Citation: LI Si, GUO Xiao, HAO Chang-Long, XU Li-Guang, KUANG Hua, XU Chuan-Lai. DNA Driven Nanoprobe for Biological Sensing and Analysis[J]. Chinese Journal of Analytical Chemistry, ;2021, 49(7): 1198-1207. doi: 10.19756/j.issn.0253-3820.210405 shu

DNA Driven Nanoprobe for Biological Sensing and Analysis

State Key Lab of Food Science and Technology, School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China

Corresponding author: XU Chuan-Lai, xcl@jiangnan.edu.cn
Received Date: 1 April 2021
Revised Date: 4 June 2021

Fund Project: Supported by the National Natural Science Foundation of China (Nos. 21631005， 21673104)

DNA driven inorganic nanostructures not only display great flexibility in structure regulation and simplicity in surface modification but also exhibit specific optical properties, which shows numerous advantages in bio-sensing, bio-imaging, in situ analysis of living cells. Scientists developed a series of detection strategies for in situ analysis of important targets in living cells, which can be used for early diagnosis and treatment of serious diseases (such as cancers) and spurred the development of living systems. In this review, we introduce the biological applications of DNA driven inorganic nanostructures, which is anticipated to guide the development of living system, medical field and biological area further.
- DNA,
- Self-assembly,
- Nanostructure,
- Functional properties,
- Biological analysis,
- Review
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