., 2020, 56(63): 9000-9003.
19. [19]
  AL-KUTUBI H, VOCI S, RASSAEI L, SOJIC N, MATHWIG K. Chem. Sci., 2018, 9(48): 8946-8950.
20. [20]
  LI L L, CHEN Y, ZHU J J. Anal. Chem., 2017, 89(1): 358-371.
21. [21]
  LI X, LI J P, YIN W M, ZHANG L M. J. Solid State Electrochem., 2014, 18(7): 1815-1822.
22. [22]
  TIAN L, WU K X, HU Y, WANG Y, ZHAO Y J, CHEN R Z, LU J. Microchim. Acta, 2020, 187(6): 358.
23. [23]
  YUAN X Y, TAN Y J, WEI X P, LI J P. Luminescence, 2017, 32(7): 1116-1122.
24. [24]
  CAI J T, CHEN T, XU Y H, WEI S, HUANG W G, LIU R, LIU J Q. Biosens. Bioelectron., 2019, 124-125: 15-24.
25. [25]
  CHENG R Q, DING Y L, WANG Y G, WANG H, ZHANG Y, WEI Q. RSC Adv., 2021, 11(18): 11011-11019.
26. [26]
  CAO N, ZHAO F Q, ZENG B Z. Sens. Actuators, B, 2020, 313: 128042.
27. [27]
  CAO N, ZENG P, ZHAO F Q, ZENG B Z. Electrochim. Acta, 2018, 291: 18-23.
28. [28]
  KHONSARI Y N, SUN S G. J. Mater. Chem. B, 2021, 9(2): 471-478.
29. [29]
  CHEN X Q, LIU Y, MA Q. J. Mater. Chem. C, 2018, 6(5): 942-959.
30. [30]
  ZHAO W R, KANG T F, XU Y H, ZHANG X, LIU H, MING A J, LU L P, CHENG S Y, WEI F. Sens. Actuators, B, 2020, 306: 127563.
31. [31]
  MO G C, QIN D M, JIANG X H, ZHENG X F, MO W M, DENG B Y. Sens. Actuators, B, 2020, 310: 127852.
32. [32]
  JIANG Q L, ZHANG D N, CAO Y T, GAN N. J. Electroanal. Chem., 2017, 789: 1-8.
33. [33]
34. [34]
  MO G C, HE X C, ZHOU C Q, YA D M, FENG J S, YU C H, DENG B Y. Biosens. Bioelectron., 2019, 126: 558-564.
35. [35]
  LI S H, LI J P, MA X H, LIU C H, PANG C H, LUO J H. Microchem. J., 2019, 148: 397-403.
36. [36]
  CHEN S F, CHEN X Q, ZHANG L J, GAO J J, MA Q. ACS Appl. Mater. Interfaces, 2017, 9(6): 5430-5436.
37. [37]
  RONG Y W, HASSAN M M, OUYANG Q, CHEN Q S. Compr. Rev. Food Sci. Food Saf., 2021, 20(4): 3531-3578.
38. [38]
  JIN X C, FANG G Z, PAN M F, YANG Y K, BAI X Y, WANG S. Biosens. Bioelectron., 2018, 102: 357-364.
39. [39]
  GU Y, WANG J P, SHI H P, PAN M F, LIU B, FANG G Z, WANG S. Biosens. Bioelectron., 2019, 128: 129-136.
40. [40]
  CHEN S H, LI A M, ZHANG L Z, GONG J M. Anal. Chim. Acta, 2015, 896: 68-77.
41. [41]
  LIU M, ZHANG B, ZHANG M, HU X L, CHEN W, FANG G Z, WANG S. Sens. Actuators, B, 2020, 311: 127901.
42. [42]
  BABAMIRI B, SALIMI A, HALLAJ R. Biosens. Bioelectron., 2018, 117: 332-339.
43. [43]
  WANG D W, JIANG S H, LIANG Y Y, WANG X B, ZHUANG X M, TIAN C Y, LUAN F, CHEN L X. Talanta, 2022, 236: 122835.
44. [44]
  BABAMIRI B, SALIMI A, HALLAJ R, HASANZADEH M. Biosens. Bioelectron., 2018, 107: 272-279.
45. [45]
  WU B W, WANG Z H, XUE Z H, ZHOU X B, DU J, LIU X H, LU X Q. Analyst, 2012, 137(16): 3644-3652.
46. [46]
  LI S H, MA X H, PANG C H, WANG M Y, YIN G H, XU Z, LI J P, LUO J H. Biosens. Bioelectron., 2021, 176: 112944.
47. [47]
  MA X, PANG C H, LI S H, LI J P, WANG M Y, XIONG Y H, SU L J, LUO J H, XU Z, LIN L Y. ACS Appl. Mater. Interfaces, 2021, 13(35): 41987-41996.
48. [48]
  YU Y C, LU C, ZHANG M N. Anal. Chem., 2015, 87(15): 8026-8032.
49. [49]
  LI S H, LIU C H, YIN G H, ZHANG Q, LUO J H, WU N C. Biosens. Bioelectron., 2017, 91: 687-691.
50. [50]
51. [51]
  LI S H, LI J P, LIN Q Y, WEI X P. Analyst, 2015, 14(13): 472-477.
52. [52]
  CHEN H, SIMOSKA O, LIM K, GRATTIERI M, YUAN M W, DONG F Y, LEE Y S, BEAVER K, WELIWATTE S, GAFFNEY E M, MINTEER S D. Chem. Rev., 2020, 120(23): 12903-12993.
53. [53]
  LI S H, TAO H L, LI J P. Electroanalysis, 2012, 24(7): 1664-1670.
54. [54]
