Citation: ZHAO Li-Jun, ZHENG Wei, MAO Lan-Qun. Recent Advances of Ion-Selective Electrode for in Vivo Analysis in Brain Neurochemistry[J]. Chinese Journal of Analytical Chemistry, ;2019, 47(10): 1480-1491. doi: 10.19756/j.issn.0253-3820.191474 shu

Recent Advances of Ion-Selective Electrode for in Vivo Analysis in Brain Neurochemistry

1.
College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin 150001, China;
2.
Beijing National Laboratory for Molecular Science, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China;
3.
University of Chinese Academy of Sciences, Beijing 100049, China

Received Date: 3 August 2019
Revised Date: 26 August 2019

Fund Project: This work was supported by the National Natural Science Foundation of China (No. 21874139).

In the central nervous system, the realization of brain functions cannot be achieved without the participation of many ions, therefore, it is of great significance to real-time monitor the dynamic of ions in the living brain for understanding many physiological and pathological events. As a kind of electrochemical sensor, ion-selective electrode has been widely used for in vivo analysis and other fields in the past half century due to its low cost, simple operation and low energy consumption. This review mainly focuses on the development of ion-selective electrodes, and introduces its basic structure and application in the field of brain neurochemical analysis.
- Ion-selective electrode,
- In vivo analysis,
- Brain neurochemistry,
- Review
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