Citation: LIU Zhao-Miao, ZHAO Sheng, WANG Wen-Kai, LI Meng-Qi, PANG Yan, YIN Shen, XU Ying-Li. Influence of Geometric Configuration on Mixing Performance of Planar Chaotic Micro-mixer[J]. Chinese Journal of Analytical Chemistry, ;2019, 47(9): 1321-1329. doi: 10.19756/j.issn.0253-3820.191275
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As an important part of laboratory chip (LOC) and micro-total analysis system (μTAS), micro-mixer has been widely used in the fields of biological analysis and chemical synthesis, most of which are used in the pre-treatment part of the detection system to achieve sufficient mixing of detection samples and reagents and improve the detection accuracy and efficiency. In this work, a novel planar passive micro-mixer with narrow slits and obstacles arranged in a pentagonal mixing chamber was designed. The new micro-mixer made full use of the fluid jet characteristics and the vortex principle of the baffles to enhance the fluid disturbance and break the laminar state of fluid flow, which could effectively promote fluid mixing. The accuracy of numerical simulation was verified by the experimental method combining high-speed photography and Micro-PIV system, and the flow characteristics and mixing mechanism of the micro-mixer at different Reynolds Numbers (Re) were summarized. Under the premise of comprehensive consideration of the mixing index and pressure drop, the effects of the slit width, the gap width, the mixing chamber shape and the obstacle shape of the mixing performance and flow characteristics of the micro-mixer were analyzed. The results showed that the narrowing of the slit width could significantly improve the mixing index and achieve efficient mixing. When Re ≤ 5 and Re ≥ 20, the optimized pentagonal mixing chamber micro-mixer could increase the mixing index while reducing the pressure drop due to the introduction of the progressive expansion structure compared with the quadrilateral mixing chamber micro-mixer; When Re ≥ 20, the I-shaped baffle and the grooved baffle led to a higher mixing index than that the rectangular baffle. The results are helpful for the design and development of micro-mixers with efficient mixing function in microfluidic and micro-total analysis pre-processing parts.
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Keywords:
- Micro-mixer,
- Geometric configuration,
- Mixing index,
- Pressure drop
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