  LI J P, JIANG F Y, LI Y P, CHEN Z Q. Biosens. Bioelectron., 2011, 26(5): 2097-2101.
55. [55]
  LI J P, LI Y P, ZHANG Y, WEI G. Anal. Chem., 2012, 84(4): 1888-1893.
56. [56]
  LI J P, JIANG F Y, WEI X P. Anal. Chem., 2010, 82(14): 6074-6078.
57. [57]
  LI J P, LI S H, WEI X P, TAO H L, PAN H C. Anal. Chem., 2012, 84(22): 9951-9955.
58. [58]
  LIAN W J, LIANG J Y, SHEN L, JIN Y, LIU H Y. Biosens. Bioelectron., 2018, 100: 26-332.
59. [59]
  KHATAEE A R, FATHINIA M, HASANZADEH A, IRANIFAM M, MORADKHANNEJHAD L. J.Lumin., 2014, 149: 272-279.
60. [60]
  LIAN W J, YU X, WANG L, LIU H Y. J. Phys. Chem. C, 2015, 119(34): 20003-20010.
61. [61]
  ZHANG S Y, DING Y B, WEI H. Molecules, 2014, 19(8): 11933-11987.
62. [62]
  YANG T G, FU J Y, ZHENG S J, YAO H Q, JIN Y, LU Y L, LIU H Y. Biosens. Bioelectron., 2018, 108: 62-68.
63. [63]
64. [64]
  MA X H, LI S H, PANG C H, XIONG Y H, LI J P. Microchim. Acta, 2018, 185(12): 546.
65. [65]
  MA Y M, JIN X Y, XING Y L, NI G, PENG J. Anal. Methods, 2019, 11(15): 2033-2040.
66. [66]
  XING K, FAN R Q, DU X, ZHENG X B, ZHOU X S, GAI S, WANG P, YANG Y L. Sens. Actuators, B, 2019, 288: 307-315.
67. [67]
  WEI B M, ZHU W Z, LI K, LIU Q, ZHANG J T, KOU H Z, XU C Z, HE L, WANG H B. LWT-Food Sci. Technol., 2022, 153: 112416.
1. [1]
  Pengcheng Yan , Peng Wang , Jing Huang , Zhao Mo , Li Xu , Yun Chen , Yu Zhang , Zhichong Qi , Hui Xu , Henan Li . Engineering Multiple Optimization Strategy on Bismuth Oxyhalide Photoactive Materials for Efficient Photoelectrochemical Applications. Acta Physico-Chimica Sinica, 2025, 41(2): 100014-. doi: 10.3866/PKU.WHXB202309047
2. [2]
  Jiarong Feng , Yejie Duan , Chu Chu , Dezhen Xie , Qiu'e Cao , Peng Liu . Preparation and Application of a Streptomycin Molecularly Imprinted Electrochemical Sensor: A Suggested Comprehensive Analytical Chemical Experiment. University Chemistry, 2024, 39(8): 295-305. doi: 10.3866/PKU.DXHX202401016
3. [3]
  Peiling Li , Qing Feng , Hongling Yuan , Qin Wang . Live Interview Recording about the Penicillin Family. University Chemistry, 2024, 39(9): 122-127. doi: 10.3866/PKU.DXHX202311022
4. [4]
  Yongzhi LI , Han ZHANG , Gangding WANG , Yanwei SUI , Lei HOU , Yaoyu WANG . A two-dimensional metal-organic framework for the determination of nitrofurantoin and nitrofurazone in aqueous solution. Chinese Journal of Inorganic Chemistry, 2025, 41(2): 245-253. doi: 10.11862/CJIC.20240307
5. [5]
  Ziheng Zhuang , Xiao Xu , Kin Shing Chan . Superdrugs for Superbugs. University Chemistry, 2024, 39(9): 128-133. doi: 10.3866/PKU.DXHX202309040
6. [6]
  Meiqing Yang , Lu Wang , Haozi Lu , Yaocheng Yang , Song Liu . Recent Advances of Functional Nanomaterials for Screen-Printed Photoelectrochemical Biosensors. Acta Physico-Chimica Sinica, 2025, 41(2): 100018-. doi: 10.3866/PKU.WHXB202310046
7. [7]
  Junjie Zhang , Yue Wang , Qiuhan Wu , Ruquan Shen , Han Liu , Xinhua Duan . Preparation and Selective Separation of Lightweight Magnetic Molecularly Imprinted Polymers for Trace Tetracycline Detection in Milk. University Chemistry, 2024, 39(5): 251-257. doi: 10.3866/PKU.DXHX202311084
8. [8]
  Qiaoqiao BAI , Anqi ZHOU , Xiaowei LI , Tang LIU , Song LIU . Construction of pressure-temperature dual-functional flexible sensors and applications in biomedicine. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2259-2274. doi: 10.11862/CJIC.20240128
9. [9]
