Citation: WEI Yu-Yao, SUN Zi-Qiao, REN Hao-Hui, LI Lei. Advances in Microdroplet Generation Methods[J]. Chinese Journal of Analytical Chemistry, ;2019, 47(6): 795-804. doi: 10.19756/j.issn.0253-3820.181745 shu

Advances in Microdroplet Generation Methods

WEI Yu-Yao ^1,2, ,
SUN Zi-Qiao ² ,
REN Hao-Hui ³ ,
LI Lei ^1,4

1.
CAS Key Laboratory of Cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, China;
2.
School of Environment and Energy Engineering, Beijing University of Civil Engineering and Architecture, Beijing 102616, China;
3.
Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, China;
4.
Beijing Key Laboratory of Cryo-Biomedical Engineering, Beijing 100190, China

Received Date: 29 November 2018

Fund Project: This work was supported by the National Natural Science Foundation of China (Nos.31770107, 21874116), the Natural Science Foundation of Beijing, China (No.3174047), the "Shi Pei Project"—High Level Students Training of Beijing Colleges and Universities and the Science and Technology Program from State Grid Corporation of China (No.5700-201955318A-0-0-00).

Microdroplets have been widely used in biology, chemistry, material science, and engineering, and the microdroplet generation methods are becoming more efficient and controllable. The development of the generation of microdroplets experienced traditional methods, microfluidic chip-based methods, and recently proposed off-chip methods. In this paper, we first briefly summarized the typical traditional methods and the microfluidic chip-based methods for microdroplet generation, and then emphatically introduced the principles, devices, and applications of the recently developed microdroplet generation methods. The advantages and disadvantages of these methods were discussed and the future development of microdroplet generation technology was also prospected.
- Microdroplet,
- Droplet microfluidics,
- Droplet generation,
- Review
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