Citation: LIANG Si-Jia, MAO Ji-Kai, GONG Chen, YU Dong-Dong, ZHOU Jian-Guang. Research and Application Progress of Paper-based Microfluidic Sample Preconcentration[J]. Chinese Journal of Analytical Chemistry, ;2019, 47(12): 1878-1886. doi: 10.19756/j.issn.0253-3820.191251 shu

Research and Application Progress of Paper-based Microfluidic Sample Preconcentration

1.
Research Center for Analytical Instrumentation, Institute of Cyber-Systems and Control, State Key Laboratory of Industrial Control Technology, Zhejiang University, Hangzhou 310027, China;
2.
Department of Chemistry, Zhejiang University, Hangzhou 310027, China;
3.
Hospital of Zhejiang University, Zhejiang University, Hangzhou 310000, China

Received Date: 4 May 2019
Revised Date: 19 July 2019

Fund Project: This work was supported by the National Key Research and Development Program of China (No.2016YFC0800905) and the Key Research and Development Program of Zhejiang Province (No.2018C03G2011156).

Sample pretreatment is a key link in the whole process of analysis and detection. For samples whose original concentration is lower than the detection limit of analytical method, pre concentration technology is necessary, which is beneficial to improve the accuracy of the analytical method and expand the application range. However, conventional sample pre concentration technology is often cumbersome and depends on expensive equipment, resulting in the increased inspection time and cost. The paper-based microfluidic sample pre concentration technology is favored by domestic and foreign scholars for its easy preparation, low cost and high efficiency. This technology simplifies the operation process and reduces the detection cost. This paper focuses on the research and application progress of paper-based microfluidic sample preconcentration in recent years, including enrichment principle, paper-based material selection and device structure design, and the application of this technology. Finally, the development trend of this technology is prospected.
- Paper-based microfluidic,
- Sample preconcentration,
- Electrokinetic stacking,
- Review
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1.
沈阳化工大学材料科学与工程学院沈阳 110142