Citation: LI Hui, YING Ying, CAO Zhen, LIU Guang-Yang, WANG Jing. Research Progress on Rapid Detection Technology Based on Smartphone and Lateral Flow Immunoassay[J]. Chinese Journal of Analytical Chemistry, ;2022, 50(1): 1-11. doi: 10.19756/j.issn.0253-3820.201488 shu

Research Progress on Rapid Detection Technology Based on Smartphone and Lateral Flow Immunoassay

LI Hui ¹ ,
YING Ying ¹ ,
CAO Zhen ^1,, ,
LIU Guang-Yang ² ,
WANG Jing ^1,,

1.
Key Laboratory of Agro-product Quality and Safety, Ministry of Agriculture and Rural Affairs, Institute of Quality Standard and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Beijing 100081, China;
2.
Key Laboratory of Vegetables Quality and Safety Control, Ministry of Agriculture and Rural Affairs, Ministry of Agriculture Vegetable Product Quality Safety Risk Assessment Laboratory, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China

Corresponding author: CAO Zhen, WANG Jing,
Received Date: 12 August 2021
Revised Date: 15 October 2021

Fund Project: Supported by the Agricultural Science and Technology Innovation Program of Chinese Academy of Agricultural Sciences (No.CAAS-ZDRW202011).

Lateral flow immunochromatographic strip is one of the mainstream rapid detection products in the current market. Smartphones with built-in high-definition cameras have been popular among consumers in recent years. By taking a picture via mobile phones, then analyzing with machine vision image recognition technology, the optical signal of strip developed color could be converted into digital signal based on visible light colorimetric analysis or fluorescence analysis technology. This has become a research hotspot of rapid detection to realize qualitative or quantitative determination based on strip color development in recent years. In this paper, the applications of rapid detection technology based on smartphone and lateral flow immunoassay in medical diagnosis, environmental monitoring and food safety were reviewed. Moreover, the quantitative detection mode, implementation method and challenges of rapid test strip products based on smartphone photography were also discussed and summarized, which could provide reference for its realization of multi-target analysis, on-site rapid qualitative and quantitative detection.
- Smartphone,
- Lateral flow immunoassay,
- Image recognition,
- Rapid detection,
- Colorimetric analysis,
- Fluorescence analysis,
- Review
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