  Xingchao Zhao , Xiaoming Li , Ming Liu , Zijin Zhao , Kaixuan Yang , Pengtian Liu , Haolan Zhang , Jintai Li , Xiaoling Ma , Qi Yao , Yanming Sun , Fujun Zhang . 倍增型全聚合物光电探测器及其在光电容积描记传感器上的应用. Acta Physico-Chimica Sinica, 2025, 41(1): 2311021-. doi: 10.3866/PKU.WHXB202311021
10. [10]
  Shijie Li , Ke Rong , Xiaoqin Wang , Chuqi Shen , Fang Yang , Qinghong Zhang . Design of Carbon Quantum Dots/CdS/Ta₃N₅ S-Scheme Heterojunction Nanofibers for Efficient Photocatalytic Antibiotic Removal. Acta Physico-Chimica Sinica, 2024, 40(12): 2403005-. doi: 10.3866/PKU.WHXB202403005
11. [11]
  Wenda WANG , Jinku MA , Yuzhu WEI , Shuaishuai MA . Waste biomass-derived carbon modified porous graphite carbon nitride heterojunction for efficient photodegradation of oxytetracycline in seawater. Chinese Journal of Inorganic Chemistry, 2024, 40(4): 809-822. doi: 10.11862/CJIC.20230353
12. [12]
  Cen Zhou , Biqiong Hong , Yiting Chen . Application of Electrochemical Techniques in Supramolecular Chemistry. University Chemistry, 2025, 40(3): 308-317. doi: 10.12461/PKU.DXHX202406086
13. [13]
  Kexin Dong , Chuqi Shen , Ruyu Yan , Yanping Liu , Chunqiang Zhuang , Shijie Li . Integration of Plasmonic Effect and S-Scheme Heterojunction into Ag/Ag₃PO₄/C₃N₅ Photocatalyst for Boosted Photocatalytic Levofloxacin Degradation. Acta Physico-Chimica Sinica, 2024, 40(10): 2310013-. doi: 10.3866/PKU.WHXB202310013
14. [14]
  Jingwen Wang , Minghao Wu , Xing Zuo , Yaofeng Yuan , Yahao Wang , Xiaoshun Zhou , Jianfeng Yan . Advances in the Application of Electrochemical Regulation in Investigating the Electron Transport Properties of Single-Molecule Junctions. University Chemistry, 2025, 40(3): 291-301. doi: 10.12461/PKU.DXHX202406023
15. [15]
  Tiantian MA , Sumei LI , Chengyu ZHANG , Lu XU , Yiyan BAI , Yunlong FU , Wenjuan JI , Haiying YANG . Methyl-functionalized Cd-based metal-organic framework for highly sensitive electrochemical sensing of dopamine. Chinese Journal of Inorganic Chemistry, 2024, 40(4): 725-735. doi: 10.11862/CJIC.20230351
16. [16]
  Minna Ma , Yujin Ouyang , Yuan Wu , Mingwei Yuan , Lijuan Yang . Green Synthesis of Medical Chemiluminescence Reagents by Photocatalytic Oxidation. University Chemistry, 2024, 39(5): 134-143. doi: 10.3866/PKU.DXHX202310093
17. [17]
  Lu XU , Chengyu ZHANG , Wenjuan JI , Haiying YANG , Yunlong FU . Zinc metal-organic framework with high-density free carboxyl oxygen functionalized pore walls for targeted electrochemical sensing of paracetamol. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 907-918. doi: 10.11862/CJIC.20230431
18. [18]
  Jing SU , Bingrong LI , Yiyan BAI , Wenjuan JI , Haiying YANG , Zhefeng Fan . Highly sensitive electrochemical dopamine sensor based on a highly stable In-based metal-organic framework with amino-enriched pores. Chinese Journal of Inorganic Chemistry, 2024, 40(7): 1337-1346. doi: 10.11862/CJIC.20230414
19. [19]
  Borong Yu , Huijiao Zhang , Xinyu Zhang , Xiaoying Li , Shuming Chen , Zhangang Han . The Blue Elf in the Dark: Gradient Science Popularization Experiments on Chemiluminescence. University Chemistry, 2024, 39(9): 295-303. doi: 10.12461/PKU.DXHX202403107
20. [20]
  Linbao Zhang , Weisi Guo , Shuwen Wang , Ran Song , Ming Li . Electrochemical Oxidation of Sulfides to Sulfoxides. University Chemistry, 2024, 39(11): 204-209. doi: 10.3866/PKU.DXHX202401009

Get Citation

PDF

XML

Metrics

PDF Downloads(12)
Abstract views(648)
HTML views(100)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142